Results 11 to 20 of about 62,250 (302)
Gastroenterology Review, 2016 Introduction: Colorectal medullary carcinoma (MC) is a rare subtype of poorly differentiated adenocarcinoma (PDA) with unclear prognostic significance.
Miguel A. Gómez-Álvarez +10 more
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Microsatellite instability in colorectal cancer [PDF]
Radiology and Oncology, 2011 Colorectal cancer (CRC) is the third most common cancer in the world. In 75% CRC develops sporadically, in 25% hereditary or as a consequence of inflammatory bowel disease. CRC carcinogenesis develops over many years. The cause of CRC in 85% is chromosomal instability (CIN) and in 15% microsatellite instability (MSI-H), where hereditary nonpolyposis ...
Horvat, Matej, Štabuc, Borut
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Microsatellite instability in colorectal cancer [PDF]
EXCLI journal, 2018 EXCLI Journal; 17:Doc159; ISSN 1611 ...
Nojadeh, Jafar Nouri +2 more
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Editorial: Microsatellite and microsatellite instability
Frontiers in Genetics, 2023 Alexandre How-Kit +5 more
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Instability in Pentanucleotide Markers in a Subset of Microsatellite Instability-High Colorectal Cancer [PDF]
Current OncologyMicrosatellite instability (MSI) testing is frequently used to screen patients for the early detection of Lynch syndrome, the most common hereditary colorectal cancer syndrome. MSI testing compares microsatellite repeat lengths in tumor DNA with those in
Ahmet Yilmaz +10 more
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Microsatellite Instability and Colorectal Cancer
Archives of Pathology & Laboratory Medicine, 2011 Context .—About 15% of colorectal cancers are characterized by genomic microsatellite instability, and of these, about 1 in 5 (2%–4% overall) are due to Lynch syndrome, a dominantly inherited condition predisposing the patient to cancers of multiple organ systems, including the gastrointestinal tract ...
Katherine B, Geiersbach +1 more
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Microsatellite instability [PDF]
Gut, 1999 Genetic perturbation has been implicated in the development of tumours since the turn of the century. Indeed, genetic instability of one sort or another may be considered to be a hallmark of cancer itself, and the discovery of microsatellite instability (
Frayling, Ian, I M FRAYLING
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Microsatellite instability in sarcomas [PDF]
Annals of Surgical Oncology, 1998 Microsatellite instability (MIN) has been studied in a variety of carcinomas and gynecologic sarcomas, but never in musculoskeletal sarcomas.We evaluated 16 skeletal and soft tissue sarcomas at nine genetic loci from chromosomal regions 1q, 5q, 7q, 12p, 13q, 17p, 19q, and two at 11p--all potential regions of interest regarding musculoskeletal sarcomas ...
S S, Martin +4 more
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Microsatellite Instability in Keratoacanthoma [PDF]
Cancer, 1995 Tumors from patients with hereditary nonpolyposis colorectal cancer (HNPCC) and from a subset of patients with the related Muir-Torre syndrome (MTS) exhibit a novel type of genomic instability known as microsatellite instability (MIN). In general, this form of genomic instability results from mutations that inactivate DNA mismatch repair genes.
K C, Halling +3 more
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IJU Case Reports, 2022 Introduction Prostate cancer with a microsatellite instability‐high or mismatch repair‐deficient status is not common. Few reports of the response to pembrolizumab in metastatic castration‐resistant prostate cancer in a real‐world setting have been ...
Takumi Kageyama +7 more
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