Results 41 to 50 of about 74,782 (341)

Changes of microsomal membrane compositions modulate microsomal enzyme activity [PDF]

Pediatric Research, 1979
We have shown previously, that the activity of cerebrosulfotransferase (CST) a microsomal enzyme involved in myelin synthesis is modulated in vitro by the cholesterol-phospholipid ratio (C/P) in microsomal membranes. To further investigate this mechanism, we studied two different models: 1.) Removal of cholesterol by phospholipid micelles and 2 ...
H. Jutzi, Norbert Herschkowitz, Ulrich N. Wiesmann, H P Siegrist   +3 more
openaire   +2 more sources

Original Article [PDF]

, 2016
The pancreas taken from the frog (Rana nigromaculata) was fixed in 1% OsO_4 and sliced into ultrathin sections for electron microscopic studies. The following observations were made: 1.
A Albini, A Cafaro, A Guihot, A Herasimtschuk, A Lind, A Poggi, A Sáez-Cirión, AG Fisher, AH Rosenberg, AI Dayton, AN Phillips, Angela Arancio, Anna Casabianca, Antonella Tripiciano, AO Pasternak, Aurelio Cafaro, B Berkhout, B Ensoli, B Ensoli, B Ensoli, B Ensoli, B Ensoli, B Ensoli, B Ensoli, B Grinsztejn, B Marin, Barbara Collacchi, Barbara Ensoli, Bennett Asia, C Chiozzini, Cecilia Sgadari, CJ Achenbach, CJ Li, CJ Li, CT Costiniuk, Daniel Joffe, DG Stupack, E Chertova, E Fanales-Belasio, E Fanales-Belasio, E Ruoshlati, E Toschi, E Vardas, E Wood, E Wood, Elise Levendal, EM Faller, Enrico Garaci, F Ensoli, F García, F García, F Lori, F Nicoli, F Rayne, F Sforza, Fabrizio Ensoli, FW Studier, FW Studier, G Barillari, G Barillari, G Cenderello, G Goldstein, G Hardy, G Marchetti, G Mirani, G Rezza, G Scala, G Zauli, Giovanni Paniccia, GJ Besson, GM Lucas, GR Campbell, GR Campbell, HC Chang, I Ketseoglou, J Hauber, J Neuhaus, J Schouten, JC Li, JC Li, JL Turner, John Velaphi Ndimande, KT Jeang, L Buonaguro, L Gazzola, L Hocqueloux, L Huang, Lara Tavoschi, LS Weinberger, M Massanella, M Matsui, M Medina-Ramírez, M Ott, MA French, Maphoshane Nchabeleng, Maria Rosaria Pavone Cossut, Mauro Magnani, MC Re, MJ Buzón, MJ Kozal, MM Lederman, MO Westendorp, MW Richardson, N Kim, O Longo, Olimpia Longo, Orietta Picconi, P Monini, P Reiss, Paolo Monini, PW Hunt, R Gavioli, R Planès, R Planès, RE Barth, RK Gupta, RP Viscidi, S Bellino, S Buttò, S Debaisieux, S Gupta, S Hua, S Mediouni, S Rosen, SA Migueles, SM Cheng, Sonia Moretti, Stefania Bellino, Stefano Buttò, T Demberg, TH Burdo, TP Johnson, Vittorio Francavilla, W Chantratita, Y Wu, Yogan Pillay   +135 more
core   +6 more sources

Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and Their Mutagenic Activity

Molecules, 2012
A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds.
Wagner Vilegas, Lourdes Campaner dos Santos, Paulo Takeo Sano, Samara Fernandes de Souza, Eliana Aparecida Varanda, Paula Karina Boldrin, Fabiana Volpe Zanutto   +6 more
doaj   +1 more source

Assessment of Metabolic Interaction between Repaglinide and Quercetin via Mixed Inhibition in the Liver: In Vitro and In Vivo

Pharmaceutics, 2021
Repaglinide (RPG), a rapid-acting meglitinide analog, is an oral hypoglycemic agent for patients with type 2 diabetes mellitus. Quercetin (QCT) is a well-known antioxidant and antidiabetic flavonoid that has been used as an important ingredient in many ...
Ji-Min Kim, Seong-Wook Seo, Dong-Gyun Han, Hwayoung Yun, In-Soo Yoon   +4 more
doaj   +1 more source

Analyses of CYP2C in Porcine Microsomes [PDF]

Basic & Clinical Pharmacology & Toxicology, 2008
Abstract: The cytochrome P450 2C (CYP2C) subfamily in human beings includes four different isoenzymes that metabolize different substrates although with some cross reactivity. Some of these substrates (e.g. diclofenac and tolbutamide), have been investigated in porcine microsomes, but without identifying the specific CYP catalysing the reactions.
Skaanild, Mette Tingleff, Friis, Christian   +1 more
openaire   +5 more sources

Evaluation the inhibitory effect of nicardipine on the metabolism of quetiapine

Frontiers in Pharmacology
The aim of this study was to investigate the impact of calcium channel blockers (CCBs) and antihypertensive traditional Chinese medicine (TCM) on the metabolism of quetiapine. In vitro, two incubation systems of rat liver microsomes (RLM) and human liver
Jinzhao Yang, Hailun Xia, Qingqing Li, Ruibin Li, Lu Cao, Congrong Tang   +5 more
doaj   +1 more source

Effects of Kaempferia galanga L. and ethyl-p-methoxycinnamate (EPMC) [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2011
Kaempferia galanga L. (K. galanga L.), belonging to the Zingiberaceae family, has been widely used in Thai traditionalmedicine for treatment of hypertension, asthma, rheumatism, indigestion, cold and headache and relief abdominal pain.This study aimed to
Wanna Sirisangtragul, Bungorn Sripanidkulchai   +1 more
doaj  

Characterization and Quantification of the Compounds of the Ethanolic Extract from Caesalpinia ferrea Stem Bark and Evaluation of Their Mutagenic Activity

Molecules, 2014
Caesalpinia ferrea Martius has traditionally been used in Brazil for many medicinal purposes, such as the treatment of bronchitis, diabetes and wounds.
Carlos César Wyrepkowski, Daryne Lu Maldonado Gomes da Costa, Adilson Paulo Sinhorin, Wagner Vilegas, Rone Aparecido De Grandis, Flavia Aparecida Resende, Eliana Aparecida Varanda, Lourdes Campaner dos Santos   +7 more
doaj   +1 more source

DNA adducts in fish following an oil spill exposure [PDF]

, 2006
On 12 December 1999, one third of the load of the Erika tanker, amounting to about 10,000 t crude oil flowed into sea waters close to the French Atlantic Coast.
A. Amat, A. Pfohl-Leszkowicz, B French, B Kurelec, B Kurelec, BP Lyons, BP Lyons, C Genevois, CA Rice, D Petrapiana, DH Phillips, DH Phillips, E Aas, E Randerath, EJ Stein, F Telli-Karakok, F Vincent, FJ Van Schooten, G Ericson, G Ericson, G Ericson, JS Harvey, K Boillot, L Mazeas, LD Peters, M. Castegnaro, MC Poirier, MM Bradford, MS Myers, PAEL Schilderman, PC Baumann, R Amara, RA Lyons, T Burgeot, T. Burgeot, U Varanasi, WL Reichert   +36 more
core   +1 more source

Blue rayon e teste Salmonella/microssoma na avaliação da qualidade de águas costeiras Blue rayon and Salmonella/microsome assay in the evaluation of coastal water quality

Revista de Saúde Pública, 2006
OBJETIVO: Desenvolver estratégia para o monitoramento passivo das águas do estuário de Santos quanto à presença de atividade genotóxica e de hidrocarbonetos policíclicos aromáticos. MÉTODOS: Estudo realizado no estuário de Santos, Estado de São Paulo, em
Fábio Kummrow, Dulce Magalhães, Alexandre Franco, Gisela de Aragão Umbuzeiro   +3 more
doaj   +1 more source