Results 251 to 260 of about 148,484 (307)

A MAP-SNARE interaction links cortical microtubules to the exocytic fusion machinery during auxin-dependent growth remodeling. [PDF]

Sci Adv
Deng J, Qin J, Wang P, Zhao X, Zhang X, Fu J, Mao T, Wang X.   +7 more
europepmc   +1 more source

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

Cytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook, Edna C. Hardeman, Peter W. Gunning   +2 more
wiley   +1 more source

Condensation of MATCAP promotes CENP-E-dependent chromosome congression in mitosis. [PDF]

Nat Commun
Yang T, Hu W, Xu P, Li H, Zhang Y, Xiong F, Li Y, Xu C, Ruan K, Hou Z, Wang Z, Zhang L, Yao X, Xiang S, Jiang K, Liu X.   +15 more
europepmc   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

CsMT: a robust and streamlined CryoSPARC workflow for cryo-EM reconstruction of microtubules. [PDF]

Acta Crystallogr D Struct Biol
Alagha T, Arin A, Vangos N, Goodey-Parfitt H, Ngo HN, Dau NN, Nguyen MH, Legal T, Cianfrocco MA, Bui KH.   +9 more
europepmc   +1 more source

Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1

Cytoskeleton, EarlyView.
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley   +1 more source

Microtubules in Mitosis.

Cell Structure and Function, 1994
openaire   +3 more sources

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Eukaryotic-like microtubules and dynamic instability of Asgard archaeal tubulins. [PDF]

Sci Adv
Löwe J, von Kügelgen A, Planelles-Herrero VJ, McAndrew MBL, Oliva MA, Vosseberg J, Köstlbacher S, Dharamshi JE, Appler KE, MacLeod FI, Nobs SJ, Jørgensen SL, Burns BP, Baker BJ, Bharat TAM, Derivery E, Tamarit D, Ettema TJG.   +17 more
europepmc   +1 more source

Bottom-Up Synthesis and Active Assembly of DNA Networks by Biomolecular Nanomachines. [PDF]

Small
Afroze F, Archer RJ, Mustakim M, Das R, Kabir AMR, Miura Y, Rashid R, Sada K, Hiraiwa T, Nomura SM, Hamada S, Kakugo A.   +11 more
europepmc   +1 more source