Results 21 to 30 of about 50,037 (190)
The characterization of novel radiotracers toward their metabolic stability is an essential part of their development. While in vitro methods such as liver microsome assays or ex vivo blood or tissue samples provide information on overall stability ...
Sandy Lemm+6 more
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The plant endomembrane system plays vital roles for synthesis, modification and secretion of proteins and lipids. From the classic view, only mRNAs encoding secreted proteins could be targeted to the endoplasmic reticulum (ER) for translation via a co ...
Yonghui Zhao, Shengben Li
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About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple Salmonella/microsome test.
J. McCann, B. Ames
semanticscholar +1 more source
Most of commercially important crops, including maize and common bean, are sensitive to water deficit and salinity. Polyamines are considered to be osmotic and salt tolerance modulators and biochemical indicators of these stresses.
J. Legocka, E. Sobieszczuk-Nowicka
semanticscholar +1 more source
Effects of Kaempferia galanga L. and ethyl-p-methoxycinnamate (EPMC) [PDF]
Kaempferia galanga L. (K. galanga L.), belonging to the Zingiberaceae family, has been widely used in Thai traditionalmedicine for treatment of hypertension, asthma, rheumatism, indigestion, cold and headache and relief abdominal pain.This study aimed to
Wanna Sirisangtragul+1 more
doaj
A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds.
Wagner Vilegas+6 more
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Repaglinide (RPG), a rapid-acting meglitinide analog, is an oral hypoglycemic agent for patients with type 2 diabetes mellitus. Quercetin (QCT) is a well-known antioxidant and antidiabetic flavonoid that has been used as an important ingredient in many ...
Ji-Min Kim+4 more
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The composition of rat liver microsomes. The structural proteins of rat liver microsomes [PDF]
1. The structural-protein component of microsomal membranes was isolated by three separate methods. Analysis by polyacrylamide-gel electrophoresis indicated that the microsomal structural component is made up of a heterogeneous group of proteins. These proteins were further characterized by their phospholipid-binding capacity.
J. K. Pollak, K. A. Ward
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Changes of microsomal membrane compositions modulate microsomal enzyme activity [PDF]
We have shown previously, that the activity of cerebrosulfotransferase (CST) a microsomal enzyme involved in myelin synthesis is modulated in vitro by the cholesterol-phospholipid ratio (C/P) in microsomal membranes. To further investigate this mechanism, we studied two different models: 1.) Removal of cholesterol by phospholipid micelles and 2 ...
H. Jutzi+3 more
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Sixty‐five patients with histologically proven chronic active hepatitis of unknown cause but associated with the antiliver/kidney microsome antibody type 1, confirmed by immunofluorescence and immunoprecipitation, were selected as forming a special ...
J. Homberg+13 more
semanticscholar +1 more source