Results 211 to 220 of about 661,223 (352)

MicroRNA-mediated regulation of glucose and lipid metabolism

Nature reviews. Molecular cell biology, 2021
Pamela Agbu, R. Carthew
semanticscholar   +1 more source

5′tRF‐GlyGCC Promotes Breast Cancer Progression via LDHA‐Mediated Glycolysis and Macrophage Polarization

Advanced Science, EarlyView.
5’tRF‐GlyGCC promotes breast cancer malignancy by binding to LDHA. This interaction, facilitated by FGFR1 and LDHA phosphorylation, enhances glycolysis. Additionally, 5’tRF‐GlyGCC/LDHA signaling recruits and polarizes macrophages into a pro‐tumor M2 state via CCL7, thus remodeling the tumor microenvironment.
Cheng Yi, Yunqing Lu, Xing Chang, Ying Wang, Jiawang Zhou, Guoyou Xie, Lijun Tao, Zhaotong Wang, Yifan Tian, Lihong Wang, Feng Tang, Yijing Zheng, Xinchen Yue, Jinping Lei, Xiansong Wang, Lichen Ge, Zhuojia Chen, Hongsheng Wang   +17 more
wiley   +1 more source

Salivary MicroRNAs as Innovative Biomarkers for Diagnosis and Prediction of the Oral Potentially Malignant Disorders Transition Towards Oral Cancer: A Systematic Review. [PDF]

J Clin Med
Osan C, Berindan-Neagoe I, Dinu C, Armencea G, Bran S, Kretschmer W, Baciut G, Onisor F, Baciut M.   +8 more
europepmc   +1 more source

<p>MicroRNA-34a suppresses aggressiveness of hepatocellular carcinoma by modulating <em>E2F1</em>, <em>E2F3</em>, and Caspase-3</p>

, 2019
Rui Han, Xinyi Chen, Ya Li, Shunjia Zhang, Ruibai Li, Lingeng Lu   +5 more
openalex   +2 more sources

Impulsivity and comorbid traits: a multi-step approach for finding putative responsible microRNAs in the amygdala [PDF]

, 2014
Andrzej Z. Pietrzykowski, Sabine Spijker
openalex   +1 more source

MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

, 2021
Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie   +8 more
openalex   +2 more sources

MicroRNA genes are transcribed by RNA polymerase II

EMBO Journal, 2004
Yoontae Lee, Minju Kim, Jinju Han, Kyu‐Hyun Yeom, Sanghyuk Lee, S. H. Baek, V. Kim   +6 more
semanticscholar   +1 more source

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

Advanced Science, EarlyView.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu, Leyi Wang, Tao Lv, Chen Jin, Qiong Wu, Yongjie Zhou, Gang Xu, Zhenyu Duan, Kui Luo, Jiayin Yang   +9 more
wiley   +1 more source

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer. [PDF]

Int J Mol Med
Li K, Yuan C.
europepmc   +1 more source

Targeting the Dynamics Between TAMs and CAR‐T Cells in Solid Tumor Therapies

Advanced Science, EarlyView.
This review highlights the critical role of tumor‐associated macrophages (TAMs) in affecting CAR‐T cell therapy effectiveness in solid tumors. TAMs contribute to immune suppression through cytokine secretion, immune checkpoint activation, and metabolic reprogramming, leading to CAR‐T cell exhaustion and reduced efficacy. The article explores strategies
Xiang Zhang, Hao Zheng, Zi‐Chang Liu, Ling‐Jie Luo, Xiao Dong, Xin‐Gang Cui, Yan‐Wei Wu, Liang Chen   +7 more
wiley   +1 more source