Results 111 to 120 of about 97,236 (208)

The Application of Extracellular Vesicles Mediated miRNAs in Osteoarthritis: Current Knowledge and Perspective

open access: yesJournal of Inflammation Research, 2022
Xiaobin Shang,1,* Yan Fang,2,* Wenqiang Xin,3 Hongbo You1 1Department of Orthopaedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People’s Republic of China; 2Department of ...
Shang X, Fang Y, Xin W, You H
doaj  

Post-transcriptional modifications of platelet microRNAs.

open access: yes, 2012
(A) The relative frequency of nucleotide mutation ordered by position on the mature microRNA sequences. The majority of the nucleotide modifications were observed at the 3′ end of microRNAs, whereas the sequence of their seed region was relatively well ...
Hélène Plé (114528)   +5 more
core   +1 more source

The Cytoplasmic MicroRNA‐Production Complex Regulates MicroRNA Sorting to Extracellular Vesicles During Synaptogenesis

open access: yesAdvanced Science, EarlyView.
The mechanisms of microRNA cargo sorting to extracellular vesicles, important mediators of cell communication, are not fully understood. This study reveals that the microRNA‐production machinery acts as a ‘hub’ for the sorting of microRNAs to extracellular vesicles, a process regulated by dynamic organelle interactions.
Yuzhou Zeng   +6 more
wiley   +1 more source

MicroRNAs and developmental timing

open access: yes, 2015
MicroRNAs regulate temporal transitions in gene expression associated with cell fate progression and differentiation throughout animal development.
Ambros, Victor R.
core   +1 more source

Mechanically Regulated Secretion: How Physical Forces Instruct the Secretory Pathway and Remodel the Secretome

open access: yesAdvanced Science, EarlyView.
Mechanical cues, including ECM stiffness, stretch, compression, shear stress, and traction forces, remodel trafficking across the secretory pathway, from the ER and Golgi to endolysosomal compartments and the plasma membrane. The resulting secretome reshapes ECM composition and tissue mechanics, establishing feedback loops that support homeostasis or ...
Domenico Russo   +5 more
wiley   +1 more source

MicroRNAs found in all samples among the 50 most abundant microRNAs.

open access: yes, 2015
*Average on all samplesMicroRNAs found in all samples among the 50 most abundant microRNAs.
Suvi M. Kuosmanen (701393)   +5 more
core   +1 more source

Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation

open access: yesAdvanced Science, EarlyView.
Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir   +3 more
wiley   +1 more source

MicroRNAs play a role in human embryonic stem cell differentiation into endothelial cells [PDF]

open access: yes, 2011
PhDThe past recent years have seen a surge of evidence demonstrating the regulation of microRNAs (miRNAs) in a myriad of vascular biology events such as cardiogenesis.
Luo, Zhenling
core   +1 more source

MicroRNAs as Biomarkers of Brain Tumor [PDF]

open access: yes
Wojciech Jelski,1 Barbara Mroczko1,2 1Department of Biochemical Diagnostics, Medical University, Bialystok, Poland; 2Department of Neurodegeneration Diagnostics, Medical University, Bialystok, PolandCorrespondence: Wojciech Jelski, Department of ...
Jelski W, Mroczko B
core  

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

open access: yesAdvanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun   +12 more
wiley   +1 more source

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