Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11 [PDF]
In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16[alpha]-hydroxylation by Cytochrome P450-2C11.
Eiichi Akaho+3 more
core +1 more source
Some chemical components of mitochondria and microsomes from germinating castor beans [PDF]
Takashi Akazawa, Harry Beevers
openalex +1 more source
Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta+8 more
wiley +1 more source
Δ6- and Δ5-desaturase activities in the human fetal liver: kinetic aspects
Δ6- and Δ5-desaturase activities were studied in human fetal liver microsomes obtained after legally approved therapeutic abortion. Enzyme activities were measured by a radiochemical method using reverse-phase high performance liquid chromatography (HPLC)
Annie Rodriguez+5 more
doaj
Transformers for molecular property prediction: Domain adaptation efficiently improves performance [PDF]
Most of the current transformer-based chemical language models are pre-trained on millions to billions of molecules. However, the improvement from such scaling in dataset size is not confidently linked to improved molecular property prediction. The aim of this study is to investigate and overcome some of the limitations of transformer models in ...
arxiv
The Oxidation of TPNH by Rat Liver Microsomes and its Stimulation by Inducing Agents. [PDF]
Alexandra von der Decken+3 more
openalex +1 more source
The oxidative desaturation of [1-14C]eicosa-8,11-dienoic acid to eicosa-5,8,11-trienoic acid by rat liver microsomes was studied, and the kinetic conditions appropriate to measure the specific activity of the enzyme were determined.
Juan C. Castuma+2 more
doaj
Changes in the chemical composition and the enzymic activities of hepatic microsomes of the chick embryo during development [PDF]
JK Pollak, DB Ward
openalex +1 more source
Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke+2 more
wiley +1 more source
Export of honeybee prepromelittin in Escherichia coli depends on the membrane potential but does not depend on proteins secA and secY [PDF]
Honeybee prepromelittin (70 amino acid residues), the precursor of an eukaryotic secretory protein, and a hybrid protein between prepromelittin and mouse dihydrofolate reductase (257 amino acid residues) were expressed in Escherichia coli and ...
Cobet, Werner W. E.+3 more
core