Results 1 to 10 of about 47,963 (298)
Microsomes, Microsomal Phospholipids, and Fatty Acid Synthesis [PDF]
Journal of Biological Chemistry, 1969 Abstract The effect of microsomes on fatty acid synthesis by the soluble fraction of rat liver cells has been studied. It was shown that the microsomes contain a heat-labile inhibitory factor, presumably ATPase, and a heat-stable stimulatory factor.
Daniel W. Foster, William P. McWhorter
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Evaluation of Liver Microsomes for Genotoxicity Sensors—Voltammetry of the Microsomes [PDF]
The Electrochemical Society Interface, 2007 The 2007 Joseph W.
James F. Rusling, Sadagopan Krishnan
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The composition of rat liver microsomes. The structural proteins of rat liver microsomes [PDF]
Biochemical Journal, 1969 1. The structural-protein component of microsomal membranes was isolated by three separate methods. Analysis by polyacrylamide-gel electrophoresis indicated that the microsomal structural component is made up of a heterogeneous group of proteins. These proteins were further characterized by their phospholipid-binding capacity.
J. K. Pollak, K. A. Ward
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Changes of microsomal membrane compositions modulate microsomal enzyme activity [PDF]
Pediatric Research, 1979 We have shown previously, that the activity of cerebrosulfotransferase (CST) a microsomal enzyme involved in myelin synthesis is modulated in vitro by the cholesterol-phospholipid ratio (C/P) in microsomal membranes. To further investigate this mechanism, we studied two different models: 1.) Removal of cholesterol by phospholipid micelles and 2 ...
H. Jutzi +3 more
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Analyses of CYP2C in Porcine Microsomes [PDF]
Basic & Clinical Pharmacology & Toxicology, 2008 Abstract: The cytochrome P450 2C (CYP2C) subfamily in human beings includes four different isoenzymes that metabolize different substrates although with some cross reactivity. Some of these substrates (e.g. diclofenac and tolbutamide), have been investigated in porcine microsomes, but without identifying the specific CYP catalysing the reactions.
Skaanild, Mette Tingleff +1 more
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Smooth microsomes. a trap for cholesteryl ester formed in hepatic microsomes.
Journal of Biological Chemistry, 1980 Acyl-CoA:cholesterol acyltransferase was found predominantly (85%) in RNA-rich microsomes, the rest being in RNA-poor and smooth microsomes. However, the esterified cholesterol concentration of smooth microsomes was 2-fold greater than that of RNA-rich microsomes, suggesting the possibility of an interaction between RNA-rich and smooth microsomes.
S Hashimoto, A M Fogelman
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Microsome Isolation from Tissue
BIO-PROTOCOL, 2014 This protocol details the extraction of microsomes from frozen tissue in order to further examine the protein-protein interactions occurring within the endoplasmic reticulum. This protocol was adapted from Abisambra et al. (2013) with modifications made in order to optimize for subsequent use.
Maria Bodero, Jose F. Abisambra
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Microsomal epoxide hydrolase polymorphisms
Molecular Medicine Reports, 2010 Microsomal epoxide hydrolase plays a dual role in the activation and detoxification of carcinogenic compounds. Two polymorphic sites have been described in exons 3 and 4 of the microsomal epoxide hydrolase gene that change tyrosine residue 113 to histidine (Tyr113His) and histidine 139 to arginine (His139Arg), respectively.
Pinarbasi, Hatice +2 more
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Microsomes are the in vitro ER
The Journal of Cell Biology, 2005 ![Graphic][1] Microsomes (here) and ER look similar, and both have ribosomes (see dots near “ob2”). PALADEThe abundance of electron microscope (EM) images in the 1940s and 1950s brought a new problem: nomenclature. What to call all those black smudges?
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A Microsomal Nucleoside Diphosphatase
Journal of Biological Chemistry, 1963 Margareta Heus, Alex B. Novikoff
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