Results 81 to 90 of about 34,918 (236)
Food Frontiers, Volume 7, Issue 4, July 2026.ABSTRACT Barberry (Berberis vulgaris) has emerged as a promising functional food candidate for the management of metabolic syndrome due to its diverse bioactive constituents, particularly berberine. This review synthesizes current experimental and clinical evidence regarding its effects on glycemic control, lipid metabolism, blood pressure regulation ...
Fakhar Shahid +5 more
wiley +1 more source
, 2017 Protoberberine alkaloids including berberine, palmatine, jatrorrhizine, coptisine, and epiberberine are major components in many medicinal plants. They have been widely used for the treatment of cancer, inflammation, diabetes, depression, hypertension ...
Ran Zuo +11 more
core +1 more source
Food Frontiers, Volume 7, Issue 4, July 2026.Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman +6 more
wiley +1 more source
Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
Evidence for glucose-6-phosphate transport in rat liver microsomes.
, 2002 The existence of glucose-6-phosphate transport across the liver microsomal membrane is still controversial. In this paper, we show that S3483, a chlorogenic acid derivative known to inhibit glucose-6-phosphatase in intact microsomes, caused the ...
Isabelle Gerin +3 more
core +1 more source
Protein Science, Volume 35, Issue 7, July 2026.Abstract CYP2J2 is a membrane‐bound cytochrome P450 that is expressed in cardiomyocytes, where it is known to metabolize arachidonic acid into cardioprotective epoxyeicosatrienoic acids (EETs). It consists of transmembrane domains embedded in the hydrophobic segments of the cell membrane and surrounded by various lipids.
Rajatabha Das +3 more
wiley +1 more source
Site-specific oxidation of flavanone and flavone by cytochrome P450 2A6 in human liver microsomes
, 2018 The roles of human cytochrome P450 (P450 or CYP) 2A6 in the oxidation of flavanone [(2R)- and (2S)-enantiomers] and flavone were studied in human liver microsomes and recombinant human P450 enzymes.CYP2A6 was highly active in oxidizing flavanone to form ...
Masayuki Komori (1655731) +11 more
core +1 more source
Alimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 103-111, July 2026.In ANA‐positive patients with suspected autoimmune hepatitis (AIH), liver biopsy rarely altered therapeutic management when alanine aminotransferase (ALT) was below 101 U/L and cirrhosis was absent. These findings suggest that biopsy may be safely deferred in this low‐risk group.
David Mehdi Asgher Niazi +8 more
wiley +1 more source
Metabolism of the prodrug DB868 in monkey liver microsomes.
, 2013 HPLC/UV chromatograms (A) and concentration-time profiles (B) of the prodrug DB868, intermediate metabolites, and active compound (DB829) following incubation of DB868 with male vervet monkey liver microsomes were shown. Incubation mixtures (1 mL at pH 7.
Arlene S. Bridges (301008) +15 more
core +1 more source
ChemMedChem, Volume 21, Issue 11, 15 June 2026.In this work, we identified two novel pleiotropic sinapic acid derivatives with excellent anti‐acetylcholinesterase, antioxidant, and anti‐inflammatory properties. Alzheimer's disease, one of the most widespread neurodegenerative disorders, is known for its multifactorial nature that makes it challenging to treat.
Konstantina Sdougkou +2 more
wiley +1 more source