Results 241 to 250 of about 453,492 (382)

Energy Deficiency‐Induced ATG4B Nuclear Translocation Inhibits PRMT1‐Mediated DNA Repair and Promotes Leukemia Progression

Advanced Science, EarlyView.
This study demonstrated that ATG4B translocates from the cytoplasm to the nucleus during energy deficiency. Nuclear ATG4B inhibits DNA repair by interacting with PRMT1. The nuclear ATG4B‐mediated DNA repair defect is significantly exacerbated within acute myeloid leukemia (AML) cells, promoting leukemia progression in an AML mouse model.
Zhenkun Wang, Xianli Zhang, Yuanyuan Zhou, Shuyi Lin, Yuting Fu, Haiping Liu, Qiongdan Gao, YanHong Xiao, Zhao Yin, Shuang Liu, Kexiu Huang, Suqi Deng, Juan Du, Hui Zeng, Jia Wang, Jinping Zheng, Qinghua Zhou, Tianfeng Chen, Xiaoling Gao, Zhenyu Ju, Bo Liu   +20 more
wiley   +1 more source

Active spiralling of microtubules driven by kinesin motors. [PDF]

Sci Rep
Ng'ang'a DK, Kang'iri SM, Hess H, Nitta T.   +3 more
europepmc   +1 more source

Emerging cGAS‐STING Agonist‐Based Nanotherapeutics: Mechanistic Insights and Applications in Cancer Combination Therapy

Advanced Science, EarlyView.
This review summarizes recent advances in cGAS‐STING agonist‐based nanotherapeutics for cancer combination therapy. It explores nanoparticle‐mediated delivery strategies, underlying molecular mechanisms, and combinatorial applications with chemotherapy, radiotherapy, targeted therapy, phototherapy, sonodynamic therapy, and immunotherapy.
Zhaomeng Wang, Yongjun Wang, Zhonggui He, Caigang Liu   +3 more
wiley   +1 more source

Comparison of the Microtubule Proteins of Neuroblastoma Cells, Brain, and Chlamydomonas Flagella

, 1971
J.B. Olmsted, George B. Witman, Kathryn E. Carlson, Joel L. Rosenbaum   +3 more
openalex   +1 more source

THE MECHANISM OF SOMATIC ASSOCIATION IN COMMON WHEAT, TRITICUM AESTIVUM L. III. DIFFERENTIAL AFFINITY FOR NUCLEOTIDES OF SPINDLE MICROTUBULES OF PLANTS HAVING DIFFERENT DOSES OF THE SOMATIC-ASSOCIATION SUPPRESSOR [PDF]

, 1970
Lydia Avivi, Moshe Feldman, W. Bushuk
openalex   +1 more source

Open Challenges and Opportunities in Piezoelectricity for Tissue Regeneration

Advanced Science, EarlyView.
This review provides an intriguing review of the recent advancements, challenges, and future perspectives regarding the application of piezoelectric scaffolds in tissue regeneration. The detailed exposition is anticipated to propel the advancement of personalized and intelligent piezoelectric implants, thereby fostering significant progress in this ...
Xiaoling Deng, Yu Zhuang, Jinjie Cui, Liyun Wang, Huilu Zhan, Xudong Wang, Kaili Lin, Changyong Yuan   +7 more
wiley   +1 more source

Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats. [PDF]

Bone Joint Res
Yang JJ, Xu SW, Zhang XY, Mao WF, Wu YF.
europepmc   +1 more source

Multicellular rosette formation during cell ingression in the avian primitive streak [PDF]

, 2007
Akiyama, Bertocchini, Blankenship, Chapman, Chuai, Ciruna, Cui, Etienne-Manneville, Graeper, Gundersen, Hamburger, Kelly, Kroboth, Lansbergen, Lawson, Mikawa, Mimori-Kiyosue, Mogensen, Mogenson, Stern, Sun, Vakaet, Watanabe, Watanabe, Wittmann, Yang   +25 more
core   +1 more source

Enhanced Single‐Particle Upconversion Imaging via Energy Migration Boosting

Advanced Science, EarlyView.
A core‐shell‐shell Yb3⁺/Er3⁺ UCNP architecture is engineered to balance energy migration and back energy transfer, yielding more than a tenfold enhancement in single‐particle brightness. Leveraging these optimized probes, it achieves long‐term, high‐resolution single‐particle tracking in live neurons, uncovering coordinated transport mechanisms of ...
Yanxin Zhang, Rongrong Wen, Tianli Zhai, Wenrui Zhang, Fan Ding, Huan Ling, Yunxiang Zhang, Qian Liu   +7 more
wiley   +1 more source

Microtubule networks in zebrafish hair cells facilitate presynapse transport and fusion during development. [PDF]

Elife
Hussain S, Pinter K, Uhl M, Wong HT, Kindt KS.   +4 more
europepmc   +1 more source