Results 201 to 210 of about 26,828 (241)

Effect of Ginkgo tablets on the pharmacokinetics of metoprolol in rats: liquid chromatography-tandem mass spectrometry-based study. [PDF]

Am J Transl Res
Zhao BY, Zhang J, Zhao KY, Song Y, Shi YJ, Zeng L, Zeng X, Sheng YG, Luo Y.   +8 more
europepmc   +1 more source

The CYP4/20-HETE/GPR75 axis in the progression metabolic dysfunction-associated steatosis liver disease (MASLD) to chronic liver disease. [PDF]

Front Physiol
Hardwick JP, Song BJ, Rote P, Leahy C, Lee YK, Wolf AR, Diegisser D, Garcia V.   +7 more
europepmc   +1 more source

The effects of CYP2B6 inactivators on the metabolism of ciprofol. [PDF]

PLoS One
Lu M, Zhang X, Li W, Li X, Li S, Yin X, Zhang Z.   +6 more
europepmc   +1 more source

The Importance of Murine Models in Determining In Vivo Pharmacokinetics, Safety, and Efficacy in Antimalarial Drug Discovery. [PDF]

Pharmaceuticals (Basel)
Adebayo G, Ayanda OI, Rottmann M, Ajibaye OS, Oduselu G, Mulindwa J, Ajani OO, Aina O, Mäser P, Adebiyi E.   +9 more
europepmc   +1 more source

Triterpenoids from Ganoderma lucidum inhibit cytochrome P450 enzymes interfering with the metabolic process of specific clinical drugs. [PDF]

Front Pharmacol
Li D, Lin Y, Lv X, Wu Y, Han C, Cao P, Zhang G, Leng A, Zhou J, Wang C.   +9 more
europepmc   +1 more source

Amelioration of Alcoholic Hepatic Steatosis in a Rat Model via Consumption of Poly-γ-Glutamic Acid-Enriched Fermented <i>Protaetia brevitarsis</i> Larvae Using <i>Bacillus subtilis</i>. [PDF]

Foods
Sim SY, Cho HD, Lee SB.
europepmc   +1 more source

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Metabolism of nitrosoacetoxymethylmethylamine in liver microsomes

Biochemical Pharmacology, 1981
Abstract The carcinogen nitrosoacetoxymethylmethylamine (NAMM)‡ was incubated with mouse liver microsomes. The decomposition rate of NAMM and the formation of methanol were determined. After addition of an NADPH-regenerating system, formaldehyde formation resulting from metabolic degradation of the methyl group of NAMM was measured.
Norbert Frank, Klaus E. Appel, Manfred Wiessler   +2 more
openaire   +3 more sources

Interaction of Cimetidine with Liver Microsomes

Xenobiotica, 1979
1. Ranitidine interacts with liver microsomes from rats pretreated with different inducers of cytochrome P-450 to produce substrate difference optical spectra with a peak at 426-429 nm and a trough at 390-400 nm. 2. Cytochrome P-450 reduced with dithionite in the presence of ranitidine produced substrate difference spectra with a peak at 447 nm. 3.
V. ČSunjić, Slobodan Rendic, R. Toso, Hans-Heinrich Ruf, F. Kajfež   +4 more
openaire   +3 more sources

Pigments of rat liver microsomes

Archives of Biochemistry and Biophysics, 1958
Abstract The total hemin content of washed rat liver microsomes is 2.15 times the cytochrome b5 content, only a small part being due to bound hemoglobin. The content of flavine is 4 5 that of cytochrome b5. The flavine probably does not contribute to the DPNH reduced difference spectrum.
openaire   +4 more sources

Interaction of ranitidine with liver microsomes

Xenobiotica, 1982
1. Ranitidine interacts with liver microsomes from rats pretreated with different inducers of cytochrome P-450 to produce substrate difference optical spectra with a peak at 426-429 nm and a trough at 390-400 nm. 2. Cytochrome P-450 reduced with dithionite in the presence of ranitidine produced substrate difference spectra with a peak at 447 nm. 3.
S, Rendić, T, Alebić-Kolbah, F, Kajfez, H H, Ruf   +3 more
openaire   +2 more sources