Results 101 to 110 of about 2,738,308 (324)
, 2011 Comparative Metabolism of Cinobufagin in Liver Microsomes from Mouse, Rat, Dog, Minipig, Monkey, and HumanCinobufagin (CB), a major bioactive component of the traditional Chinese medicine Chansu, has been reported to have potent antitumor activity.
Ning, Jing +9 more
core +1 more source
Epilepsia, EarlyView.Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer +7 more
wiley +1 more source
Journal of Lipid Research, 1993 Microsomes from liver and several other tissues esterify retinol through both fatty acyl-CoA-dependent and -independent reactions. Two activities, acyl-CoA:retinol acyltransferase (ARAT) and lecithin:retinol acyltransferase (LRAT) activities, have been ...
AC Ross, ES Kempner
doaj +1 more source
In Vitro Metabolic Study of Boc5 in human tissues and Animal Liver Microsomes
, 2009 As the first nonpeptidic agonist of glucagon-like peptide 1 receptor, Boc5 can invoke sustained glycemic control and weight loss in diabetic C57BL/6J mice, and has become a promising hit compound for antidiabetic drug. Boc5 displays good efficiency via i.
梁思成 +4 more
core
Exploration, EarlyView.The deficiency of PNLDC1 exacerbates the advancement of CRC. PNLDC1 interacts with TUBB4B mRNA to regulate the p53–p21–CDK2–cyclin E2 pathway, thereby influencing the G2/M phase of the cell cycle. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related mortality, highlighting the urgent need for novel therapeutic strategies.
Lexin Liu +18 more
wiley +1 more source
Journal of Lipid Research, 1981 Acylcoenzyme A: cholesterol acyltransferase (ACAT) activity was studied in hepatic microsomes of cynomolgus monkeys fed either commercial chow or an atherogenic diet of high cholesterol and saturated fat content.
S N Mathur +3 more
doaj +1 more source
UGT1A6 and UGT1A9 involving in the metabolism of daphnetin by human liver microsomes
, 2009 Daphnetin (7, 8-dihydroxycoumarin), one of coumarin derivatives, is the major bioactive constituent from Daphne odora (Thymelaeaceae). Previous studies indicated that daphnetin has the anti-coagulant activity like other coumarin analogs, and other ...
梁思成 +4 more
core
Clofibric Acid Increases the Formation of Oleic Acid in Endoplasmic Reticulum of the Liver of Rats
Journal of Pharmacological Sciences, 2011 .: The effects of 2-(4-chlorophenoxy)-2-methylpropionic acid (clofibric acid) on the formation of oleic acid (18:1) from stearic acid (18:0) and utilization of the 18:1 formed for phosphatidylcholine (PC) formation in endoplasmic reticulum in the liver ...
Akihiko Hirose +7 more
doaj +1 more source
A Hemochromogen Component of Liver Microsomes [PDF]
Proceedings of the National Academy of Sciences, 1952 C F, Strittmatter, E G, Ball
openaire +2 more sources
Purification and properties of a cholesteryl ester hydrolase from rat liver microsomes
Journal of Lipid Research, 1999 This report describes a purification procedure for a cholesteryl ester hydrolase (CEH) from female rat liver microsomes, and some structural, immunological, kinetic, and regulatory properties of the enzyme that distinguish the microsomal CEH from other ...
Susana Cristóbal +2 more
doaj +1 more source