Purification and properties of a cholesteryl ester hydrolase from rat liver microsomes
Journal of Lipid Research, 1999 This report describes a purification procedure for a cholesteryl ester hydrolase (CEH) from female rat liver microsomes, and some structural, immunological, kinetic, and regulatory properties of the enzyme that distinguish the microsomal CEH from other ...
Susana Cristóbal +2 more
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Inhibition of rat microsomal lipid peroxidation by the oral administration of D002
Brazilian Journal of Medical and Biological Research, 2000 The effect of D002, a defined mixture of higher primary alcohols purified from bee wax, on in vivo and in vitro lipid peroxidation was studied. The extent of lipid peroxidation was measured on the basis of the levels of thiobarbituric acid reactive ...
Menéndez R. +4 more
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Clofibric Acid Increases the Formation of Oleic Acid in Endoplasmic Reticulum of the Liver of Rats
Journal of Pharmacological Sciences, 2011 .: The effects of 2-(4-chlorophenoxy)-2-methylpropionic acid (clofibric acid) on the formation of oleic acid (18:1) from stearic acid (18:0) and utilization of the 18:1 formed for phosphatidylcholine (PC) formation in endoplasmic reticulum in the liver ...
Akihiko Hirose +7 more
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Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function [PDF]
, 2018 Visual function in vertebrates critically depends on the continuous regeneration of visual pigments in rod and cone photoreceptors. RPE65 is a well-established retinoid isomerase in the pigment epithelium that regenerates rhodopsin during the rod visual ...
Angueyra, Juan M +11 more
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Journal of Lipid Research, 1989 CL 277,082 (I) was found to be a potent inhibitor of acyl CoA:cholesterol acyltransferase (ACAT, EC 2.3.1.26) in microsomes from a variety of tissues with IC50 values of 0.14 microM for intestinal mucosal microsomes, 0.74 microM for liver, and 1.18 ...
E E Largis +3 more
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In vivo and in vitro assessment of mirtazapine pharmacokinetics in cats with liver disease. [PDF]
, 2018 BackgroundLiver disease (LD) prolongs mirtazapine half-life in humans, but it is unknown if this occurs in cats with LD and healthy cats.Hypothesis/objectivesTo determine pharmacokinetics of administered orally mirtazapine in vivo and in vitro (liver ...
Benson, Kellyi K +6 more
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Dependence of microsomal lipid synthesis on added protein
Journal of Lipid Research, 1964 Lipid synthesis by rat liver microsomes from l-α-glycerophosphate-1-C14 in the presence of palmitic acid, ATP, CoA, and Mg2+ came to a standstill after 30 min while enough cofactors were still present to promote further synthesis.
Ruth Tzur, B. Shapiro
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The uptake in vitro of C14-labeled glycine, L-leucine, and L-lysine by different components of guinea pig liver homogenate [PDF]
, 1950 We have reported (1) that L-lysine labeled with C14 can be incorporated into the proteins of guinea pig liver homogenate under two different conditions.
Borsook, Henry +4 more
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Clinical and Translational SciencePedunculoside and rotundic acid, the most abundant components in plants of the genus Ilex L. (Aquifoliaceae), exhibit biological and pharmacological significance in the treatment of cardiovascular diseases.
Liang Wu +8 more
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Triacylglycerol synthesis in rat adipose tissue : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]
, 1983 Adipose tissue consists of two types of cell; the adipocyte and the non-adipocyte {Rodbell, 1964). The adipocyte is unique amongst mammalian cell types in that one class of component {TG) comprises up to 80% of its weight.
Wilson, Russell Douglas
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