A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies. [PDF]
, 2017 Control of organellar assembly and function is critical to eukaryotic homeostasis and survival. Gle1 is a highly conserved regulator of RNA-dependent DEAD-box ATPase proteins, with critical roles in both mRNA export and translation.
Akef, Abdalla +2 more
core +1 more source
Spatial Organization of the Cytoskeleton enhances Cargo Delivery to Specific Target Areas on the Plasma Membrane of Spherical Cells [PDF]
, 2016 Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal ...
Hafner, Anne E., Rieger, Heiko
core +2 more sources
European Journal of Cell Biology, 2022 To understand general features in evolution of kinetochore organization, investigating a wide range of mitotic mechanisms in various non-model eukaryotes is necessary.
Pavla Tůmová +2 more
doaj +1 more source
Fission yeast MOZART1/Mzt1 is an essential γ-tubulin complex component required for complex recruitment to the microtubule organizing center, but not its assembly. [PDF]
Mol Biol Cell, 2013 Masuda H, Mori R, Yukawa M, Toda T.
europepmc +3 more sources
Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates. [PDF]
, 2017 As microtubule-organizing centers of animal cells, centrosomes guide the formation of the bipolar spindle that segregates chromosomes during mitosis.
Antkowiak, Mark +11 more
core +2 more sources
mSphere, 2018 Kinetochore clustering, frequently observed in yeasts, plays a key role in genome organization and chromosome segregation. In the absence of the metaphase plate arrangement, kinetochore clustering in yeast species is believed to facilitate timely ...
Vikas Yadav, Kaustuv Sanyal
doaj +1 more source
Elastic properties of grafted microtubules [PDF]
, 2005 We use single-particle tracking to study the elastic properties of single microtubules grafted to a substrate. Thermal fluctuations of the free microtubule's end are recorded, in order to measure position distribution functions from which we calculate ...
A. Jonas +34 more
core +4 more sources
3D-Structured Illumination Microscopy of Centrosomes in Human Cell Lines
Bio-Protocol, 2022 The centrosome is the main microtubule-organizing center of animal cells, and is composed of two barrel-shaped microtubule-based centrioles embedded in protein dense pericentriolar material.
Kari-Anne Frikstad +4 more
doaj +1 more source
Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex. [PDF]
, 2014 The binucleate pathogen Giardia intestinalis is a highly divergent eukaryote with a semiopen mitosis, lacking an anaphase-promoting complex/cyclosome (APC/C) and many of the mitotic checkpoint complex (MCC) proteins.
Cande, W Zacheus, Vicente, Juan-Jesus
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Centrosomal and Non-Centrosomal Microtubule-Organizing Centers (MTOCs) in Drosophila melanogaster
Cells, 2018 The centrosome is the best-understood microtubule-organizing center (MTOC) and is essential in particular cell types and at specific stages during Drosophila development.
Marisa M. L. Tillery +4 more
doaj +1 more source