Results 241 to 250 of about 407,687 (331)

Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2. [PDF]

Elife
Chen S, Basiashvili T, Hutchings J, Sanz Murillo M, Villagran Suarez A, Xiong E, Alegrio Louro J, Leschziner AE, Villa E.   +8 more
europepmc   +1 more source

Microtubules.

Cell structure and function, 1977
openaire   +2 more sources

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

Advanced Science, EarlyView.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside, Angela Jacobi, Shivakumar Keerthikumar, Vaibhav Mahajan, Michelle Richards, Birunthi Niranjan, Linda Teng, Nicholas Choo, Johannes Low Jun Wei, Gail P Risbridger, Mitchell G Lawrence, Anna V. Taubenberger   +11 more
wiley   +1 more source

A Statistical Mechanics Model to Decode Tissue Crosstalk During Graft Formation

Advanced Science, EarlyView.
We introduce a statistical mechanics framework to decode the genomic crosstalk governing plant grafting. By integrating evolutionary game theory with transcriptomics, we reconstruct idopNetworks (informative, dynamic, omnidirectional, and personalized networks) that map scion–rootstock interactions.
Ang Dong, Yihan Meng, Stephen Shing‐Toung Yau, Shing‐Tung Yau, Rongling Wu   +4 more
wiley   +1 more source

Elevated SUN1 promotes migratory cell polarity defects through mechanically coupling microtubules to the nuclear lamina. [PDF]

Commun Biol
Li Y, Zhang Y, Chen M, Antoku S, Ding J, Huang K, Gundersen GG, Chang W.   +7 more
europepmc   +1 more source

Machine Learning‐Based Estimation of Experimental Artifacts and Image Quality in Fluorescence Microscopy

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The use of image quality metrics in combination with machine learning enables automatic image quality assessment for fluorescence microscopy images. The method can be integrated into the experimental pipeline for optical microscopy and utilized to classify artifacts in experimental images and to build quality rankings with a reference‐free approach ...
Elena Corbetta, Thomas Bocklitz
wiley   +1 more source

Peptide-based strategies for overcoming taxol-resistance in cancer therapy - a narrative review. [PDF]

Pharmacol Rep
Długosz-Pokorska A, Gach-Janczak K.
europepmc   +1 more source

SuperResNET: Model‐Free Single‐Molecule Network Analysis Software Achieves Molecular Resolution of Nup96

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
SuperResNET is a powerful integrated software that reconstructs network architecture and molecular distribution of subcellular structures from single molecule localization microscopy datasets. SuperResNET segments the nuclear pore complex and corners, extracts size, shape, and network features of all segmented nuclear pores and uses modularity analysis
Yahongyang Lydia Li, Ismail M. Khater, Christian Hallgrimson, Ben Cardoen, Timothy H. Wong, Ghassan Hamarneh, Ivan R. Nabi   +6 more
wiley   +1 more source

Effects of microtubule (de)tyrosination on the morphology and motility of Trypanosoma brucei and cross-talk with polyglutamylation. [PDF]

Biol Open
Thein M, Wunderlich H, Brehm L, Wagner S, Weiss M, Ersfeld K.   +5 more
europepmc   +1 more source

1SB05 Observation of conformational changes of kinesin walking along microtubules using single molecule FRET technique

, 2004
富重 道雄
openalex   +2 more sources