Cross-Species Multitask Learning with Molecular and ADME Descriptors for Liver Microsomal Metabolic Stability. [PDF]
Comput Struct Biotechnol JSeomun S, Yoo S.
europepmc +1 more source
Rat brain microsomes: aggregation and fusion of reconstituted vesicles
, 1989 (A) Liposomes are prepared from rat brain microsomallipid and loaded with either Tb3+ or dipicolinic acid (OPA) to test fusion with the Tb/DPA method. (B) The addition of either Ca2+ or Mg2+ to loaded liposomes produces fluorescence, which is due to ...
ARIENTI, Giuseppe, CORAZZI, Lanfranco
core
The Role of Oxidative Stress in Periodontitis
Journal of Periodontal Research, EarlyView.Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
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Comparative metabolism of Benzydamine in domestic animals
, 1998 Benzydamine is an antiinflammatiry drug used both in humans and animals. In man and in laboratory species it is largerly metabolized and two main unconiugated derivatives are described.
ZAGHINI A. +4 more
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Cuticular Waxes in Altered Environments and Their Role in Leaf Water Loss Dynamics
Plant, Cell &Environment, EarlyView.ABSTRACT Cuticular waxes undeniably form the primary barrier restricting uncontrolled water loss from leaves, yet the functional consequences of environmentally induced wax modifications for residual (cuticular) transpiration remain a matter of debate. This review summarises current knowledge on how major abiotic stimuli influence foliar cuticular wax ...
Lena Herzig +2 more
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Modular assembly and property profiling of an expansive, shape-defined library of pentacyclic saturated N-heterocycles. [PDF]
Chem SciBoschi E +12 more
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The spatial arrangement of esterases in the microsomal membrane [PDF]
, 1975 Gratzl, Manfred +2 more
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Physiological and anatomical determinants of placental drug transfer
The Journal of Physiology, EarlyView.Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis +3 more
wiley +1 more source
Cytochrome P450-Mediated Metabolism of Antimycobacterial <i>N</i>α-Aroyl-<i>N</i>-aryl-phenylalanine Amides. [PDF]
ACS Infect DisDoering J +13 more
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