Results 131 to 140 of about 32,983 (314)

Some chemical components of mitochondria and microsomes from germinating castor beans [PDF]

, 1957
Takashi Akazawa, Harry Beevers
openalex   +1 more source

The photochemical action spectrum of the carbon monoxide inhibited hydroxylation of cyclohexane by rat liver microsomes [PDF]

, 1969
H. Diehl, S Căpâlnă, V. Ullrich
openalex   +1 more source

Preparation of ribosome-free membranes from rat liver microsomes by means of lithium chloride [PDF]

, 1969
Timothy Scott‐Burden, Å.O. Hawtrey
openalex   +1 more source

Metabolism of polycyclic compounds. 26. The hydroxylation of some aromatic hydrocarbons by the ascorbic acid model hydroxylating system and by rat-liver microsomes [PDF]

, 1964
E. Boyland, Masayuki Kimura, Peter Sims
openalex   +1 more source

Toxicological Response of the BEAS‐2B Cell After Acute Exposure at the Air–Liquid Interface to Ethylbenzene and m‐Xylene Alone and in Binary Mixtures

Journal of Applied Toxicology, EarlyView.
ABSTRACT Benzene, toluene, ethylbenzene, and xylenes (o‐, m‐, and p‐xylenes) constitute a family, named BTEX, of volatile organic compounds (VOCs) known for its toxicity. This study aimed to study the acute in vitro toxicity of ethylbenzene and m‐xylene on human bronchial epithelial cells exposed at the air–liquid interface (ALI).
Nour Jaber, Claude Emond, Fabrice Cazier, Sylvain Billet   +3 more
wiley   +1 more source

In Vitro and Clinical Evaluations of UGT1A1‐, P‐gp‐, OATP1B1‐, and BCRP‐Mediated Drug–Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor

The Journal of Clinical Pharmacology, EarlyView.
Abstract Belumosudil is an oral selective rho‐associated coiled‐coil containing protein kinase 2 inhibitor, approved as a treatment for chronic graft‐versus‐host disease. Prior clinical studies demonstrated that coadministration with strong CYP3A4 inducers or proton pump inhibitors requires dose modification of belumosudil.
Olivier Schueller, Lauren Lohmer, Felix Beck, Jeegar Patel, Jasminder Sahi   +4 more
wiley   +1 more source

The lipid composition of rat-liver mitochondria, fluffy layer and microsomes [PDF]

, 1962
GS Getz, W Bartley, Fiorenzo Stirpe, BM NOTTON, Andrew A. Renshaw   +4 more
openalex   +1 more source

Physiologically Based Pharmacokinetic (PBPK) Model to Predict the Magnitude of Drug–Drug Interaction Between Fezolinetant and CYP1A2 Inhibitors

The Journal of Clinical Pharmacology, EarlyView.
Abstract Fezolinetant is a non‐hormonal, selective neurokinin 3 receptor antagonist approved in multiple countries including the United States, in Europe, and in Asia for the treatment of moderate to severe vasomotor symptoms in menopausal women. Fezolinetant is primarily metabolized by CYP1A2 and was found to be a sensitive substrate for CYP1A2 ...
Mary P. Choules, Yukio Otsuka, Jace C. Nielsen, Megumi Iwai, Peter L. Bonate   +4 more
wiley   +1 more source

Polyribonucleotide synthesis by subfractions of microsomes from rat liver [PDF]

, 1968
Neil Wilkie, R.M.S. Smellie
openalex   +1 more source

Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta, Matt Hall, Benjamin Masserano, Averi Wilson, Katherine Johnson, Clifford Chen, Lasya Challa, Harita Katragadda, Vineeta Mittal   +8 more
wiley   +1 more source