Results 91 to 100 of about 34,918 (236)
Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales +12 more
wiley +1 more source
Metabolic stability in human liver microsomes.
, 2015 BG-323 was incubated with pooled human liver microsomes. After reaction initiation with NADPH, reactions were sampled at times 0, 10, 30 and 60 minutes. BG-323 concentrations were determined by LC-MS/MS at each time point (n = 1).
Susan M. Keenan (755174) +5 more
core +1 more source
Evaluation of Liver Damage and Herbal Detoxification of Coral Reef Fish Caused by Ammonia Stress
Aquaculture, Fish and Fisheries, Volume 6, Issue 3, June 2026.Slybum marianum can reduce ammonia stress and enhance liver protection in marine fish. ABSTRACT Ammonia nitrogen can cause serious toxicological damage to fish and cause fish death. This study focused on liver damage caused by ammonia nitrogen stress in coral reef fish and used herbal extracts to improve ammonia poisoning and prevent liver tissue ...
Wei‐Ting Sun +3 more
wiley +1 more source
Archiv der Pharmazie, Volume 359, Issue 6, June 2026.Activation of the voltage gated K+ channel KV7.1 leads to hyperpolarization shift of cell membranes. In a thorough SAR study eight positions of the lead compound (R)‐L3 were modified. (R)‐configuration, the indolylmethyl moiety in 3‐position and the 2‐fluorophenyl moiety in 5‐position appeared to be essential for high KV7.1 activation, whereas an OH ...
Florian Roßner +3 more
wiley +1 more source
Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics
Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1708-1720, June 2026.ABSTRACT Cell‐free protein synthesis (CFPS) is a powerful and versatile platform that supports a wide range of applications, from fundamental studies of the genetic code to scalable and rapid protein production. The recently developed Pichia pastoris CFPS combines advantages of both prokaryotic and eukaryotic systems, including a rapid growth rate ...
Rui Wu +4 more
wiley +1 more source
A New Cytochrome in Liver Microsomes
Journal of Biological Chemistry, 1962 T, OMURA, R, SATO
openaire +2 more sources
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Thymomas are rare epithelial tumors of the anterior mediastinum known for their association with autoimmune and paraneoplastic syndromes, most notably myasthenia gravis (MG). Cardiomyopathy is an exceptionally rare paraneoplastic manifestation.
Manish Barman +5 more
wiley +1 more source
Pediatric Wilson Disease in Sudan: A Rare Case, Sudan Conflict and Diagnostic Challenges
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Wilson disease is rarely reported among African children. Wilson disease is due to a mutation in ATP7B on an autosomal recessive pattern, which causes defective copper excretion and copper accumulation in tissues such as liver and brain.
Amjed Abdu Ali Mohammed +8 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Autoimmune hepatitis is a type of chronic hepatitis that is usually progressive, has unknown etiology, and can occur at any age. In the present case, drug‐associated autoimmune hepatitis (DIAIH) was discussed, and DIAIH secondary to isoniazid (INH) was found in two case reports in the literature.
Murat AY, Erhan Bozkurt
wiley +1 more source
The spatial arrangement of esterases in the microsomal membrane [PDF]
, 1975 Gratzl, Manfred +2 more
core +1 more source