Results 101 to 110 of about 242,523 (302)
Tunneling Nanotube‐Mediated Transcellular Autophagy Alleviates Cadmium Induced Hepatocyte Injury
Advanced Science, EarlyView.ROS accumulation is an important upstream signal for activating transcellular autophagy. Incomplete autophagy and TNT formation are necessary conditions for activating transcellular autophagy, and the disruption of the autophagic fusion mechanism is a trigger for activating transcellular autophagy.
Tao Wang +13 more
wiley +1 more source
607 DEFECTIVE MICROTUBULE RELATED FUNCTIONS OF PHAGOCYTES IN GLUTATHIONE PEROXIDASE DEFICIENT RATS [PDF]
, 1978 Richard E. Harris +2 more
openalex +1 more source
Structure and behaviour of the sperm terminal filament [PDF]
, 1982 Light- and electron-microscopic observations of Ciona and Lytechinus spermatozoa show a thin terminal filament at the distal end. The terminal filament is 5-6 microns long and contains the two central microtubules and a variable number of A-tubule ...
Brokaw, C. J., Omoto, C. K.
core
Advanced Science, EarlyView.pMM‐PCL, made up of pretreated macrophage menbrane and polycaprolactone, boasts the adsorption of harmful myelin debris in the microenvironment of spinal cord injury. Abstract After spinal cord injury (SCI), a mass of myelin debris derived from injured myelin sheath will be consistently generated and induce macrophages to be foam cells.
Yuchen Zhou +7 more
wiley +1 more source
Inhibition by griseofulvin of microtubule assembly in vitro [PDF]
, 1976 Anne Roobol +2 more
openalex +1 more source
Advanced Science, EarlyView.This research introduces a novel approach to enhance neuroregeneration following Traumatic Brain Injury (TBI). Extracellular Vesicles (EVs) are isolated from human neural progenitor cells under hypoxic conditions, leading to enhanced expression of neurogenic and angiogenic factors.
Joshua B. Stein +9 more
wiley +1 more source
Autophagy‐Mediated Suppression of Tumor Growth by Food‐Grade Lipid Nanoparticles in Mice
Advanced Science, EarlyView.This work reveals a novel extracellular nanoparticle transport and metabolic pathway. Following cellular uptake, Food‐grade lipid nanoparticles (FLNs) selectively fuse with lipid droplets (LDs) rather than lysosomes, driving LDs accumulation. This process activates autophagy through the AMPK‐mTOR‐ULK1 signaling axis, facilitating tumor progression ...
Chenglu Peng +10 more
wiley +1 more source
Advanced Science, EarlyView.ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen +17 more
wiley +1 more source
MICROTUBULE SURFACE LATTICE AND SUBUNIT STRUCTURE AND OBSERVATIONS ON REASSEMBLY [PDF]
, 1974 Harold Erickson
openalex +1 more source
Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene
Advanced Science, EarlyView.Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan +15 more
wiley +1 more source