The antimutagenic effect of monoterpenes against UV-irradiation-, 4NQO- and t-BOOH-induced mutagenesis in coli [PDF]
The aim of this work was to investigate the antimutagenic potential of monoterpenes from sage and basil in Escherichia coli. The mutagenic potential of monoterpenes was pre-screened with Salmonella/microsome reversion assay in strain TA100 and no ...
Nikolić Biljana+3 more
doaj +1 more source
Liver/kidney microsome antibody type 1 and hepatitis C virus infection
Recent studies have shown that hepatitis C virus antibodies are present in a large proportion of patients with autoimmune hepatitis type 2. We have studied 83 patients with liver/kidney microsome antibody‐positive type 1 hepatitis.
F. Lunel+11 more
semanticscholar +1 more source
Genotoxicity of plant extracts
Aqueous extracts of seven species used in Brazilian popular medicine (Achyrocline satureoides, Iodina rhombifolia, Desmodium incanum, Baccharis anomala, Tibouchina asperior, Luehea divaricata, Maytenus ilicifolia) were screened to the presence of ...
Vera M. F. Vargas+2 more
doaj +1 more source
Statistical analysis of the Ames Salmonella/microsome test.
A family of statistical models for analysis of Ames Salmonella/microsome test data is constructed that considers mutation and toxicity as competing risks and allows hyper-Poisson variability.
B. Margolin, N. Kaplan, E. Zeiger
semanticscholar +1 more source
ACBP and cholesterol differentially alter fatty acyl CoA utilization by microsomal ACAT
Microsomal acyl CoA:cholesterol acyltransferase (AC57) is stimulated in vitro and/or in intact cells by proteins that bind and transfer both substrates, cholesterol, and fatty acyl CoA.
Hsu Chao+4 more
doaj
Abnormal subcellular distribution of GLUT4 protein in obese and insulin-treated diabetic female dogs
The GLUT4 transporter plays a key role in insulin-induced glucose uptake, which is impaired in insulin resistance. The objective of the present study was to investigate the tissue content and the subcellular distribution of GLUT4 protein in 4- to 12-year-
A.M. Vargas+5 more
doaj +1 more source
Smooth microsomes. a trap for cholesteryl ester formed in hepatic microsomes.
Acyl-CoA:cholesterol acyltransferase was found predominantly (85%) in RNA-rich microsomes, the rest being in RNA-poor and smooth microsomes. However, the esterified cholesterol concentration of smooth microsomes was 2-fold greater than that of RNA-rich microsomes, suggesting the possibility of an interaction between RNA-rich and smooth microsomes.
S Hashimoto, A M Fogelman
openaire +3 more sources
Human cytochrome P450 4F2 (CYP4F2) catalyzes the initial ω-hydroxylation reaction in the metabolism of tocopherols and tocotrienols to carboxychromanols and is, to date, the only enzyme shown to metabolize vitamin E.
Timothy J. Sontag, Robert S. Parker
doaj
Antimutagenic effect of essential oil of sage (Salvia officinalis L.) and its fractions against UV-induced mutations in bacterial and yeast cells [PDF]
The inhibition of spontaneous and UV-induced mutations by essential oil (EO) of sage (Salvia officinalis L.) and its fractions F1-F5 containing different proportions of mono- and sesquiterpenes was studied with the Salmonella/microsome, E.
Knežević-Vukčević Jelena B.+5 more
doaj +1 more source
Antimutagenic activity of extracts of natural substances in the Salmonella/microsome assay.
Scientific information regarding plants used in folk medicine in the form of teas and their effect on human health or on genetic material has been the subject of many different types of investigation.
R. C. Horn, V. M. Vargas
semanticscholar +1 more source