Results 211 to 220 of about 129,619 (377)

Prediction of SPT-07A Pharmacokinetics in Rats, Dogs, and Humans Using a Physiologically-Based Pharmacokinetic Model and In Vitro Data. [PDF]

Pharmaceutics
Zhu X, Kong W, Wang Z, Liu X, Liu L.
europepmc   +1 more source

METABOLISM OF DRUGS IN OLD RATS (I) ACTIVITIES OF NADPH-LINKED ELECTRON TRANSPORT AND DRUG-METABOLIZING ENZYME SYSTEMS IN LIVER MICROSOMES OF OLD RATS

, 1968
Ryuichi Kato, Akira Takanaka
openalex   +1 more source

Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of <i>Mycobacterium tuberculosis</i>. [PDF]

ACS Infect Dis
Green SR, Harrison JR, Thompson S, Murugesan D, Libardo MDJ, Engelhart CA, Meshanni J, Fletcher D, Scullion P, Edwards D, Epemolu O, Mutter N, Shishikura Y, Riley J, Ioerger TR, Roca Guillén JJ, López LG, Read KD, Barry CE, Schnappinger D, Wyatt PG, Boshoff HIM, Cleghorn LAT.   +22 more
europepmc   +1 more source

Purification and Properties of an Enzyme in Human Blood and Rat Liver Microsomes Catalyzing the Formation and Hydrolysis of γ-Lactones

, 1966
William N. Fishbein, Samuel P. Bessman
openalex   +1 more source

Genotoxic Herbicide Exposures in Golden Retrievers With and Without Multicentric Lymphoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Canine multicentric lymphoma (CML) is one of the most common malignancies in dogs. Although breed risk is important, environmental factors such as herbicides have also been implicated. The objective of this study was to determine whether genotoxic exposures to the herbicides 2,4‐D and glyphosate are associated with CML, using dogs from the ...
Ashleigh N. Tindle, Lauren M. Krueger, Brenna Swafford, Erin Mani, Camille Danielson, Julia Labadie, Lauren A. Trepanier   +6 more
wiley   +1 more source

A preliminary exploration of liver microsomes and PBPK to uncover the impact of CYP3A4/5 and CYP2C19 on tacrolimus and voriconazole drug-drug interactions. [PDF]

Sci Rep
Zhao YC, Zhang YK, Gao W, Liu HY, Xiao CL, Hou JJ, Li JK, Zhang BK, Xiang DX, Sandaradura I, Yan M.   +10 more
europepmc   +1 more source

Import of Small Secretory and Membrane Proteins into the Endoplasmic Reticulum [PDF]

, 1988
Kamp, Jos A. F. op den, Kaßeckert, Brigitta, Müller, Günter, Sagstetter, Maria, Schlenstedt, Gabriel, Wiech, Hans, Zimmermann, Richard   +6 more
core  

Activation of Protein Synthesis by Microsomes from Aging Beet Disks

, 1967
R. John Ellis, I. R. MACDONALD
openalex   +2 more sources

A Rapid and Sensitive Method for the Measurement of Biological Oxidation of an Aromatic Hydrocarbon Catalyzed by Liver Microsomes. [PDF]

, 1967
Robert Nilsson, Gunnar Ahnström, Tore Ledaal, Pär Holmberg, G. Eriksson, R. Blinc, S. Paušak, L. Ehrenberg, J. Dumanović   +8 more
openalex   +1 more source

The ins and outs of liver fat metabolism: The effect of phenotype and diet on risk of intrahepatic triglyceride accumulation

Experimental Physiology, EarlyView.
Abstract In health, the liver is a metabolically flexible organ that plays a key role in regulating systemic lipid and glucose concentrations. There is a constant flux of fatty acids (FAs) to the liver from multiple sources, including adipose tissue, dietary, endogenously synthesized from non‐lipid precursors, intrahepatic lipid droplets and recycling ...
Kieran Smith, Kaitlyn M. J. H. Dennis, Leanne Hodson   +2 more
wiley   +1 more source