Results 101 to 110 of about 34,918 (236)

Hidden Behind Ascites: An Atypical Pediatric Presentation of T‐Cell Acute Lymphoblastic Leukemia—A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT This case describes a child with T‐cell acute lymphoblastic leukemia (T‐ALL) presenting atypically with ascites and bilateral pedal edema, initially suggesting autoimmune hepatitis. The diagnosis was established only after flow cytometry of ascitic fluid.
Kainat Shaikh   +5 more
wiley   +1 more source

GGT‐Normal Cholestasis in an Older Child: A Suspected Case of Benign Recurrent Intrahepatic Cholestasis From Syria

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Cholestasis beyond infancy is uncommon and presents a diagnostic challenge. We report an 11‐year‐old girl presenting with severe pruritus followed by jaundice and a cholestatic biochemical profile with normal gamma‐glutamyl transferase levels. Extensive evaluation excluded infectious, autoimmune, metabolic, and obstructive causes. Liver biopsy
Ahmad Hosiian   +6 more
wiley   +1 more source

In Vitro Metabolism of Medroxyprogesterone Acetate with Human Liver Microsome and Comparison with Rat,Minipig Liver Microsmes and Recombinant Human CYP3A4

open access: yes, 2006
Objective: To study the metabolism of medroxyprogesterone acetate (MPA) in human liver microsomes and compare the metabolim profile with rat, minipig liver mcirosomes and recombinant human CYP3A4.
张江伟, 李巍, 刘勇, 杨凌
core  

Unveiling Hepatic Protein Alterations in Neonatal and Infant Biliary Atresia

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1584-1596, June 2026.
Pediatric populations differ from adults in drug elimination capacity. While current scaling methods account for enzyme and transporter maturation, they overlook comorbidities, such as biliary atresia (BA), a liver disease appearing within the first 2–8 weeks of life that can progress to cirrhosis.
Zubida M. Al‐Majdoub   +5 more
wiley   +1 more source

Harnessing Fatty Acid By‐Products for Diabetes Management: Insights From Nutritional and Biological Research

open access: yeseFood, Volume 7, Issue 3, June 2026.
Bioactive fatty acids from agro‐industrial byproducts are highlighted as a promising avenue for managing diabetes in this review, which aims to develop targeted interventions for optimal utilization and therapeutic benefits. ABSTRACT Diabetes mellitus (DM), influenced by multifaceted factors, creates a complex imbalance within the body. Nutrition plays
Youssef Elouafy   +7 more
wiley   +1 more source

Exploring the Nutraceutical Potential of Achillea millefolium L.: Phytochemical Composition, Biological Activities, and Industrial Applications

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Achillea millefolium Linn., commonly known as yarrow, is an extraordinary medicinal plant. A. millefolium has broad therapeutic potential due to its phytochemistry and essential oil composition. It possesses pharmacological properties, including antidiabetic, antioxidant, anti‐inflammatory, liver‐protective, antimicrobial, and gastroprotective effects,
Tooba Majeed   +14 more
wiley   +1 more source

Reproxalap ‐ A Novel Treatment Option for Allergic Conjunctivitis – A Comprehensive Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Allergic conjunctivitis is a prevalent, immune‐mediated hypersensitivity disorder of the ocular surface affecting 10%–20% of the global population. Current therapeutic options, while effective to some extent, are often limited by side effects and inconsistent efficacy.
Sanila Mughal   +7 more
wiley   +1 more source

Epoxidation of aldrin by rainbow trout liver microsomes

open access: yes
Assay conditions and analytical methods established for the study of epoxidation of the insecticides aldrin and heptachlor, by rat liver microsomes have been employed to study the same reaction catalyzed by trout liver microsomes.
Chan, Timothy Ming-wai
core  

Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11

open access: yes, 2009
In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16[alpha]-hydroxylation by Cytochrome P450-2C11.
Morio Yamada   +3 more
core  

Home - About - Disclaimer - Privacy