Results 81 to 90 of about 215,535 (300)
Kinesins relocalize the chromosomal passenger complex to the midzone for spindle disassembly. [PDF]
, 2018 Mitotic spindle disassembly after chromosome separation is as important as spindle assembly, yet the molecular mechanisms for spindle disassembly are unclear.
Avunie-Masala +43 more
core +1 more source
Pivoting of microtubules driven by minus-end-directed motors leads to spindle assembly
BMC Biology, 2019 Background At the beginning of mitosis, the cell forms a spindle made of microtubules and associated proteins to segregate chromosomes. An important part of spindle architecture is a set of antiparallel microtubule bundles connecting the spindle poles. A
Lora Winters +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
A brief introduction to the model microswimmer {\it Chlamydomonas reinhardtii} [PDF]
, 2016 The unicellular biflagellate green alga {\it Chlamydomonas reinhardtii} has been an important model system in biology for decades, and in recent years it has started to attract growing attention also within the biophysics community.
Contino, Matteo +2 more
core +2 more sources
Specific in vivo labeling of tyrosinated α-tubulin and measurement of microtubule dynamics using a GFP tagged, cytoplasmically expressed recombinant antibody. [PDF]
PLoS ONE, 2013 GFP-tagged proteins are used extensively as biosensors for protein localization and function, but the GFP moiety can interfere with protein properties. An alternative is to indirectly label proteins using intracellular recombinant antibodies (scFvs), but
Lynne Cassimeris +4 more
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Mathematics, 2016 In this research article, we present exact solutions with parameters for two nonlinear model partial differential equations(PDEs) describing microtubules, by implementing the exp(−Φ(ξ))-Expansion Method ...
Nur Alam, Fethi Bin Muhammad Belgacem
doaj +1 more source
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Modeling the Effects of Drug Binding on the Dynamic Instability of Microtubules
, 2011 We propose a stochastic model that accounts for the growth, catastrophe and rescue processes of steady state microtubules assembled from MAP-free tubulin.
Correia J J +8 more
core +1 more source
Emerging roles for microtubules in angiosperm pollen tube growth highlight new research cues
Frontiers in Plant Science, 2015 In plants, actin filaments have an important role in organelle movement and cytoplasmic streaming. Otherwise microtubules have a role in restricting organelles to specific areas of the cell and in maintaining organelle morphology. In somatic plant cells,
Alessandra eMoscatelli +2 more
doaj +1 more source