Results 141 to 150 of about 108,812 (267)

A cryo-EM processing pipeline for microtubules using CryoSPARC. [PDF]

Acta Crystallogr D Struct Biol
Zhang D, Muñoz-Hernández H, Filipcik P, Sejwal K, Xu Y, Choi SR, Steinmetz MO, Wieczorek M.   +7 more
europepmc   +1 more source

Segmented Therapeutic Delivery via Acoustic Microbubble Relay

Advanced Intelligent Systems, EarlyView.
An acoustically driven, modular segmented delivery system is presented to overcome mechanical limitations of conventional microcatheters. Oscillating microbubbles generate directional streaming that enables continuous, targeted transport across open, angled segments.
Lei Wang, Yiyang Tang, Yiqiang Wu, Xin Zhang, Tianshi Lyu, Zhen Hua, Tian‐Yun Huang   +6 more
wiley   +1 more source

Microtubular Disruption Alters Intestinal Permeability in Murine Neonatal Anemic Intestine. [PDF]

Anemia
Balamurugan MA, Ramatchandirin B, Raj JG, Subrramanya A, Azeem S, Lawal ZD, Ferris MM, Meister E, MohanKumar K.   +8 more
europepmc   +1 more source

An Adult Presentation of KIF11‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42‐year‐old female presenting with a de novo single‐amino acid in‐frame deletion in the KIF11 gene (c.1294_1296del; p ...
Thrishna Chathurvedula, Juvy Rabelas, Kareem Touleimat, Elaine Marchi, Ruhi Shah, Shaydah Kheradmand, Kuldeep Singh, Karen Amble, Gholson J. Lyon   +8 more
wiley   +1 more source

Precision Switching and Coupled Motion in a [3]Rotaxane Molecular Machine

Angewandte Chemie, EarlyView.
A [3]rotaxane, composed by two crown ether macrocycles and an axle presenting three recognition sites, is operated through both chemical and electrochemical stimuli. The position of the macrocycles is precisely controlled by sequential stimulation and the processes are fully reversible. The characterization of the system revealed the macrocycles affect
Leonardo Andreoni, Jessica Groppi, Alberto Credi, Serena Silvi   +3 more
wiley   +2 more sources

Proteomic and transcriptomic signatures of cytoskeletal remodeling during morphogenesis in the basal metazoan <i>Halisarca dujardinii</i> (Porifera). [PDF]

Front Cell Dev Biol
Kotov AA, Finoshin AD, Adameyko KI, Zubarev VM, Burakov AV, Sabirov MS, Mikhailov KV, Ziganshin RH, Gornostayev NG, Erokhov PA, Ezhova MA, Shagimardanova EI, Mikhailov VS, Kravchuk OI, Lyupina YV.   +14 more
europepmc   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Both sides now: modeling motor regulation of microtubule length at both ends. [PDF]

Phys Biol
Ciocanel MV, Karamched BR.
europepmc   +1 more source

ISOLATED MICROTUBULES [PDF]

The Journal of Cell Biology, 1965
openaire   +2 more sources

Cardiovascular Exercise Drives Neuroprotection in a Mouse Model of Spinocerebellar Ataxia 1 Via Rescue of Aberrant Splicing

Annals of Neurology, EarlyView.
Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto, Michael Bonomo, Brianna S. Nelthrope, Benjamin D. Carr, Emma Palmer, Mariana Sierra, Ilkim Erturk, David Peppercorn, Eleonor Cox, Tiare K. Vasconcellos, Henry L. Paulson, Hannah K. Shorrock, Sharan R. Srinivasan   +12 more
wiley   +1 more source