Results 81 to 90 of about 73,898 (290)

Classification and unification of the microscopic deterministic traffic models [PDF]

open access: yesPhysical Review E, 2015
We identify a universal mathematical structure in microscopic deterministic traffic models (with identical drivers), and thus we show that all such existing models in the literature, including both the two-phase and three-phase models, can be understood as special cases of a master model by expansion around a set of well-defined ground states.
Bo, Yang, Christopher, Monterola
openaire   +2 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Using Probe Counts to Provide High-Resolution Detector Data for a Microscopic Traffic Simulation

open access: yesVehicles
Microscopic traffic simulations have become increasingly important for research targeting connected vehicles. They are especially appreciated for enabling investigations targeting large areas, which would be practically impossible or too expensive in the
Tobias Veihelmann   +3 more
doaj   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan   +22 more
wiley   +1 more source

SUMO in SPACE: Combining SUMO and dSPACE for Advanced Traffic Simulation

open access: yesSUMO Conference Proceedings
Microscopic traffic simulation tools enable the simulation of various traffic demands and their impacts. By implementing realistic traffic models, they are commonly used to analyze traffic engineering measures.
Christopher Stang, Dennis Roeser
doaj   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Towards microscopic models for bicycle traffic simulation

open access: yes, 2023
As bicycling becomes an integral part of sustainable mobility, it becomes essential to enhance planning strategies that ensure bicycling as an efficient mode of transport. While traffic simulation has been extensively utilized for traffic planning of various modes of transport, this type of modeling support is largely lacking in the planning of bicycle
openaire   +3 more sources

Two-lane traffic rules for cellular automata: A systematic approach

open access: yes, 1997
Microscopic modeling of multi-lane traffic is usually done by applying heuristic lane changing rules, and often with unsatisfying results. Recently, a cellular automaton model for two-lane traffic was able to overcome some of these problems and to ...
B. Eisenblätter   +32 more
core   +2 more sources

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

From traffic and pedestrian follow-the-leader models with reaction time to first order convection-diffusion flow models

open access: yes, 2016
In this work, we derive first order continuum traffic flow models from a microscopic delayed follow-the-leader model. Those are applicable in the context of vehicular traffic flow as well as pedestrian traffic flow.
Costeseque, Guillaume   +3 more
core  

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