Results 261 to 270 of about 249,538 (351)

Vinpocetine Overcomes Paclitaxel Resistance in a Triple‐Negative Breast Cancer Cell Line

open access: yesCell Biology International, EarlyView.
ABSTRACT Paclitaxel is a first‐line treatment for triple‐negative breast cancer (TNBC), but its efficacy is commonly limited by tumor‐cell resistance. Vinpocetine is a well‐tolerated dietary supplement with pleiotropic cellular effects, including potential anti‐tumor activity.
Hsiao‐Hui Kuo   +3 more
wiley   +1 more source

The Aging Gut–Brain Axis: Effects of Dietary Polyphenols and Metal Exposure

open access: yesChronic Diseases and Translational Medicine, EarlyView.
The influence of gut microbiota on brain health ABSTRACT Diet provides essential metals, which are required for the growth, development, and well‐functioning of the body. Nonetheless, some natural and human activities add toxic heavy metals to the diet, consequently introducing them to our bodies, resulting in several disorders and death. The intestine,
Luqi Cao   +7 more
wiley   +1 more source

The Mn-motif protein MAP6d1 assembles ciliary doublet microtubules. [PDF]

open access: yesNat Commun
Gopal D   +10 more
europepmc   +1 more source

TRiC Is a Structural Component of Mammalian Sperm Axonemes

open access: yesCytoskeleton, EarlyView.
ABSTRACT The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo‐electron microscopy studies of axonemes from diverse mammalian cell types led to the surprising discovery that a fully assembled TRiC chaperonin is a structural component of mammalian sperm flagella, where it is tethered to the radial ...
Alan Brown   +3 more
wiley   +1 more source

<i>C. elegans</i> kinesin 1 regulates meiotic spindle size. [PDF]

open access: yesMicroPubl Biol
Do R, Aquino A, McNally F.
europepmc   +1 more source

Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly

open access: yesCytoskeleton, EarlyView.
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley   +1 more source

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