Results 1 to 10 of about 264,030 (267)

Simple Mathematical Model Of Pathologic Microsatellite Expansions: When Self-Reparation Does Not Work [PDF]

J. Theor. Biol., 2006, v. 242, 401--408, 2007
We propose a simple model of pathologic microsatellite expansion, and describe an inherent self-repairing mechanism working against expansion. We prove that if the probabilities of elementary expansions and contractions are equal, microsatellite expansions are always self-repairing.
Amos, Angers, Barton, Bell, Boris Veytsman, Brinkmann, Brock, Brunner, Calabrese, Calabrese, Cleary, de Gennes, Di Rienzo, Ellegren, Ellegren, FitzSimmons, Garza, Goldstein, Gomes-Pereira, Harper, Harr, Huang, Kayser, Kruglyak, Kruglyak, Lai, Lai, Lai, Leila Akhmadeyeva, Libby, Makova, Mirkin, Monckton, Nielsen, Painter, Pearson, Pearson, Piñeiro, Primmer, Primmer, Schlötterer, Shinde, Shriver, Sibly, Sibly, Tachida, Whittaker, Xu, Yang   +48 more
arxiv   +3 more sources

Low-Sidelobe Pattern Synthesis for Spaceborne Array Antenna Based on Improved Whale Optimization Algorithm

Applied Sciences, 2023
For the purpose of fulfilling the low sidelobe level (SLL) requirements for spaceborne phased array antenna pattern synthesis, this paper proposes a new improved whale optimization algorithm (IWOA).
Hongming Hu, Huawang Li, Lulu Zhao, Xinglong Jiang, Jiashuo Yang, Yangyang Zhang   +5 more
doaj   +1 more source

A New Remote Sensing Change Detection Data Augmentation Method Based on Mosaic Simulation and Haze Image Simulation

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2023
The quality of optical remote sensing images is largely affected by clouds and haze. In addition, the mosaicking image of multiple remote sensing images, due to objective factors such as acquiring time or climate conditions, will lead to large spectral ...
Zhipan Wang, Di Liu, Zhongwu Wang, Xiang Liao, Qingling Zhang   +4 more
doaj   +1 more source

SiamHRnet-OCR: A Novel Deforestation Detection Model with High-Resolution Imagery and Deep Learning

Remote Sensing, 2023
Forests play a critical role in global carbon cycling, and continuous forest destruction together with other factors has accelerated global warming.
Zhipan Wang, Di Liu, Xiang Liao, Weihua Pu, Zhongwu Wang, Qingling Zhang   +5 more
doaj   +1 more source

A Combined Residual Detection Method of Reaction Wheel for Fault Detection

Shanghai Jiaotong Daxue xuebao, 2021
A fault detection method of combined residual is proposed to effectively master the health state of the reaction wheels of in-orbit satellite according to the telemetry data. Based on the characteristics of in-orbit telemetry data, in the proposed method,
HE Xiawei, CAI Yunze, YAN Lingling
doaj   +1 more source

Microsatellite Instability in Yeast: Dependence on the Length of the Microsatellite [PDF]

Genetics, 1997
One of the most common microsatellites in eukaryotes consists of tandem arrays [usually 15-50 base pairs (bp) in length] of the dinucleotide GT. We examined the rates of instability for poly GT tracts of 15, 33, 51, 99 and 105 bp in wild-type and mismatch repair-deficient strains of Saccharomyces cerevisiae. Rates of instability increased more than two
Monika Wierdl, Margaret Dominska, Thomas D. Petes   +2 more
openaire   +2 more sources

Progress in the Application of Immune Checkpoint Inhibitor-Based Immunotherapy for Targeting Different Types of Colorectal Cancer

Frontiers in Oncology, 2021
Colorectal cancer (CRC), a common malignant disease, has the second highest mortality rate among all cancer types. Due to the diversity and heterogeneity of CRC, few effective treatment strategies have been developed in recent years, except for surgical ...
Rui He, Yefang Lao, Wenyan Yu, Xiaohui Zhang, Min Jiang, Chunrong Zhu   +5 more
doaj   +1 more source

The death of a microsatellite: a phylogenetic perspective on microsatellite interruptions [PDF]

Molecular Biology and Evolution, 1999
Microsatellite mutations can be studied by direct observation in pedigrees (Weber and Wong 1993; Crawford and Cuthbertson 1996; Primmer et al. 1996), by sequencing alleles (Blanquer-Maumont and Crouau-Roy 1995; Estoup et al. 1995; Garza and Freimer 1996; Metzgar et al. 1998; Taylor, Sanny, and Breden 1999), and by mapping allele sizes or sequences onto
J. M. H. Durkin, Felix Breden, J. S. Taylor   +2 more
openaire   +2 more sources

Identification and validation of microsatellite markers in strawberry tree (Arbutusunedo L.) [PDF]

, 2019
Strawberry tree (Arbutus unedo L.), an evergreen shrub/small tree of the family Ericaceae, is a main constituent of the Mediterranean basin flora; although it is also found in southwestern Prance, Macaronesia, and Ireland. The small fruits are edible but
Carlier, Jorge, Fazenda, Pedro, Fonseca, Maria, Leitão, José, Pereira, Ricardo   +4 more
core   +1 more source

Microsatellite genotyping of apple (Malus × domestica Borkh.) genetic resources in the Netherlands: application in collection management and variety identification [PDF]

, 2010
A highly informative set of 16 microsatellite markers was used to fingerprint 695 apple accessions from eight Dutch collections. Among the total sample, 475 different genotypes were distinguished based on multi-locus microsatellite variation, revealing a
Ernsting, G., Houtman, H., Jongejans, B., Kemp, H., Treuren, R., van, Visser, L.   +5 more
core   +2 more sources