Results 211 to 220 of about 1,677,689 (317)

Computational and Experimental Investigation of Antidiabetic Drugs on Tofacitinib Metabolism: Molecular Docking, in vitro, and in vivo Studies. [PDF]

Drug Des Devel Ther
Zhou J, Zhang Q, Guan J, Peng X, Lu Z, Zhou Q, Mamun AA, Wang S.   +7 more
europepmc   +1 more source

5'-Nucleotidase of Rat Liver Microsomes [PDF]

Journal of Biological Chemistry, 1960
B. Morton Brenner, Harold L. Segal
openaire   +2 more sources

Divergent Genetic Pathways Underlying Convergent Parasitic Behaviours in Blowflies

Molecular Ecology, Volume 34, Issue 11, June 2025.
ABSTRACT Blowfly (Diptera: Calliphoridae) exhibit diverse feeding strategies, with most species developing on decomposing organic matter. However, parasitism has evolved within the family, and some species convergently gained the ability to explore the tissues of living vertebrate hosts, which imposes critical veterinary, medical, and agricultural ...
Gisele Antoniazzi Cardoso, Pedro Mariano‐Martins, Gustavo Amaral Faria, Inoka Karunaratne, Patricia Jacqueline Thyssen, Tatiana Teixeira Torres   +5 more
wiley   +1 more source

Preclinical pharmacokinetics and in vitro ADME properties of PAT-1102: a novel HDAC inhibitor for cancer therapy. [PDF]

J Cancer Res Clin Oncol
Doreswamy CM, Seekallu S, Venkataramaiah SB, Umesh MC, Devi CS.   +4 more
europepmc   +1 more source

Implications for soluble iron accumulation, oxidative stress, and glial glutamate release in motor neuron death associated with sporadic amyotrophic lateral sclerosis

Neuropathology, Volume 45, Issue 3, Page 177-201, June 2025.
Oxidative stress in sporadic amyotrophic lateral sclerosis (ALS) has been evidenced by accumulation of oxidatively modified products of nucleic acids, lipids, sugars, and proteins in the motor neuron system of brains and spinal cords obtained at autopsy from the patients.
Noriyuki Shibata, Ikuko Kataoka, Yukinori Okamura, Kumiko Murakami, Yoichiro Kato, Tomoko Yamamoto, Kenta Masui   +6 more
wiley   +1 more source

Development of a near-infrared fluorescent probe for the selective detection of severe hypoxia. [PDF]

RSC Chem Biol
Kasai T, Fujita K, Komatsu T, Ueno T, Kojima R, Hanaoka K, Urano Y.   +6 more
europepmc   +1 more source

A preliminary exploration of liver microsomes and PBPK to uncover the impact of CYP3A4/5 and CYP2C19 on tacrolimus and voriconazole drug-drug interactions. [PDF]

Sci Rep
Zhao YC, Zhang YK, Gao W, Liu HY, Xiao CL, Hou JJ, Li JK, Zhang BK, Xiang DX, Sandaradura I, Yan M.   +10 more
europepmc   +1 more source

Typical and atypical metabolic characteristics of three iridaceae isoflavone components: in vitro and in silico studies. [PDF]

Front Pharmacol
Gu J, Zhang H, Wang M, Zhou Y, Deng Z, Shi R.   +5 more
europepmc   +1 more source

Prediction of SPT-07A Pharmacokinetics in Rats, Dogs, and Humans Using a Physiologically-Based Pharmacokinetic Model and In Vitro Data. [PDF]

Pharmaceutics
Zhu X, Kong W, Wang Z, Liu X, Liu L.
europepmc   +1 more source

The In Vitro Pharmacokinetics of Medicinal Plants: A Review. [PDF]

Pharmaceuticals (Basel)
Chaves de Jesus P, Rego Rodrigues Silva DM, Macedo Moura PH, Gopalsamy RG, Dias Silva EE, Dos Santos Barreto M, Santana Santos R, Santos Martins AY, de Freitas Almeida AG, Santana Corrêa AK, Alves da Mota Santana L, Hariharan G, Gibara Guimarães A, Pinto Borges L.   +13 more
europepmc   +1 more source