Results 291 to 300 of about 199,967 (323)

In vitro reconstitution of minimal human centrosomes

open access: yes
Rios MU   +5 more
europepmc   +1 more source

Microtubules and microtubule-associated proteins [PDF]

open access: possibleCurrent Opinion in Cell Biology, 1995
Microtubule research is becoming increasingly diverse, reflecting the many isoforms and modifications of tubulin and the many proteins with which microtubules interact. Recent advances are particularly visible in four areas: microtubule motor proteins (their structures, stepping modes, and forces); microtubule nucleation (the roles of centrosomes and ...
Mandelkow, Eckhard, Mandelkow, Eva
openaire   +3 more sources
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Microtubule-Associated Proteins and the Flexibility of Microtubules

Biochemistry, 1995
Experiments were conducted to learn whether the binding of microtubule-associated proteins (MAPs) to microtubules alters the flexibility of the microtubules. Flexibility was measured in vitro by two established techniques. The first employed measurement of the bending of the microtubule in a flow of buffer; the second involved repeated measurement of ...
Robley C. Williams, Jeffrey C. Kurz
openaire   +3 more sources

Microtubule self-repair

Current Opinion in Cell Biology, 2021
The stochastic switching between microtubule growth and shrinkage is a fascinating and unique process in the regulation of the cytoskeleton. To understand it, almost all attention has been focused on the microtubule ends. However, recent research has revived the idea that tubulin dimers can also be exchanged in protofilaments along the microtubule ...
Manuel Théry   +3 more
openaire   +4 more sources

Isolation of Microtubules and Microtubule-Associated Proteins

2016
Microtubules are essential cellular structures in plant cells. They are polymerized from tubulin dimers and are regulated by microtubule-associated proteins (MAPs). Here, we describe a protocol for purifying tubulin dimers and MAPs from plant cells.
Seiji Sonobe, Takahiro Hamada
openaire   +3 more sources

Microtubules and Microtubule Motors: Mechanisms of Regulation

1996
Microtubule-based motility is precisely regulated, and the targets of regulation may be the motor proteins, the microtubules, or both components of this intricately controlled system. Regulation of microtubule behavior can be mediated by cell cycle-dependent changes in centrosomal microtubule nucleating ability and by cell-specific, microtubule ...
Catherine D. Thaler, Leah T. Haimo
openaire   +3 more sources

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