Results 141 to 150 of about 28,121 (229)

Development and Validation of an LC-MS/MS Method for the Quantitation of JNJ-64619178 (JNJ) in Mouse Plasma: Characterization of In Vitro and In Vivo Pharmacokinetic Properties. [PDF]

Molecules
Ahmed N, Kshirsagar P, Ding L, Murry DJ, Chaturvedi NK, Chhonker YS.   +5 more
europepmc   +1 more source

Combining <i>in vivo</i> and <i>in vitro</i> studies to elucidate the inhibitory effect of resveratrol on vorolanib metabolism. [PDF]

Front Pharmacol
Chen D, Xia H, Cao L, Fu H, Chen Y, Jiang S, Zhan R.   +6 more
europepmc   +1 more source

Genotoxic exposures to volatile organic compounds in golden retrievers with and without multicentric lymphoma. [PDF]

Front Vet Sci
Tindle AN, Krueger LM, Swafford B, Labadie J, Trepanier LA.   +4 more
europepmc   +1 more source

Identification of Reactive Metabolites of Acetaminophen and Saxagliptin in Human Hepatocytes and Hepatic Organoids. [PDF]

Pharmaceutics
Song IS, Pang M, Lee MS, Lee J, Liu KH, Choi MK, Park HJ, Kim H, Lee HS.   +8 more
europepmc   +1 more source

Inhibition of acalabrutinib metabolism by finerenone and its molecular docking studies. [PDF]

Cell Biol Toxicol
Wang P, Fu H, Wu J, Li R, Cao L, Xu RA, Lin W.   +6 more
europepmc   +1 more source

Characterization of the Formation of the Acyl Glucuronide Metabolite of 7-Carboxy-Cannabidiol in Human Liver, Kidney, and Intestinal Microsomes and <i>in Vivo</i> in Mice. [PDF]

ACS Med Chem Lett
Simon KT, Hailemariam SE, Friedman E, Wen YW, Freaney M, Barker-Haliski M, Isoherranen N.   +6 more
europepmc   +1 more source

Use of a cytochrome P450 humanized mouse model to refine schistosomiasis drug discovery. [PDF]

Proc Natl Acad Sci U S A
Davey SD, Forde-Thomas JE, Hulme BJ, Lees K, Costain AH, Evans M, Rinaldi G, Frame L, Stojanovski L, Simeons FRC, Tavendale A, MacLeod AK, Pichon R, Lee YH, Polak O, Chalmers IW, Dankwa B, Odhiambo BK, Guimaraes VH, Hegarty M, Swain MT, Aubrey W, Caldwell N, MacDonald AS, Gilbert IH, Baragaña B, Read KD, Hoffmann KF.   +27 more
europepmc   +1 more source

Optimized UPLC-MS/MS Method for the Simultaneous Quantification of Pazopanib and GSK-1268997 and Its Application to Drug-Drug Interaction Studies. [PDF]

Drug Des Devel Ther
Cao L, Wang P, Li R, Fu H, Wu J, Xia H, Xie S, Zeng C.   +7 more
europepmc   +1 more source

In Vitro Cytochrome P450 Interaction Profile and ADME Characterisation of Gold(I)-Triphenylphosphine Complexes with 6-Alkoxy-9-deazapurine Ligands. [PDF]

Pharmaceutics
Medvedíková M, Vančo J, Trávníček Z, Anzenbacher P.   +3 more
europepmc   +1 more source

Fine-Tuning a Transformer Model for METTL3 Lead Optimization. [PDF]

ACS Bio Med Chem Au
Matter CM, Caflisch A.
europepmc   +1 more source