Results 11 to 20 of about 50,037 (190)
New antibacterial agents and agent combinations are urgently needed to combat antimicrobial resistance. A multidimensional chemical library screening strategy was used to identify compounds in the National Cancer Institute (NCI) diversity set V library ...
Shivani Gargvanshi+3 more
doaj +1 more source
Microsomes, Microsomal Phospholipids, and Fatty Acid Synthesis [PDF]
Abstract The effect of microsomes on fatty acid synthesis by the soluble fraction of rat liver cells has been studied. It was shown that the microsomes contain a heat-labile inhibitory factor, presumably ATPase, and a heat-stable stimulatory factor.
Daniel W. Foster, William P. McWhorter
openaire +2 more sources
The use of in vitro in vivo extrapolation (IVIVE) from human hepatocyte (HH) and human liver microsome (HLM) stability assays is a widely accepted predictive methodology for human metabolic clearance (CLmet).
B. Williamson+2 more
semanticscholar +1 more source
The synergistic effect of daidzein and α-tocopherol or ascorbic acid on microsome and LDL oxidation
Isoflavone daidzein brings potential health benefits. Its antioxidant properties are considered to be responsible in part for its protective effects.
Heya Wang+2 more
doaj +1 more source
Phenylpropanoid-enriched broccoli seedling extract can reduce inflammatory markers and pain behavior
Background Pain is a worldwide problem requiring an effective, affordable, non-addictive therapy. Using the edible plant broccoli, a growth protocol was developed to induce a concentrated combinatorial of potential anti-inflammatories in seedlings ...
Aleksandra A. Gurgul+6 more
doaj +1 more source
Biotransformation of Liquiritigenin into Characteristic Metabolites by the Gut Microbiota
The bioavailability of flavonoids is generally low after oral administration. The metabolic transformation of flavonoids by the gut microbiota may be one of the main reasons for this, although these metabolites have potential pharmacological activities ...
Adili Keranmu+13 more
doaj +1 more source
Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.
About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple Salmonella/microsome test.
J. McCann, E. Choi, E. Yamasaki, B. Ames
semanticscholar +1 more source
Evaluation of Liver Microsomes for Genotoxicity Sensors—Voltammetry of the Microsomes [PDF]
The 2007 Joseph W.
James F. Rusling, Sadagopan Krishnan
openaire +2 more sources
The drug salinomycin (SAL) is a polyether antibiotic and used in veterinary medicine as coccidiostat and growth promoter. Recently, SAL was suggested as a potential anticancer drug.
Lisa Knoche+3 more
doaj +1 more source
Improvement of the solubilization of proteins in two-dimensional electrophoresis with immobilized pH gradients [PDF]
Membrane and nuclear proteins of poor solubility have been separated by high resolution two-dimensional (2-D) gel electrophoresis. Isoelectric focusing with immobilized pH gradients leads to severe quantitative losses of proteins in the resulting 2-D map, although the resolution is usually high.
arxiv +1 more source