Results 211 to 220 of about 64,891 (274)

Confounding Effect of Hepatic Carboxylesterase 1 (CES1) Variability on Clopidogrel Oxidation. [PDF]

Mol Pharm
Subash S, Singh DK, Khojasteh SC, Murray BP, Zientek MA, Jones RS, Kulkarni P, Smith BJ, Prasad B.   +8 more
europepmc   +1 more source

A new naphthalene-based fluorogenic substrate for cytochrome P450 4A11. [PDF]

Biochem J
Davydov DR, Ponraj K, Davydova N, Singh DK, Prasad B.   +4 more
europepmc   +1 more source

Beyond-Rule-of-Five Compounds Are Not Different: In Vitro-In Vivo Extrapolation of Female CD-1 Mouse Clearance Based on Merck Healthcare KGaA Compound Set. [PDF]

Pharmaceuticals (Basel)
Maurer CK, Fang Z, Duevel HM, Harlfinger S, Petersson C.   +4 more
europepmc   +1 more source

Preclinical evaluation of tridecaptin M: <i>in vitro</i> and <i>in vivo</i> efficacy against colistin-resistant Gram-negative bacterial pathogens and pharmacokinetics. [PDF]

Antimicrob Agents Chemother
Raka V, Jangra M, Kaur P, Dadwal R, Kansal S, Angrup A, Ray P, Nandanwar H.   +7 more
europepmc   +1 more source

Selective Targeting of Kinesin on Lipid Droplets in the Liver Reduces Serum Lipids

Tripathy S, Mahapatra A, Saharan O, Chatterjee H, Sengupta N, Kamat S, Nair S, Mallik R.   +7 more
europepmc   +1 more source

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Microsomal antigens in developing chick liver

Experimental Cell Research, 1965
Abstract Microsomes from embryonic and adult chick liver have been analyzed by homologous antisera. The deoxycholate-soluble fraction of embryonic microsomes contains a group of antigens typical to this fraction, but present only as a trace in the adult-homologous fraction.
V, MUTOLO, V, D AMELIO, E, PIAZZA
openaire   +2 more sources

Hydroperoxide peroxidase activity in liver microsomes

Life Sciences, 1974
Abstract The oxidation of either NADH or NADPH by cumene hydroperoxide in rat liver microsomes is described. The Km′ for the hydroperoxide varied with the pyridine nucleotide utilized (NADPH, Km′ = 0.91 mM; NADH, Km′ = 3.3 mM). Carbon monoxide did not inhibit the peroxidase activity although a variety of other agents which interact with cytochrome ...
W R, Bidlack, P, Hochstein
openaire   +2 more sources

A microsomal endoribonuclease from rat liver

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1980
An endoribonuclease has been purified about 320-fold from the microsomes of rat liver. The enzyme had an apparent molecular weight of 54 000-58 000 and produced oligonucleotides, each consisting of 3-7 nucleotides from poly(A) and poly(U). No mononucleotide was obtained by the enzymatic hydrolysis of poly(A) and poly(U) under standard coditions.
H, Kumagai, K, Igarashi, T, Takayama, K, Watanabe, K, Sugimoto, S, Hirose   +5 more
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Ethylene Formation in Rat Liver Microsomes

Science, 1966
Reduced triphosphopyridine nucleotide and pyrophosphate-dependent peroxidation of lipids in rat liver microsomes were coupled to the generation of ethylene in the presence of cuprous ions. This system suggests a model for the biogenesis of ethylene in cells.
M, Lieberman, P, Hochstein
openaire   +2 more sources