Results 11 to 20 of about 11,599 (234)

Phenylpropanoid-enriched broccoli seedling extract can reduce inflammatory markers and pain behavior

open access: yesJournal of Translational Medicine, 2023
Background Pain is a worldwide problem requiring an effective, affordable, non-addictive therapy. Using the edible plant broccoli, a growth protocol was developed to induce a concentrated combinatorial of potential anti-inflammatories in seedlings ...
Aleksandra A. Gurgul   +6 more
doaj   +1 more source

The synergistic effect of daidzein and α-tocopherol or ascorbic acid on microsome and LDL oxidation

open access: yesCzech Journal of Food Sciences, 2010
Isoflavone daidzein brings potential health benefits. Its antioxidant properties are considered to be responsible in part for its protective effects.
Heya Wang   +2 more
doaj   +1 more source

Microsomes, Microsomal Phospholipids, and Fatty Acid Synthesis

open access: yesJournal of Biological Chemistry, 1969
Abstract The effect of microsomes on fatty acid synthesis by the soluble fraction of rat liver cells has been studied. It was shown that the microsomes contain a heat-labile inhibitory factor, presumably ATPase, and a heat-stable stimulatory factor.
D W, Foster, W P, McWhorter
openaire   +2 more sources

Influence of major structural features of tocopherols and tocotrienols on their ω-oxidation by tocopherol-ω-hydroxylase

open access: yesJournal of Lipid Research, 2007
Human cytochrome P450 4F2 (CYP4F2) catalyzes the initial ω-hydroxylation reaction in the metabolism of tocopherols and tocotrienols to carboxychromanols and is, to date, the only enzyme shown to metabolize vitamin E.
Timothy J. Sontag, Robert S. Parker
doaj   +1 more source

ACBP and cholesterol differentially alter fatty acyl CoA utilization by microsomal ACAT

open access: yesJournal of Lipid Research, 2003
Microsomal acyl CoA:cholesterol acyltransferase (AC57) is stimulated in vitro and/or in intact cells by proteins that bind and transfer both substrates, cholesterol, and fatty acyl CoA.
Hsu Chao   +4 more
doaj   +1 more source

Biotransformation of Liquiritigenin into Characteristic Metabolites by the Gut Microbiota

open access: yesMolecules, 2022
The bioavailability of flavonoids is generally low after oral administration. The metabolic transformation of flavonoids by the gut microbiota may be one of the main reasons for this, although these metabolites have potential pharmacological activities ...
Adili Keranmu   +13 more
doaj   +1 more source

Evaluation of Betulin Mutagenicity by Salmonella/Microsome Test [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2016
Purpose: Betulin is a pentacyclic triterpene found in the outer barks of innumerous plants. This secondary metabolite is easily isolated from plants with the major interest in converting it to betulinic acid, which pharmacological properties were much ...
Edson Hideaki Yoshida   +5 more
doaj   +1 more source

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren   +4 more
wiley   +1 more source

LC-HRMS-Based Identification of Transformation Products of the Drug Salinomycin Generated by Electrochemistry and Liver Microsome

open access: yesAntibiotics, 2022
The drug salinomycin (SAL) is a polyether antibiotic and used in veterinary medicine as coccidiostat and growth promoter. Recently, SAL was suggested as a potential anticancer drug.
Lisa Knoche   +3 more
doaj   +1 more source

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan   +22 more
wiley   +1 more source

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