Results 121 to 130 of about 97,218 (302)
Studies on biosynthesis of cholesterol. 8. The effect of Mg2+ and Mn2+ ions and of adenosine triphosphate on enzymic activity of microsomes in sterol biosynthesis from mevalonic acid [PDF]
, 1959 Luc E. Gosselin, G. Popják
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Andrology, EarlyView.Abstract Objectives This study aimed to evaluate the pharmacodynamic effects of administering tunodafil hydrochloride with alcohol on blood pressure and heart rate in healthy Chinese males, and to investigate the mutual pharmacokinetic interactions and safety of the combination.
Dingyuan Hu +18 more
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Some chemical components of mitochondria and microsomes from germinating castor beans [PDF]
, 1957 Takashi Akazawa, Harry Beevers
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Opportunities of patient‐derived organoids in drug development
British Journal of Pharmacology, EarlyView.Various model systems are utilised during drug development starting from basic research, moving to preclinical research and development for clinical applications in order to identify new drugs to improve human health. However, there are characteristics of humans that are not captured by established models.
Antonia Büning, Elena Reckzeh
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The Oxidation of TPNH by Rat Liver Microsomes and its Stimulation by Inducing Agents. [PDF]
, 1959 Alexandra von der Decken +3 more
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Coloration Technology, EarlyView.Abstract Anthraquinone dyes are known for their significant colour (brightness of shade in the red, blue and green areas) and light fastness properties compared with other synthetic dyes (such as azo‐based dyes). However, challenging multi‐step synthesis of anthraquinones and limited access to fewer substituents result in insufficient reactivity ...
Arvind Negi +2 more
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Cell Proliferation, EarlyView.Intracellular tryptophan levels modulate selective autophagy of FTH1 via the NCOA4 pathway. This autophagic process then inhibits 6‐HMT synthesis, which then results in an increase in reactive oxygen species and ferroptosis. ABSTRACT Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options.
Xinxiang Cheng +10 more
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The photochemical action spectrum of the carbon monoxide inhibited hydroxylation of cyclohexane by rat liver microsomes [PDF]
, 1969 H. Diehl, S Căpâlnă, V. Ullrich
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Autophagy in PE: Dispute, Role and Potential Target
Cell Proliferation, EarlyView.Autophagy homeostasis serves as a central hub regulating vascular remodelling during pregnancy. It integrates maternal, genetic, and fetal factors; shapes the functions of immune cells (NK cells, macrophages, and T cells); restrains endothelial inflammatory responses (cytokines, endothelial cell, oxidative/ER stress, and protein aggregation); and ...
Miao Xu +12 more
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Enzymic formation of oestrone 3-glucuronide by rabbit-liver microsomes [PDF]
, 1963 Smith Er, H. Breuer
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