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Microtubules and microtubule-associated proteins

Current Opinion in Cell Biology, 1995
Microtubule research is becoming increasingly diverse, reflecting the many isoforms and modifications of tubulin and the many proteins with which microtubules interact. Recent advances are particularly visible in four areas: microtubule motor proteins (their structures, stepping modes, and forces); microtubule nucleation (the roles of centrosomes and ...
Mandelkow, Eckhard, Mandelkow, Eva
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Microtubule nucleation

Current Opinion in Cell Biology, 2003
Microtubule nucleation is the process in which several tubulin molecules interact to form a microtubule seed. Microtubule nucleation occurs spontaneously in purified tubulin solutions, and molecular intermediates between tubulin dimers and microtubules have been identified.
Didier, Job   +2 more
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Microtubule dynamics

Cellular and Molecular Life Sciences, 2001
Microtubules are fibrous elements in the cytoplasm of eukaryotic cells, where they perform a wide variety of functions. Microtubules are major organizers of the cell interior and are vitally involved in motility events such as chromosome migration during cell division. To fulfill their physiological function, microtubule arrays have to undergo dramatic
O, Valiron, N, Caudron, D, Job
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Ordering microtubules

BioEssays, 1997
AbstractHow do cells order their cytoplasm? While microtubule organizing centers have long been considered essential to conferring order by virtue of their microtubule nucleating activity, attention has currently refocused on the role that microtubule motors play in organizing microtubules.
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Intranuclear Microtubules

Science, 1966
Intranuclear microtubules are a regular feature of spermatocyte meiosis in a crane fly ( Nephrotoma suturalis Loew).
O, Behnke, A, Forer
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Microtubule dynamics

Current Opinion in Cell Biology, 1992
Although compelling evidence has been obtained for heterogeneity in the structure of subunits in microtubules, it has not been possible to prove that this results from the presence of tubulin-GDP and tubulin-GTP in polymers. There are reasons to exclude the existence of even a monolayer of tubulin-GTP subunits at microtubule ends.
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