Results 261 to 270 of about 48,754 (308)
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A new bovine dinucleotide repeat microsatellite: microsatellite INRA 18

Animal Genetics, 1993
An Anonymous clone containing a (TG)11 Microsatellites was isolated from a bovine genomic Sau3A size selected (approx.500pb) pGEM-4-Z library by hybridization to poly (dC-dT). Primers for polymerase chai reaction (PCR) were designed to amplify the region containing this microsatellite.
Moazami-Goudarzi, Katayoun   +3 more
openaire   +4 more sources

A new bovine dinucleotide repeat microsatellite: microsatellite INRA 30

Animal Genetics, 1993
"Chantier qualité spécifique "Auteurs Externes" département de Génétique animale : uniquement liaison auteur au référentiel HR-Access " ; International ...
Ciampolini, R.   +3 more
openaire   +3 more sources

Mutational Dynamics of Microsatellites

Molecular Biotechnology, 2009
Microsatellites are a ubiquitous class of simple repetitive DNA sequences, which are widespread in both eukaryotic and prokaryotic genomes. The use of microsatellites as polymorphic DNA markers has considerably increased both in the number of studies and in the number of organisms, primarily for genetic mapping, studying genomic instability in cancer ...
Atul, Bhargava, F F, Fuentes
openaire   +2 more sources

Cancer and forensic microsatellites

Forensic Science, Medicine, and Pathology, 2008
Although not directly related, circumstances do occur in forensic investigations whereby cancer studies and forensic science cross paths. This review takes a look at the circumstances under which this may occur, and investigates some potential problems that can arise when tumor tissue is submitted for DNA profile analysis.
Karen, Page, Eleanor A M, Graham
openaire   +2 more sources

Microsatellites: consensus and controversy

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2000
Microsatellite DNA loci have recently been adopted for many biological applications. Comparative studies across a wide range of species has revealed many details of their mutational properties and evolutionary life cycles. Experience shows that a full understanding of these processes is essential to ensure the effective use of microsatellites as ...
G K, Chambers, E S, MacAvoy
openaire   +2 more sources

Microsatellites

1998
Abstract Microsatellites are highly polymorphic DNA markers with discrete loci and co dominant alleles. They have a wide range of applications which previously were difficult to address experimentally. Microsatellites are almost uniformly distributed over the entire genome, which is what makes them so useful for genome mapping projects ...
openaire   +1 more source

Microsatellite Instability Testing

2003
Microsatellites are tandem repeats of simple sequences that occur abundantly and are randomly interspersed throughout the human genome. They typically consist of 10-50 copies of 1-6 bp motifs, and are characterized by a high degree of polymorphism. Despite the variability observed among individuals, microsatellite are replicated faithfully at each cell
Y R, Parc, K C, Halling
openaire   +2 more sources

Characterization of canine microsatellites

1993
Canine DNA was cloned in M13 and screened for the presence of (dC-dA)n.(dG-dT)n repeats. Oligonucleotide primers were synthesised to the microsatellite flanking sequences and used in the polymerase chain reaction to amplify those loci from genomic DNA. The polymorphism of each microsatellite was estimated in a set of unrelated dogs.
N G, Holmes   +5 more
openaire   +2 more sources

Microsatellite instability: an update

Archives of Toxicology, 2015
Deficient DNA mismatch repair (MMR) results in a strong mutator phenotype known as microsatellite instability (MSI), which is a hallmark of Lynch syndrome-associated cancers. MSI is characterized by length alterations within simple repeated sequences that are called microsatellites.
Hiroyuki, Yamamoto, Kohzoh, Imai
openaire   +2 more sources

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