Results 171 to 180 of about 225,378 (345)
Advanced Science, EarlyView.Different from mitosis, the female meiosis undergoes asymmetric division that produces haploid oocytes and polar body, which is essential for retaining maternal components to support subsequent fertilization and embryo development. However, the underlying mechanisms are still largely unknown.
Yu Li +6 more
wiley +1 more source
Autophagy‐Mediated Suppression of Tumor Growth by Food‐Grade Lipid Nanoparticles in Mice
Advanced Science, EarlyView.This work reveals a novel extracellular nanoparticle transport and metabolic pathway. Following cellular uptake, Food‐grade lipid nanoparticles (FLNs) selectively fuse with lipid droplets (LDs) rather than lysosomes, driving LDs accumulation. This process activates autophagy through the AMPK‐mTOR‐ULK1 signaling axis, facilitating tumor progression ...
Chenglu Peng +10 more
wiley +1 more source
Advanced Science, EarlyView.A wireless‐charging sustained oxygen release from conductive microgels (SOCO) served as an antenna and an on‐demand O2 release for nerve regeneration is developed. Introducing “electromagnetic messenger”, using external alternating magnetic field (AMF) to enhance catalytic oxygen release and electrical stimulation to promote the reconstruction of blood
Hoi Man Iao +15 more
wiley +1 more source
Advanced Science, EarlyView.ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen +17 more
wiley +1 more source
The Mn-motif protein MAP6d1 assembles ciliary doublet microtubules. [PDF]
Nat CommunGopal D +10 more
europepmc +1 more source
MICROTUBULE BIOGENESIS AND CELL SHAPE IN OCHROMONAS [PDF]
, 1973 G. Benjamin Bouck, David L. Brown
openalex +1 more source
Genetic Impacts on the Structure and Mechanics of Cellulose Made by Bacteria
Advanced Science, EarlyView.A genetic mutation in a protease of a cellulose‐overproducing evolved bacterium significantly affects the proteome, structure, and mechanical properties of bio‐fabricated cellulose pellicles. By overexpressing synthase proteins that build the cellulose‐forming biological machinery of the cell, the evolved bacterium generates dense, stiff, and strong ...
Julie M. Laurent +8 more
wiley +1 more source
Estradiol pauses microtubule growth without increased incidence of catastrophe events. [PDF]
Commun BiolOgren AN +7 more
europepmc +1 more source
Human chromosomes and centrioles as nucleating sites for the in vitro assembly of microtubules from bovine brain tubulin. [PDF]
, 1975 Manley McGill, B. R. Brinkley
openalex +1 more source
Advanced Science, EarlyView.Iron‐induced lipid peroxidation of phosphatidylethanolamine (PE) species is the key driver of ferroptosis. The authors discovered that PHOSPHO1 lowers the level of PE in retinal pigment epithelial cells thus reducing the formation of lipid peroxides. Lowering PE levels can also prevent the creation of autolysosomes, reduce the production of free iron ...
Zhiyang Chen +19 more
wiley +1 more source