Results 171 to 180 of about 55,423 (289)

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

International Journal of Cancer, Volume 158, Issue 2, Page 314-332, 15 January 2026.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano, Tina Keshavarzian, Nadine Biernath, Annika Fendler, Maria de Santis, Joachim Weischenfeldt, Mathieu Lupien   +6 more
wiley   +1 more source

Microsatellite Instability Status and Mismatch Repair Defects Testing in Endometrial Cancer-Insights from the Multicenter E-PEC Trial. [PDF]

Diagnostics (Basel)
Eser B, Papior D, Salmanton-García J, Cornely OA, Morgenstern B, Herpel C, Radosa JC, Almuheimid A, Aktas B, Weydandt L, Wittenborn J, Meyer-Wilmes P, Friebe V, Leidinger C, Kimmig R, Thangarajah F.   +15 more
europepmc   +1 more source

Advances in immuno-oncology biomarkers for gastroesophageal cancer: Programmed death ligand 1, microsatellite instability, and beyond

, 2018
Emily M. Lin, Jun Gong, Samuel J. Klempner, Joseph Chao   +3 more
openalex   +2 more sources

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, Volume 20, Issue 1, Page 117-133, January 2026.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Immune Checkpoint Inhibition as a Novel Strategy for Microsatellite Instability-High Duodenal Adenocarcinoma: A Report of Three Cases. [PDF]

Surg Case Rep
Shirabe K, Kawazoe T, Harima T, Nambara S, Tsuda Y, Nakanoko T, Ando K, Oki E, Yoshizumi T.   +8 more
europepmc   +1 more source

Supplementary Data from Preoperative Chemoradiotherapy plus Nivolumab before Surgery in Patients with Microsatellite Stable and Microsatellite Instability–High Locally Advanced Rectal Cancer

, 2023
Hideaki Bando, Yuichiro Tsukada, Koji Inamori, Yosuke Togashi, Shohei Koyama, Daisuke Kotani, Shota Fukuoka, Satoshi Yuki, Yoshito Komatsu, Shigenori Homma, Akinobu Taketomi, Mamoru Uemura, Takeshi Kato, Makoto Fukui, Masashi Wakabayashi, Naoki Nakamura, Motohiro Kojima, Hiroshi Kawachi, Richard Kirsch, Tsutomu Yoshida, Yutaka Suzuki, Akihiro Sato, Hiroyoshi Nishikawa, Masaaki Ito, Takayuki Yoshino   +24 more
openalex   +1 more source

Implementing Immunoscore in colorectal cancer: lessons from cohort studies, limitations and barriers to adoption

The Journal of Pathology: Clinical Research, Volume 12, Issue 1, January 2026.
Abstract The Immunoscore (IS) quantifies the immune contexture of colorectal cancer (CRC) by measuring CD3+ and CD8+ T‐cell densities in the tumour centre and invasive margin, providing superior prognostic performance compared with TNM staging and mismatch‐repair (MMR) status alone.
Matthew SS Hsu, Suet Yi Leung
wiley   +1 more source

Microsatellite instability and its impact on nutritional and inflammatory profiles in colorectal cancer. [PDF]

World J Gastrointest Surg
Qu HD, Gao X, Xiao P, Jiao Y.
europepmc   +1 more source

Microsatellite instability in inflamed and non-neoplastic colonic mucosa in ulcerative colitis

, 2009
Özlen Atuğ, Mustafa Akkіprіk, Fatih Eren, Arzu Tiftikçi, Filiz Türe Özdemir, Faruk Aşıcıoğlu, Hülya Över Hamzaoğlu, Nurdan Tözün   +7 more
openalex   +1 more source

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

Annals of Clinical and Translational Neurology, Volume 13, Issue 1, Page 108-121, January 2026.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco, Mònica Roldán, Yalda Jamshidi, Ioannis Georvasilis, Rocío Jadraque Rodríguez, Reza Boostani, Ali Shoeibi, Lluís Armengol, Anna Codina, Ehsan Ghayoor Karimiani, Cristina Hernando‐Davalillo, Loreto Martorell, María Luisa Ramírez Almaraz, Jordi Muchart, Carlos Ortez, Andrés Nascimento, Roser Urreizti, Daniel Natera‐de Benito, Mercedes Serrano   +18 more
wiley   +1 more source