Results 21 to 30 of about 22,884 (277)

Effects of Kaempferia galanga L. and ethyl-p-methoxycinnamate (EPMC) [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2011
Kaempferia galanga L. (K. galanga L.), belonging to the Zingiberaceae family, has been widely used in Thai traditionalmedicine for treatment of hypertension, asthma, rheumatism, indigestion, cold and headache and relief abdominal pain.This study aimed to
Wanna Sirisangtragul   +1 more
doaj  

Stem Microsome Preparation and Mannan Synthase Activity Assay

open access: yesBio-Protocol, 2013
Mannans are hemicellulosic polysaccharides and are present in cell walls of all land plants. Mannan polysaccharides are synthesized by two enzymes, mannan synthase (ManS) for backbone (mannan or glucomannan) synthesis and galactomannan galactosyl ...
Yan Wang
doaj   +1 more source

Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and Their Mutagenic Activity

open access: yesMolecules, 2012
A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds.
Wagner Vilegas   +6 more
doaj   +1 more source

The composition of rat liver microsomes. The structural proteins of rat liver microsomes [PDF]

open access: yesBiochemical Journal, 1969
1. The structural-protein component of microsomal membranes was isolated by three separate methods. Analysis by polyacrylamide-gel electrophoresis indicated that the microsomal structural component is made up of a heterogeneous group of proteins. These proteins were further characterized by their phospholipid-binding capacity.
J. K. Pollak, K. A. Ward
openaire   +3 more sources

Assessment of Metabolic Interaction between Repaglinide and Quercetin via Mixed Inhibition in the Liver: In Vitro and In Vivo

open access: yesPharmaceutics, 2021
Repaglinide (RPG), a rapid-acting meglitinide analog, is an oral hypoglycemic agent for patients with type 2 diabetes mellitus. Quercetin (QCT) is a well-known antioxidant and antidiabetic flavonoid that has been used as an important ingredient in many ...
Ji-Min Kim   +4 more
doaj   +1 more source

Changes of microsomal membrane compositions modulate microsomal enzyme activity [PDF]

open access: yesPediatric Research, 1979
We have shown previously, that the activity of cerebrosulfotransferase (CST) a microsomal enzyme involved in myelin synthesis is modulated in vitro by the cholesterol-phospholipid ratio (C/P) in microsomal membranes. To further investigate this mechanism, we studied two different models: 1.) Removal of cholesterol by phospholipid micelles and 2 ...
H. Jutzi   +3 more
openaire   +2 more sources

Analyses of CYP2C in Porcine Microsomes [PDF]

open access: yesBasic & Clinical Pharmacology & Toxicology, 2008
Abstract: The cytochrome P450 2C (CYP2C) subfamily in human beings includes four different isoenzymes that metabolize different substrates although with some cross reactivity. Some of these substrates (e.g. diclofenac and tolbutamide), have been investigated in porcine microsomes, but without identifying the specific CYP catalysing the reactions.
Skaanild, Mette Tingleff   +1 more
openaire   +5 more sources

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Liver kidney microsome antibodies. Analysis of a laboratory series

open access: yesPractical Laboratory Medicine, 2023
Objectives: The objectives were to characterize the liver kidney microsome (LKM) antibody profile of a 14-month-old girl with autoimmune hepatitis and analyze the laboratory prevalence of LKM positivity. Design and methods: This is retrospective analysis
Sandra Sanchez   +6 more
doaj  

Characterization and Quantification of the Compounds of the Ethanolic Extract from Caesalpinia ferrea Stem Bark and Evaluation of Their Mutagenic Activity

open access: yesMolecules, 2014
Caesalpinia ferrea Martius has traditionally been used in Brazil for many medicinal purposes, such as the treatment of bronchitis, diabetes and wounds.
Carlos César Wyrepkowski   +7 more
doaj   +1 more source

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