Results 1 to 10 of about 50,169 (235)
Editorial: Microsatellite and microsatellite instability
Frontiers in Genetics, 2023 Alexandre How-Kit +5 more
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IJU Case Reports, 2022 Introduction Prostate cancer with a microsatellite instability‐high or mismatch repair‐deficient status is not common. Few reports of the response to pembrolizumab in metastatic castration‐resistant prostate cancer in a real‐world setting have been ...
Takumi Kageyama +7 more
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Microsatellite instability-high gastric cancer patients may benefit from adjuvant radiotherapy
Libri Oncologici, 2023 Gastric cancer remains one of the deadliest types of cancer despite the improvements in therapy regimens. The knowledge about specific molecular and histopathologic features of gastric tumors leads toward targeted therapy protocols.
Suzana Janković +6 more
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Frontiers in Oncology, 2022 BackgroundThe detection of microsatellite instability in urologic cancers is rare, especially in metastatic, castration-resistant prostate cancer with neuroendocrine differentiation.Case presentationThis is a case of a 66-year-old Asian male patient with
Tsukasa Yoshida +8 more
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Biology Direct, 2022 Background Historically, the molecular classification of colorectal cancer (CRC) was based on the global genomic status, which identified microsatellite instability in mismatch repair (MMR) deficient CRC, and chromosomal instability in MMR proficient CRC.
Pasquale Sibilio +4 more
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Microsatellite instability states serve as predictive biomarkers for tumors chemotherapy sensitivity
iScience, 2023 Summary: There is an urgent need for markers to predict the efficacy of different chemotherapy drugs. Herein, we examined whether microsatellite instability (MSI) status can predict tumor multidrug sensitivity and explored the underlying mechanisms.
Taojun Ye +8 more
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Microsatellite Instability and Its Clinical Significance in Endometrial Carcinoma [PDF]
Zhongguo quanke yixue, 2022 BackgroundThe role of microsatellite instability in the progression of endometrial cancer, a common cancer in women, has obtained increasing attentions in recent years.
XIAO Jing, WU Ying
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Microsatellite Instability in Keratoacanthoma [PDF]
Cancer, 1995 Tumors from patients with hereditary nonpolyposis colorectal cancer (HNPCC) and from a subset of patients with the related Muir-Torre syndrome (MTS) exhibit a novel type of genomic instability known as microsatellite instability (MIN). In general, this form of genomic instability results from mutations that inactivate DNA mismatch repair genes.
K C, Halling +3 more
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Frontiers in Oncology, 2023 ObjectiveTo explore new biomarkers related to microsatellite instability in order to better predict prognosis and guide medication.MethodsThe “limma” R package was used to identify differentially expressed genes in GSE24514, and then weighted correlation
Shaorui Rui +6 more
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Microsatellite instability in sarcomas [PDF]
Annals of Surgical Oncology, 1998 Microsatellite instability (MIN) has been studied in a variety of carcinomas and gynecologic sarcomas, but never in musculoskeletal sarcomas.We evaluated 16 skeletal and soft tissue sarcomas at nine genetic loci from chromosomal regions 1q, 5q, 7q, 12p, 13q, 17p, 19q, and two at 11p--all potential regions of interest regarding musculoskeletal sarcomas ...
S S, Martin +4 more
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