Worm orthologues of cytokinesis-associated proteins CIT and ASPM regulate neuronal microtubule dynamics and polarity in C. elegans. [PDF]
Sharma S +5 more
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Quantum theories of consciousness: a critical review of feasibility, philosophical sufficiency, and empirical testability. [PDF]
Ma X, Wang A.
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Regulation of microtubule abundance and minus end dynamics by Katanin, CAMSAPs, WDR47 and kinesin-13
Rai D +7 more
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A biochemical probe for microtubule lattice integrity uncovers motor-caused lattice damage
Egoldt C +6 more
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Gαi2 coordinates neuronal microtubule and neurofilament networks to regulate axon initiation in vivo
Higgs VE +4 more
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Isolation of Microtubules and Microtubule Proteins
Current Protocols in Cell Biology, 2008AbstractThis unit describes various protocols for the isolation and purification of the main constituents of microtubules, chiefly α‐ and β‐tubulin, and the most significant microtubule associated proteins (MAPs), specifically MAP1A, MAP1B, MAP2, and tau.
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Microtubules and microtubule-associated proteins
Current Opinion in Cell Biology, 1995Microtubule research is becoming increasingly diverse, reflecting the many isoforms and modifications of tubulin and the many proteins with which microtubules interact. Recent advances are particularly visible in four areas: microtubule motor proteins (their structures, stepping modes, and forces); microtubule nucleation (the roles of centrosomes and ...
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Microtubules, microtubule-interfering agents and apoptosis
Apoptosis, 2003Microtubules are dynamic polymers that play crucial roles in a large number of cellular functions. Their pivotal role in mitosis makes them a target for the development of anticancer drugs. Microtubule-damaging agents suppress microtubule dynamics, leading to disruption of the mitotic spindle in dividing cells, cell cycle arrest at M phase, and late ...
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Microtubule-Associated Proteins and the Flexibility of Microtubules
Biochemistry, 1995Experiments were conducted to learn whether the binding of microtubule-associated proteins (MAPs) to microtubules alters the flexibility of the microtubules. Flexibility was measured in vitro by two established techniques. The first employed measurement of the bending of the microtubule in a flow of buffer; the second involved repeated measurement of ...
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Microtubule nucleation is the process in which several tubulin molecules interact to form a microtubule seed. Microtubule nucleation occurs spontaneously in purified tubulin solutions, and molecular intermediates between tubulin dimers and microtubules have been identified.
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