Results 111 to 120 of about 359,607 (329)
The mechanism of anaphase spindle elongation: uncoupling of tubulin incorporation and microtubule sliding during in vitro spindle reactivation. [PDF]
, 1988 To study tubulin polymerization and microtubule sliding during spindle elongation in vitro, we developed a method of uncoupling the two processes. When isolated diatom spindles were incubated with biotinylated tubulin (biot-tb) without ATP, biot-tb was ...
CANDE, W. Zacheus +2 more
core
Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain
Advanced Materials, EarlyView.A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng +11 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.Thermal annealing improves the structure, stiffness, and piezoelectric properties of poly(vinylidene flouride‐trifluoroethylene) (PVDF‐TrFE) nanofiber scaffolds. These annealed scaffolds promote Schwann cell proliferation and matrix remodeling in vitro and demonstrate in vivo biocompatibility.
Maksym Krutko +12 more
wiley +1 more source
The α-Tubulin gene TUBA1A in Brain Development: A Key Ingredient in the Neuronal Isotype Blend
Journal of Developmental Biology, 2017 Microtubules are dynamic cytoskeletal polymers that mediate numerous, essential functions such as axon and dendrite growth and neuron migration throughout brain development.
Jayne Aiken +3 more
doaj +1 more source
Advanced Therapeutics, EarlyView.This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen +2 more
wiley +1 more source
Advanced Theory and Simulations, EarlyView.This study presents a robust 3D simulation for BBMC, focusing on both fixed and receding receiver scenarios across various conditions. Key parameters such as D, Q, u, and d are tested at different values to assess the performance and reliability of BBMC in applications like drug delivery, addressing critical challenges in nanoscale communication with ...
Mustafa Ozan Duman +3 more
wiley +1 more source
Neural Regeneration Research, 2015 The transplantation of polylactic glycolic acid conduits combining bone marrow mesenchymal stem cells and extracellular matrix gel for the repair of sciatic nerve injury is effective in some respects, but few data comparing the biomechanical factors ...
Yang Wang +4 more
doaj +1 more source
Microtubule Organization and Microtubule-Associated Proteins (MAPs)
, 2016 Dendrites have a unique microtubule organization. In vertebrates, dendriticmicrotubules are organized in antiparallel bundles, oriented with their plusends either pointing away or toward the soma. The mixed microtubule arrayscontrol intracellular trafficking and local signaling pathways, and are essential fordendrite development and function.
Tortosa Binacua, E. +2 more
openaire +3 more sources
Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation
Advanced Science, EarlyView.At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao +14 more
wiley +1 more source