BMC Genomics, 2018 Background Even though microsatellite loci frequently have been isolated using recently developed next-generation sequencing (NGS) techniques, this task is still difficult because of the subsequent polymorphism screening requires a substantial amount of ...
Yun Xia +4 more
doaj +1 more source
Identification and validation of microsatellite markers in strawberry tree (Arbutusunedo L.) [PDF]
, 2019 Strawberry tree (Arbutus unedo L.), an evergreen shrub/small tree of the family Ericaceae, is a main constituent of the Mediterranean basin flora; although it is also found in southwestern Prance, Macaronesia, and Ireland. The small fruits are edible but
Carlier, Jorge +4 more
core +1 more source
Frameshift mutations at coding mononucleotide repeat microsatellites in endometrial carcinoma with microsatellite instability [PDF]
Cancer, 2000 Microsatellite instability (MI) is a frequent occurrence in endometrioid carcinoma of the endometrium (EC). Several genes known to contain mononucleotide short tracts in their coding sequences (TGF-beta RII, IGFIIR, BAX, hMSH6, and hMSH3) are likely targets for mutations in these tumors.DNA from 24 patients with EC and MI was extracted from blood and ...
Lluis Catasus +6 more
openaire +3 more sources
, 2007 We propose a simple model of pathologic microsatellite expansion, and describe an inherent self-repairing mechanism working against expansion. We prove that if the probabilities of elementary expansions and contractions are equal, microsatellite ...
Amos +48 more
core +1 more source
Molecular cytogenetic differentiation of paralogs of Hox paralogs in duplicated and re-diploidized genome of the North American paddlefish (Polyodon spathula). [PDF]
, 2017 BackgroundAcipenseriformes is a basal lineage of ray-finned fishes and comprise 27 extant species of sturgeons and paddlefishes. They are characterized by several specific genomic features as broad ploidy variation, high chromosome numbers, presence of ...
Amemiya, Chris T +7 more
core +4 more sources
Repeat expansions confer WRN dependence in microsatellite-unstable cancers [PDF]
Nature, 2020 The RecQ DNA helicase WRN is a synthetic lethal target for cancer cells with microsatellite instability (MSI), a form of genetic hypermutability that arises from impaired mismatch repair1-4. Depletion of WRN induces widespread DNA double-strand breaks in MSI cells, leading to cell cycle arrest and/or apoptosis.
Niek van Wietmarschen +32 more
openaire +4 more sources
Development of Sequence Tagged Microsatellite Site (STMS) markers in Azalea [PDF]
A genomic library was constructed from DNA of two azalea genotypes: a Belgian pot azalea R. simsii hybrid Mevr. Van Belle and a Chinese R. simsii from Daoxian.
Arens, P. +5 more
core +2 more sources
Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites. [PDF]
, 2007 BACKGROUND: Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudescence, or reinfection.
Anderson, T J C +14 more
core +2 more sources
Quasimonomorphic Mononucleotide Repeats for High‐Level Microsatellite Instability Analysis [PDF]
Disease Markers, 2004 Microsatellite instability (MSI) analysis is becoming more and more important to detect sporadic primary tumors of the MSI phenotype as well as in helping to determine Hereditary Non‐Polyposis Colorectal Cancer (HNPCC) cases. After some years of conflicting data due to the absence of consensus markers for the MSI phenotype, a meeting held in Bethesda ...
Asad Umar +5 more
openaire +2 more sources
Microsatellite Markers for the New Zealand Endemic Tree Fuchsia excorticata (Onagraceae)
Applications in Plant Sciences, 2013 Premise of the study: Microsatellite markers were developed from a New Zealand endemic understory tree, Fuchsia excorticata, to investigate factors affecting the mating system.
Megan L. Van Etten +2 more
doaj +1 more source