Results 191 to 200 of about 215,535 (300)

Machine Learning‐Based Estimation of Experimental Artifacts and Image Quality in Fluorescence Microscopy

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The use of image quality metrics in combination with machine learning enables automatic image quality assessment for fluorescence microscopy images. The method can be integrated into the experimental pipeline for optical microscopy and utilized to classify artifacts in experimental images and to build quality rankings with a reference‐free approach ...
Elena Corbetta, Thomas Bocklitz
wiley   +1 more source

Microenvironmental stiffness directs microtubule perturbation in chondrocyte mitosis via ILK-refilinB/Smad3 axis. [PDF]

Bone Res
Duan M, Zhou C, Su G, Zhang C, Ren J, Chi Q, Liu X, Yang L, Bai H, Zeng YC, Kim S, Zhai Y, Oh CY, Ye AY, Chen Y, Si L, Liu X, Xie J.   +17 more
europepmc   +1 more source

SuperResNET: Model‐Free Single‐Molecule Network Analysis Software Achieves Molecular Resolution of Nup96

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
SuperResNET is a powerful integrated software that reconstructs network architecture and molecular distribution of subcellular structures from single molecule localization microscopy datasets. SuperResNET segments the nuclear pore complex and corners, extracts size, shape, and network features of all segmented nuclear pores and uses modularity analysis
Yahongyang Lydia Li, Ismail M. Khater, Christian Hallgrimson, Ben Cardoen, Timothy H. Wong, Ghassan Hamarneh, Ivan R. Nabi   +6 more
wiley   +1 more source

Neuronal Calcium Signaling and Cytoskeletal Dynamics in Neurodegeneration. [PDF]

Int J Mol Sci
Rakovskaya A, Volkova E, Pchitskaya E.
europepmc   +1 more source

Genome Sequencing in 19 Families With Bladder Exstrophy and Epispadias Complex Indicates Involvement of the ADGR‐Gene Family

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Bladder exstrophy and epispadias complex (BEEC) is one of the most severe congenital malformations of the urogenital tract, significantly impacting continence, sexual function, and renal function. To date, the only recurrent genetic aberration identified is the 22q.11.2 microduplication, but several candidate regions and genes including ...
Agneta Nordenskjöld, Samara Alm, Jesper Eisfeldt, Jia Cao, Magnus Anderberg, Gillian Barker, Hans Matsson, Gundela Holmdahl, Anna Lindstrand, Kristina Lagerstedt‐Robinson   +9 more
wiley   +1 more source

Developmental Remodeling of the Auditory Hair Cell Cuticular Plate Defines Transient and Mature Structural Domains. [PDF]

Cells
Liu A, Gao S, Du Y, Dou Z, Liu W, Xu S, Sun W, Li X, Li J, Liu Q, Jin Y.   +10 more
europepmc   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson, Maria Teresa Fiorenza   +1 more
wiley   +1 more source

The γ-TuRC: mastermind of multipurpose actions at the centrosome. [PDF]

Cell Mol Life Sci
Mukhopadhyay S, Gao Q, Manna TK, Schiebel E.   +3 more
europepmc   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation. [PDF]

Elife
Hotta T, Pimm ML, Thomas EC, Yue Y, DeLear P, Blasius L, Cianfrocco MA, DeSantis ME, Horiuchi R, Higaki T, Sept D, Ohi R, Verhey KJ.   +12 more
europepmc   +1 more source