Results 121 to 130 of about 35,679 (167)

A Novel Tertiary Carbamate Prodrug Strategy to Overcome Metabolic Barriers in Oral Ketamine Delivery. [PDF]

ChemMedChem
Järvinen J, Adla SK, Tampio J, Jalkanen A, Sloan KB, Huttunen KM, Rautio J.   +6 more
europepmc   +1 more source

Pharmacokinetics, pathology and efficacy of SARS-CoV-2 main protease inhibitor VPC285785 in a murine model of coronavirus infection. [PDF]

Sci Rep
Smith JR, Toro A, Sabater A, Kovacic S, Ban F, Arevalo AP, Crispo M, Gueron G, Young RN, Cherkasov A.   +9 more
europepmc   +1 more source

Simvastatin inhibits 20-Hydroxyeicosatetraenoic acid formation: docking and in vitro assay. [PDF]

BMC Pharmacol Toxicol
Jarrar Y, Almansour M, Ahmad MA, Al-Najjar BO, Al-Doaiss AA, Shilbayeh SAR, Lee SJ.   +6 more
europepmc   +1 more source

Phenolic Derivatives of <i>Astragalus aitosensis</i> with Selective MAO-B Inhibition and Mitochondrial Protection. [PDF]

Molecules
Enchev P, Kondeva-Burdina M, Mateev E, Ionkova I, Zarev Y.   +4 more
europepmc   +1 more source

Evaluation the inhibitory effect of nicardipine on the metabolism of quetiapine. [PDF]

Front Pharmacol
Yang J, Xia H, Li Q, Li R, Cao L, Tang C.   +5 more
europepmc   +1 more source

Simvastatin Improves the High-Fat-Diet-Induced Metabolic Disorder in Juvenile Chinese Giant Salamander (<i>Andrias davidianus</i>) Through Inhibiting Endoplasmic Reticulum Stress and Enhancing Mitochondrial Function. [PDF]

Animals (Basel)
Wang Y, Chen J, Dong Y, Du J, Ma S, Wang H, Wang Y, Li X.   +7 more
europepmc   +1 more source

Bioactive flavonoids from Anacardium occidentale as promising natural inhibitors of Cryptococcus neoformans: a computational perspective on secondary metabolites against critical fungal pathogens. [PDF]

Arch Microbiol
da Silva MVF, Silva J, de Oliveira VM, da Rocha MN, de Morais SM, Marinho ES.   +5 more
europepmc   +1 more source

Use of a cytochrome P450 humanised mouse model to refine schistosomiasis drug discovery

Davey SD, Forde-Thomas JE, Hulme BJ, Lees K, Costain AH, Evans M, Rinaldi G, Frame L, Stojanovski L, Simeons FRC, Tavendale A, Kenneth MacLeod A, Pichon R, Lee Y, Polak O, Chalmers IW, Dankwa B, Odhiambo BK, Guimaraes VH, Hegarty M, Swain MT, Aubrey W, Caldwell N, MacDonald AS, Gilbert IH, Baragaña B, Read KD, Hoffmann KF.   +27 more
europepmc   +1 more source

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Microsomal Proteomics

2009
Proteomic profiling of subcellular compartments has many advantages over traditional proteomic approaches using whole cell lysates as it allows for detailed proteome analysis of a specific organelle and corresponding functional characteristics. The microsome is a critical, membranous compartment involved in the synthesis, sorting, and secretion of ...
Diana M, Wong, Khosrow, Adeli
openaire   +2 more sources