Results 131 to 140 of about 282,884 (301)
Circulating Non-Coding RNAs as Potential Diagnostic Biomarkers in Hepatocellular Carcinoma
Journal of Hepatocellular Carcinoma, 2022 Tingsong Chen The Second Department of Oncology, the Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of ChinaCorrespondence: Tingsong Chen, The Second Department of Oncology, the Seventh ...
Chen T
doaj
Exosomal microRNAs as potential biomarkers in pediatric Burkitt Lymphoma
, 2022 reservedBurkitt Lymphoma (BL) is a highly aggressive B-cell non Hodgkin lymphoma. It is the most frequent subtype of NHL in children and adolescents, accounting for 38% of patients from 0 to 14 years old. The current recommended approach of diagnosis and
RIZZATO, DOMENICO
core
Advanced Science, EarlyView.ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai +11 more
wiley +1 more source
The World Journal of Men's HealthPurpose: The poor retention and ambiguous differentiation of stem cells (SCs) within corpus cavernosum (CC) limit the cell application in erectile dysfunction (ED).
Daoyuan Hu +11 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Gastric cancer (GC) is a major global health concern, as its prevention and treatment remain significant challenges. The 8‐oxoguanine (o8G) modification of circRNAs, alongside their capacity to orchestrate liquid‐liquid phase separation (LLPS) and autophagy, plays a pivotal role in driving tumor progression and determining therapeutic outcomes.
Lei Peng +8 more
wiley +1 more source
MicroRNAs play a role in human embryonic stem cell differentiation into endothelial cells [PDF]
, 2011 PhDThe past recent years have seen a surge of evidence demonstrating the regulation of microRNAs (miRNAs) in a myriad of vascular biology events such as cardiogenesis.
Luo, Zhenling
core +1 more source
Advanced Science, EarlyView.This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen +14 more
wiley +1 more source
Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis
Advanced Science, EarlyView.A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa +5 more
wiley +1 more source
Cell‐Selective Delivery of RIBOTACs via an Anti‐EGFR Nanobody for Pancreatic Cancer Treatment
Advanced Science, EarlyView.This study introduces an innovative strategy for the tumor‐selective catalytic degradation of oncogenic non‐coding RNA by interfacing a ribonuclease‐recruiting small molecule (RIBOTAC) with an EGFR‐targeting nanobody via a CTSB (Cathepsin B)‐responsive linker.
Tianli Luo +15 more
wiley +1 more source
Sperm microRNAs related to fertility
, 2020 Spermatozoa is a cell type that carry much more than just male genomic DNA during the fertilization process. In recent years, epigenetic mechanisms related to sperm quality have been extensively studied.
Domingues, William Borges
core +2 more sources