Results 51 to 60 of about 193,314 (299)

Pathophysiology of Coronary Microvascular Dysfunction

Circulation Journal, 2022
Ischemic heart disease (IHD) is commonly recognized as the consequence of coronary atherosclerosis and obstructive coronary artery disease (CAD). However, a significant number of patients may present angina or myocardial infarction even in the absence of any significant coronary artery stenosis and impairment of the coronary microcirculation has been ...
Filippo, Crea, Rocco A, Montone, Riccardo, Rinaldi   +2 more
openaire   +3 more sources

Single Nucleotide Polymorphisms in Coronary Microvascular Dysfunction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Coronary microvascular dysfunction is an underdiagnosed pathologic process that is associated with adverse clinical outcomes. There are data to suggest that coronary microvascular dysfunction, in some cases, may be genetically determined.
Andrew P. Stein, Jonathan Harder, Henry R. Holmes, C. Noel Bairey Merz, Carl J. Pepine, Ellen C. Keeley   +5 more
doaj   +1 more source

Microvascular dysfunction after myocardial ischemia [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 1995
Endothelium-mediated relaxation and smooth muscle function in large coronary arteries are resistant to prolonged global ischemia. We used a small-vessel myograph to test the hypothesis that small intramyocardial artery endothelium and smooth muscle function have greater sensitivity to ischemic injury than large artery endothelium and smooth muscle ...
Dignan, Rebecca J., Kadletz, Margit, Dyke, Cornelius M., Lutz, Harry A., Yeh, Thomas, Wechsler, Andrew S.   +5 more
openaire   +2 more sources

Role of T‐Cell Dysfunction, Inflammation, and Coagulation in Microvascular Disease in HIV

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background Compared to uninfected adults, HIV‐infected adults on antiretroviral therapy are at increased risk of cardiovascular disease. Given the increase in T‐cell dysfunction, inflammation, and coagulation in HIV infection, microvascular dysfunction ...
Arjun Sinha, Yifei Ma, Rebecca Scherzer, Sophia Hur, Danny Li, Peter Ganz, Steven G. Deeks, Priscilla Y. Hsue   +7 more
doaj   +1 more source

Non-pharmacological Treatment of Refractory Angina and Microvascular Angina

Biomedicines, 2020
Refractory angina (RA) is defined as debilitating anginal symptoms despite the optimal guideline-directed combination of medical, percutaneous, and surgical therapies.
Kudrat Rakhimov, Tommaso Gori
doaj   +1 more source

Angiogenic and angiostatic factors in renal scleroderma-associated vasculopathy [PDF]

, 2017
BACKGROUND: The angiogenesis in systemic sclerosis (SSc) is impaired. An imbalance of pro-angiogenic factors and angiogenesis inhibitors has been implicated in the progression of peripheral microvascular damage, defective vascular repair and fibrosis ...
Afeltra, Antonella M. Vittoria, Amoroso, Antonio, Barbano, Biagio, Cianci, Rosario, Gigante, Antonietta, Margiotta, Domenico, Navarini, Luca, Rosato, Edoardo   +7 more
core   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Microvascular Dysfunction Following Cardioplegic Arrest and Cardiopulmonary Bypass: Impacts of Diabetes and Hypertension

Biomedicines
Cardioplegic arrest and cardiopulmonary bypass (CP/CPB) are known to engender microvascular dysfunction in patients undergoing cardiac surgery. These effects are significantly varied by patient comorbidities including diabetes and hypertension.
Meghamsh Kanuparthy, Rishik Manthana, Himanshu Kaushik, Kathy Xiang, Jad Hamze, David Marimekala, Jun Feng, Frank W. Sellke   +7 more
doaj   +1 more source

P27 Prevalence of microvascular dysfunction in diabetic patients with normal gated spect

Revista de la Sociedad Argentina de Diabetes, 2020
Introduction: Patients with diabetes have an increased risk for cardiovascular events. Microvascular dysfunction is an early sign of damage, associated with poorer prognosis in these patients, including those with normal gated SPECT.
Hugo Daniel Sanabria, María Inés Vera, Santiago Bruzone, Gustavo Javier Daquarti, Juliana Mociulsky, Alejandro Meretta, María Cristina Faingold, Isaac Sinay   +7 more
doaj   +1 more source

Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. [PDF]

, 2014
BackgroundIndividuals with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease, partly due to systemic inflammation and endothelial dysfunction.
Del Puerto, Gus, Ganz, Peter, Graf, Jonathan, Grunfeld, Carl, Hsue, Priscilla Y, Imboden, John, Nitta, Elaine, Scherzer, Rebecca, Schnell Heringer, Amanda, Shigenaga, Judy, Wu, Yuaner   +10 more
core   +2 more sources