Results 211 to 220 of about 108,812 (267)

Regulation of microtubule abundance and minus end dynamics by Katanin, CAMSAPs, WDR47 and kinesin-13

open access: yes
Rai D   +7 more
europepmc   +1 more source

A biochemical probe for microtubule lattice integrity uncovers motor-caused lattice damage

open access: yes
Egoldt C   +6 more
europepmc   +1 more source
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Isolation of Microtubules and Microtubule Proteins

Current Protocols in Cell Biology, 2008
AbstractThis unit describes various protocols for the isolation and purification of the main constituents of microtubules, chiefly α‐ and β‐tubulin, and the most significant microtubule associated proteins (MAPs), specifically MAP1A, MAP1B, MAP2, and tau.
Ávila, Jesús   +3 more
openaire   +3 more sources

Microtubules and microtubule-associated proteins

Current Opinion in Cell Biology, 1995
Microtubule research is becoming increasingly diverse, reflecting the many isoforms and modifications of tubulin and the many proteins with which microtubules interact. Recent advances are particularly visible in four areas: microtubule motor proteins (their structures, stepping modes, and forces); microtubule nucleation (the roles of centrosomes and ...
Mandelkow, Eckhard, Mandelkow, Eva
openaire   +3 more sources

Microtubules, microtubule-interfering agents and apoptosis

Apoptosis, 2003
Microtubules are dynamic polymers that play crucial roles in a large number of cellular functions. Their pivotal role in mitosis makes them a target for the development of anticancer drugs. Microtubule-damaging agents suppress microtubule dynamics, leading to disruption of the mitotic spindle in dividing cells, cell cycle arrest at M phase, and late ...
Mollinedo, Faustino, Gajate, Consuelo
openaire   +3 more sources

Microtubule-Associated Proteins and the Flexibility of Microtubules

Biochemistry, 1995
Experiments were conducted to learn whether the binding of microtubule-associated proteins (MAPs) to microtubules alters the flexibility of the microtubules. Flexibility was measured in vitro by two established techniques. The first employed measurement of the bending of the microtubule in a flow of buffer; the second involved repeated measurement of ...
J C, Kurz, R C, Williams
openaire   +2 more sources

Microtubule nucleation

Current Opinion in Cell Biology, 2003
Microtubule nucleation is the process in which several tubulin molecules interact to form a microtubule seed. Microtubule nucleation occurs spontaneously in purified tubulin solutions, and molecular intermediates between tubulin dimers and microtubules have been identified.
Didier, Job   +2 more
openaire   +2 more sources

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