An Indole Dearomatization Strategy for the Synthesis of Pseudo‐Natural Products
The indole moiety is a privileged fragment that frequently populates existing bioactive compound collections. We describe the development of an indole‐dearomatization sequence and its application for library expansion of a collection of indole‐containing pseudo‐NPs.
Joseph G.F. Hoock+13 more
wiley +1 more source
A Benzodiazepine-Derived Molecule That Interferes with the Bio-Mechanical Properties of Glioblastoma-Astrocytoma Cells Altering Their Proliferation and Migration. [PDF]
Ragazzini G+14 more
europepmc +1 more source
MICROTUBULE SURFACE LATTICE AND SUBUNIT STRUCTURE AND OBSERVATIONS ON REASSEMBLY [PDF]
Harold Erickson
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ABSTRACT Alzheimer's disease (AD) is prevalent in the elderly population and characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), composed of tau proteins, and extracellular deposition of beta‐amyloid protein (Aβ). The present study aimed to investigate the neuroprotective effects of melatonin on Aβ42‐induced AD‐like ...
Jiraporn Panmanee+11 more
wiley +1 more source
Elongator is a microtubule polymerase selective for polyglutamylated tubulin. [PDF]
Planelles-Herrero VJ+9 more
europepmc +1 more source
Interactions of a photoaffinity analog of GTP with the proteins of microtubules.
Robert L. Geahlen, Boyd E. Haley
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Cyclic AMP, the microtubule-microfilament system, and cancer. [PDF]
Theodore T. Puck
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CAMSAP2 is required for bridging fiber assembly to ensure mitotic spindle assembly and chromosome segregation in human epithelial Caco-2 cells. [PDF]
Nishizawa N+4 more
europepmc +1 more source
Microtubule assembly: Some possible regulatory mechanisms [PDF]
J.B. Olmsted+4 more
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Biomass Sources, synthesis techniques, structures, applications, and contribution toward SDG goals of biomass‐derived carbon nanomaterials. ABSTRACT Plant life has dominated this planet from the beginning of time. With over 82% of biomass (BM) coming from plants, primarily trees, plants are the dominant form of life on Earth.
A. F. M. Fahad Halim+5 more
wiley +1 more source