Results 241 to 250 of about 199,967 (323)

Induction and Manipulation of Biomolecular Condensates Through Spatially Heterogeneous Solution Conditions

ChemBioChem, EarlyView.
In this concept article, it is discussed how spatial control over the formation and movement of biomolecular condensates (BMCs) can be achieved and how this type of control can help in the reliable generation and study of BMCs. Spatial control over BMCs is crucial in vivo and therefore also desirable for in vitro studies in order to approach relevant ...
Alexander K. Buell
wiley   +1 more source

Repeated Exposure to Sevoflurane in Neonatal Mice Induces Cognitive and Synaptic Impairments in a TTLL6-Mediated Tubulin Polyglutamylation Manner. [PDF]

CNS Neurosci Ther
Yu Y, Zhao Y, Feng J, Lian N, Yu J, Yang Y, Yao J, Yu Y.   +7 more
europepmc   +1 more source

Comparison of the Microtubule Proteins of Neuroblastoma Cells, Brain, and Chlamydomonas Flagella

, 1971
J.B. Olmsted, George B. Witman, Kathryn E. Carlson, Joel L. Rosenbaum   +3 more
openalex   +1 more source

An Indole Dearomatization Strategy for the Synthesis of Pseudo‐Natural Products

ChemBioChem, Accepted Article.
The indole moiety is a privileged fragment that frequently populates existing bioactive compound collections. We describe the development of an indole‐dearomatization sequence and its application for library expansion of a collection of indole‐containing pseudo‐NPs.
Joseph G.F. Hoock, Annina Burhop, Luca C. Greiner, Beate Schölermann, Celine Da Cruz Lopes Guita, Jie Liu, Sukdev Bag, Axel Pahl, Sonja Sievers, Rebecca Scheel, Carsten Strohmann, Slava Ziegler, Michael Grigalunas, Herbert Waldmann   +13 more
wiley   +1 more source

Downregulation of EB1 impedes Cx43 localization and cardiac conduction after hypothermic ischemia-reperfusion in rats. [PDF]

PeerJ
Wen C, Yang R, Yi J, Cao Y, Song Y, An L, Wang Z, Gao H.   +7 more
europepmc   +1 more source

A Proteomics Profiling Reveals the Neuroprotective Effects of Melatonin on Exogenous β‐amyloid‐42 Induced Mitochondrial Impairment, Intracellular β‐amyloid Accumulation and Tau Hyperphosphorylation in Human SH‐SY5Y Cells

Cell Biology International, EarlyView.
ABSTRACT Alzheimer's disease (AD) is prevalent in the elderly population and characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), composed of tau proteins, and extracellular deposition of beta‐amyloid protein (Aβ). The present study aimed to investigate the neuroprotective effects of melatonin on Aβ42‐induced AD‐like ...
Jiraporn Panmanee, Matthew Phanchana, Phorutai Pearngam, Nopphon Petchyam, Kornkanok Promthep, Ponlawit Wisomka, Suchanoot Kutpruek, Supitcha Pannengpetch, Tanya Prasertporn, Sujira Mukda, Piyarat Govitrapong, Chutikorn Nopparat   +11 more
wiley   +1 more source

Elucidating the interactions between Kinesin-5/BimC and the microtubule: insights from TIRF microscopy and molecular dynamics simulations. [PDF]

Brief Bioinform
Guo W, Gao Y, Du D, Sanchez JE, Li Y, Qiu W, Li L.   +6 more
europepmc   +1 more source

Acetylation‐Deacetylation‐Driven Natural Product Biosynthesis

ChemistryEurope, EarlyView.
This review summarizes the role of acetylation‐deacetylation in natural product biosynthesis, including acetylation followed by deacetylation after several biosynthetic steps, acetylation‐mediated rearrangement, acetylation‐triggered elimination, and the acetylation cycle as a regulatory mechanism. These processes are vital for the formation of complex
Huibin Wang, Ikuro Abe
wiley   +1 more source

NuMA is a mitotic adaptor protein that activates dynein and connects it to microtubule minus ends. [PDF]

J Cell Biol
Colombo S, Michel C, Speroni S, Ruhnow F, Gili M, Brito C, Surrey T.   +6 more
europepmc   +1 more source

In Vitro Aggregation of Cytoplasmic Microtubule Subunits

, 1972
Gary G. Borisy, J.B. Olmsted, R. A. Klugman   +2 more
openalex   +1 more source