Results 81 to 90 of about 148,484 (307)

Does usnic acid affect microtubules in human cancer cells?

Brazilian Journal of Biology
Usnic acid, a lichen metabolite, is known to exert antimitotic and antiproliferative activities against normal and malignant human cells. Many chemotherapy agents exert their activities by blocking cell cycle progression, inducing cell death through ...
MA. O'Neill, M. Mayer, KE. Murray, HML. Rolim-Santos, NS. Santos-Magalhães, AM. Thompson, VCL. Appleyard   +6 more
doaj   +1 more source

Analysis of Water-Soluble Proteins by Two-Dimensional Electrophoresis in the Encystment Process of Colpoda cucullus Nag-1 and Cytoskeletal Dynamics

Acta Protozoologica, 2021
Assays of protein contained in water-soluble fraction of encysting cells Colpoda cucullus Nag-1 by two-dimensional electrophoresis (2-D PAGE) and mass spectrometry (MS) revealed that the amount of β ...
Yoichiro Sogame, Katsuhiko Kojima, Toshikazu Takeshita, Shiho Kikuchi, Yuto Shimada, Rikiya Nakamura, Mikihiko Arikawa, Seiji Miyata, Eiji Kinoshita, Futoshi Suizu, Tatsuomi Matsuoka   +10 more
doaj   +1 more source

Vibrations in Microtubules [PDF]

Journal of Biological Physics, 1997
Vibrations in microtubules and actin filaments are analysed using amethod similar to that employed for description of lattice vibrationsin solid state physics. The derived dispersion relations show thatvibrations in microtubules can have optical and acoustical branches.The highest frequency of vibrations in microtubules and in actinfilaments is of the ...
J, Pokorný, F, Jelínek, V, Trkal, I, Lamprecht, R, Hölzel   +4 more
openaire   +2 more sources

Visualization of cell microtubules in their native state. [PDF]

, 2007
BACKGROUND INFORMATION Over the past decades, cryo-electron microscopy of vitrified specimens has yielded a detailed understanding of the tubulin and microtubule structures of samples reassembled in vitro from purified components.
Achilleas S. Frangakis, Grabenbauer, M., Eltsov, Mikhail, Dubochet, J., Mikhail Eltsov, Markus Grabenbauer, Frangakis, Achilleas S, Anne‐Marie Glynn, Denis Chrétien, Frangakis, A., Frangakis, A.S., Goldie, Kenneth N, Dubochet, Jacques, Jacques Dubochet, Goldie, K., Thomas, Daniel, Kenneth N. Goldie, Chrétien, Denis, Goldie, K.N., Daniel Thomas, Grabenbauer, Markus, Zuber, Benoît, Benoît Zuber, Cédric Bouchet‐Marquis, Glynn, A.M., Glynn, Anne-Marie, Glynn, A., Chretien, D., Bouchet-Marquis, Cédric, Bouchet-Marquis, C., Zuber, B., Thomas, D., Eltsov, M., Thomas D, Bouchet-Marquis C, Dubochet J, Eltsov M, Zuber B, Frangakis AS, Glynn AM, Grabenbauer M, Chrétien D, Goldie KN   +42 more
core   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Folding of the Tau protein on microtubules. [PDF]

, 2015
Microtubules are regulated by microtubule-associated proteins. However, little is known about the structure of microtubule-associated proteins in complex with microtubules.
Biernat, J., Jaremko, M., Jaremko, L., Zweckstetter, M., Kadavath, H., Mandelkow, E.   +5 more
core   +2 more sources

Nitric oxide stabilizes microtubules during neuronal differentiation

, 2010
Nitric oxide (NO) is a signalling molecule in the nervous system playing a role in neurotransmitter release, synaptic plasticity, excitability, learning, differentiation and development.
G. Tedeschi, G. Cappelletti, C. Ronchi, D. Cartelli   +3 more
core   +1 more source

Acetylated alpha-tubulin in Trypanosoma cruzi: immunocytochemical localization

Memorias do Instituto Oswaldo Cruz, 1993
We have used monoclonal antibodies specific for acetylated and non-acetylated alpha-tubulin to localize microtubules containing acetylated alpha-tubulin in all developmental forms of the life cycle of Trypanosoma cruzi.
Thais Souto-Padron, Narcisa L. Cunha e Silva, Wanderley de Souza   +2 more
doaj   +1 more source

A study of M0R1/GEM1 and kinl-like kinesins arabidopsis [PDF]

, 2004
Microtubules perform essential functions in eukaryotic cells and, with other cytoskeletal elements, are involved in diverse cellular processes. Plant cells construct four microtubule arrays; There are two cortical arrays, the interphase cortical array ...
Hawkins, Timothy James
core  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source