Results 161 to 170 of about 1,703,947 (251)

Co-administration of nobiletin and tetrahydrocurcumin enhanced the cytotoxicity to breast cancer through inhibiting CYP1A1 enzyme: from the perspective of pharmacokinetic interactions. [PDF]

Discov Oncol
Song H, Gao F, Niu Z, Liu X, Wang X, Cao W, Wang H.   +6 more
europepmc   +1 more source

Bioipharmaceutical aspects of FK-506 [PDF]

, 1987
Burckart, GJ, Makowka, L, Sanghvi, AT, Selftman, H, Starzl, TE, Todo, S, Venkataramanan, R, Warty, VS, Zemaitis, MA   +8 more
core  

Species Differences in the Biotransformation of Aflatoxin B1: Primary Determinants of Relative Carcinogenic Potency in Different Animal Species. [PDF]

Toxins (Basel)
Eaton DL, Williams DE, Coulombe RA.
europepmc   +1 more source

Species-specific gene expression manipulation in humanized livers of chimeric mice via siRNA-encapsulated lipid nanoparticle treatment. [PDF]

Mol Ther Methods Clin Dev
Yamazaki K, Kubara K, Sugahara G, Muto H, Yamamoto M, Mano Y, Mitsuhashi K, Yamasaki C, Ishida Y, Tateno C, Suzuki Y.   +10 more
europepmc   +1 more source

Development of a near-infrared fluorescent probe for the selective detection of severe hypoxia. [PDF]

RSC Chem Biol
Kasai T, Fujita K, Komatsu T, Ueno T, Kojima R, Hanaoka K, Urano Y.   +6 more
europepmc   +1 more source

Metabolic Identification Based on Proposed Mass Fragmentation Pathways of the Anabolic Steroid Bolasterone by Gas Chromatography Tandem Mass Spectrometry. [PDF]

Drug Test Anal
Muresan AR, Rahaman KA, Rafique FB, Son J, Kang MJ, Kwon OS.   +5 more
europepmc   +1 more source

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Metabolism of Dietary Flavonoids in Liver Microsomes

Current Drug Metabolism, 2013
Flavonoids undergo substantial hepatic metabolism and the metabolites might significantly contribute to the effects of these dietary constituents. The metabolites of flavonoids in liver can be summarized as follows: 1) For flavones, the hydroxylation appears to occur at the C-4'-, C-3', C-6 and C-8- position when there is a single or no hydroxy group ...
Jianbo Xiao, Petra Högger
openaire   +4 more sources

Metabolism of nitrosoacetoxymethylmethylamine in liver microsomes

Biochemical Pharmacology, 1981
Abstract The carcinogen nitrosoacetoxymethylmethylamine (NAMM)‡ was incubated with mouse liver microsomes. The decomposition rate of NAMM and the formation of methanol were determined. After addition of an NADPH-regenerating system, formaldehyde formation resulting from metabolic degradation of the methyl group of NAMM was measured.
Norbert Frank, Klaus E. Appel, Manfred Wiessler   +2 more
openaire   +3 more sources

Interaction of Cimetidine with Liver Microsomes

Xenobiotica, 1979
1. Ranitidine interacts with liver microsomes from rats pretreated with different inducers of cytochrome P-450 to produce substrate difference optical spectra with a peak at 426-429 nm and a trough at 390-400 nm. 2. Cytochrome P-450 reduced with dithionite in the presence of ranitidine produced substrate difference spectra with a peak at 447 nm. 3.
V. ČSunjić, Slobodan Rendic, R. Toso, Hans-Heinrich Ruf, F. Kajfež   +4 more
openaire   +3 more sources