Results 121 to 130 of about 63,034 (211)

Reaction pattern of alveolar cells in the posttraumatic lung failure [PDF]

, 1987
Jochum, Marianne, Joka, T., Kreutzfelder, E., Oberste-Beulmann, S., Obertacke, U., Pison, V., Redl, H., Schlag, G., Schönfeld, W., Zilow, G.   +9 more
core  

Characterization of trazodone metabolic pathways and species-specific profiles. [PDF]

Front Pharmacol
Petrucci V, Dragone P, Laurenti MC, Oggianu L, Zabela V, Cattaneo A.   +5 more
europepmc   +1 more source

Optimizing the Antibiotic Potency and Metabolic Stability of Pyridomycin Using a Semisynthetic Approach. [PDF]

J Med Chem
Valderrama K, Horlacher O, Publicola G, Eisenring P, Kienle M, Boarbi S, Kiass M, Korduláková J, Chatagnon J, Piveteau C, Leroux F, Savková K, Záhorszká M, Cantrelle FX, Lherbet C, Mourey L, Mikušová K, Mathys V, Aichholz R, Maveyraud L, Altmann KH, Hartkoorn RC.   +21 more
europepmc   +1 more source

Study on Phase I Metabolic Processes and Metabolite Biomarker Identification of Synthetic Cannabinoids 5F-ADB-PINACA and 5F-ADBICA in Human Liver Microsomes and Zebrafish Model. [PDF]

Molecules
Li H, Zheng H, Zhong S, Zhao Y, Lin J, Su H, Qian Z, Wang Y.   +7 more
europepmc   +1 more source

Investigation of the Relevance of CYP3A4 Inhibition on the Pharmacokinetics of the Novel P2X3 Antagonist Filapixant: Results of In Vitro Explorations and a Fixed-Sequence Clinical Trial with Itraconazole in Healthy Volunteers. [PDF]

Int J Mol Sci
Francke K, Rottmann A, Klein S, Höchel J, Friedrich C.   +4 more
europepmc   +1 more source

The Effects of Drugs on CYP3A Enzyme Activity and Protein Expression Through Ubiquitination Modification Regulation. [PDF]

Basic Clin Pharmacol Toxicol
Wang F, Gu X, Hong H, Xia Q, Zhang Y, Song Y, Li B, Fan P.   +7 more
europepmc   +1 more source

Drug-Metabolizing Enzymes in Human Keratinocytes and In Vitro Detection of Cytochrome P450-Mediated Phenolic Lamotrigine Metabolite. [PDF]

Chem Res Toxicol
Deck PN, Müller M, Glässner A, Vogel M, Steffens M, Heubach C, Fechner G, Becker K, Weindl G, Sachs B.   +9 more
europepmc   +1 more source

A Novel Tertiary Carbamate Prodrug Strategy to Overcome Metabolic Barriers in Oral Ketamine Delivery. [PDF]

ChemMedChem
Järvinen J, Adla SK, Tampio J, Jalkanen A, Sloan KB, Huttunen KM, Rautio J.   +6 more
europepmc   +1 more source

NAD(P)⁺-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite. [PDF]

Arch Toxicol
Wu Q, Fang JL, Nagumalli SK, Guo X, Beland FA.   +4 more
europepmc   +1 more source

Extrapolation of in vitro effect concentrations to in vivo bioavailable concentrations using PBK modelling in humans for two classes of persistent and mobile compounds: triazoles and triazines. [PDF]

Arch Toxicol
Ravi Shankar AL, Irwan J, Spaenig M, Carlier M, Hansen T, Zumbülte N, Islam B, Lundquist P, Svensson R, Gouin T, Hamers T, Escher SE.   +11 more
europepmc   +1 more source