Results 131 to 140 of about 55,724 (327)

Application of a double-enrichment procedure for microsatellite isolation and the use of tailed primers for high throughput genotyping

Genetics and Molecular Biology, 2007
The number of microsatellite loci and their allelic diversity contribute to increase accuracy and informativity of genetic estimates, however, the isolation of microsatellite loci is not only laborious but also quite expensive.
Fábio Mendonça Diniz, Arati Iyengar, Paulo Sarmanho da Costa Lima, Norman Maclean, Paul Bentzen   +4 more
doaj   +1 more source

Mutation Rate in Human Microsatellites: Influence of the Structure and Length of the Tandem Repeat [PDF]

, 1998
Bernd Brinkmann, Michael Klintschar, Franz Neuhuber, J. Hühne, Burkhard Rolf   +4 more
openalex   +1 more source

Microsatellite polymorphism across the M. tuberculosis and M. bovis genomes: Implications on genome evolution and plasticity

BMC Genomics, 2006
Background Microsatellites are the tandem repeats of nucleotide motifs of size 1–6 bp observed in all known genomes. These repeats show length polymorphism characterized by either insertion or deletion (indels) of the repeat units, which in and around ...
Nagarajaram Hampapathalu A, Nagaraju Javaregowda, Kumar Pankaj, Sreenu Vattipally B   +3 more
doaj   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

International Journal of Cancer, EarlyView.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano, Tina Keshavarzian, Nadine Biernath, Annika Fendler, Maria de Santis, Joachim Weischenfeldt, Mathieu Lupien   +6 more
wiley   +1 more source

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

International Journal of Cancer, EarlyView.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert, Claire Vargas, Sina Jasmin Wille, Karsten Rippe   +3 more
wiley   +1 more source

Genetic diversity of the Italian thoroughbred horse population

Italian Journal of Animal Science, 2019
For over three centuries, thoroughbred (TB) horses have been selected exclusively for traits enhancing racing performances. Officially the TB origins can be genetically traced back along the male line due to the crossbreeding among 50 English royal mares
Mario Cosenza, Valentina La Rosa, Raffaella Rosati, Vincenzo Chiofalo   +3 more
doaj   +1 more source

Genome-wide identification of microsatellites in white clover (Trifolium repens L.) using FIASCO and phpSSRMiner

Plant Methods, 2008
Background Allotetraploid white clover (Trifolium repens L.) is an important forage legume widely cultivated in most temperate regions. Only a small number of microsatellite markers are publicly available and can be utilized in white clover breeding ...
Bouton Joseph H, Zhao Patrick X, He Ji, Zhang Yan, Monteros Maria J   +4 more
doaj   +1 more source

Microsatellite instability, MLH-1 promoter hypermethylation, and frameshift mutations at coding mononucleotide repeat microsatellites in ovarian tumors [PDF]

, 2001
Esther Gras, Lluís Catasús, Rosmary Arg�elles, Gema Moreno‐Bueno, José Palacios, Carlos Gamallo, Xavier Matías‐Guiu, Jaime Prat   +7 more
openalex   +1 more source

Molecular analysis of the evolutionary history of endometrial and ovarian carcinoma in Lynch syndrome

International Journal of Cancer, EarlyView.
What's New? Lynch syndrome is a prevalent cause of hereditary gynecological cancers, but the timeline of molecular alterations preceding malignancy remains unclear. By studying consecutive surveillance specimens for up to 15 years before cancer diagnosis, the authors found that atypical endometrial hyperplasia was indistinguishable from endometrial and
Anni K. Kauppinen, Alisa P. Olkinuora, Jukka‐Pekka Mecklin, Päivi T. Peltomäki   +3 more
wiley   +1 more source

SATIN: a micro and mini satellite mining tool of total genome and coding regions with analysis of perfect repeats polymorphism in coding regions

BMC Bioinformatics
Background Tandem repeats are specific sequences in genomic DNA repeated in tandem that are present in all organisms. Among the subcategories of TRs we have Satellite repeats, that is divided into macrosatellites, minisatellites, and microsatellites ...
Carlos Willian Dias Dantas, Sebastião Rodrigues da Costa Neto, Sandy Ingrid Aguiar Alves, Kenny da Costa Pinheiro, Edian Franklin Franco De Los Santos, Rommel Thiago Jucá Ramos   +5 more
doaj   +1 more source