Results 31 to 40 of about 132,725 (259)

Coronary endothelial dysfunction appears to be a manifestation of a systemic process: A report from the Women's Ischemia Syndrome Evaluation - Coronary Vascular Dysfunction (WISE-CVD) study.

PLoS ONE, 2021
BackgroundCoronary microvascular dysfunction (CMD) is prevalent in symptomatic women with ischemia but no obstructive coronary artery disease (INOCA). Urine albumin-creatinine ratio (UACR) is a measure of renal microvascular endothelial dysfunction. Both
Sawan Jalnapurkar, Sofy Landes, Janet Wei, Puja K Mehta, Chrisandra Shufelt, Margo Minissian, Carl J Pepine, Eileen Handberg, Galen Cook-Wiens, George Sopko, C Noel Bairey Merz   +10 more
doaj   +1 more source

Microvascular dysfunction: Determinants and treatment, with a focus on hyperglycemia

Endocrine and Metabolic Science, 2021
Individuals with prediabetes or type 2 diabetes have an increased risk of diseases that are partly or entirely of microvascular origin (e.g. (lacunar) stroke, depression, cognitive decline, retinopathy, heart failure, chronic kidney disease, and neuropathy). These diseases are expressions of advanced microvascular dysfunction (MVD).
Alfons J.H.M. Houben, Coen D.A. Stehouwer   +1 more
openaire   +2 more sources

Treatment of coronary microvascular dysfunction [PDF]

Cardiovascular Research, 2020
Abstract Contemporary data indicate that patients with signs and symptoms of ischaemia and non-obstructive coronary artery disease (INOCA) often have coronary microvascular dysfunction (CMD) with elevated risk for adverse outcomes. Coronary endothelial (constriction with acetylcholine) and/or microvascular (limited coronary flow reserve ...
Colin Berry, Hiroki Shimokawa, Carl J Pepine, C Noel Bairey Merz   +3 more
openaire   +2 more sources

Progression of coronary microvascular dysfunction to heart failure with preserved ejection fraction: a case report

Journal of Medical Case Reports, 2019
Background In women with evidence of ischemia and no obstructive coronary artery disease the underlying mechanism is most often attributed to coronary microvascular dysfunction.
Sandy Joung, Janet Wei, Michael D. Nelson, Haider Aldiwani, Chrisandra Shufelt, Balaji Tamarappoo, Daniel Berman, Louise E. J. Thomson, C. Noel Bairey Merz   +8 more
doaj   +1 more source

Microvascular dysfunction following cardiopulmonary bypass plays a central role in postoperative organ dysfunction

Frontiers in Medicine, 2023
Despite significant advances in surgical technique and strategies for tissue/organ protection, cardiac surgery involving cardiopulmonary bypass is a profound stressor on the human body and is associated with numerous intraoperative and postoperative ...
Shawn Kant, Debolina Banerjee, Sharif A. Sabe, Frank Sellke, Jun Feng   +4 more
doaj   +1 more source

Diagnosis, Pathophysiology and Management of Microvascular Dysfunction in Diabetes Mellitus

Diagnostics
Microcirculation is an essential system that regulates oxygen and nutrients to cells and tissues in response to various environmental stimuli and pathophysiological conditions. Diabetes mellitus can cause microvascular complications including nephropathy,
Yih-Kuen Jan, Nicolas Kelhofer, Tony Tu, Owaise Mansuri, Kingsley Onyemere, Shruti Dave, Suguna Pappu   +6 more
doaj   +1 more source

Microvascular Dysfunction Following Cardioplegic Arrest and Cardiopulmonary Bypass: Impacts of Diabetes and Hypertension

Biomedicines
Cardioplegic arrest and cardiopulmonary bypass (CP/CPB) are known to engender microvascular dysfunction in patients undergoing cardiac surgery. These effects are significantly varied by patient comorbidities including diabetes and hypertension.
Meghamsh Kanuparthy, Rishik Manthana, Himanshu Kaushik, Kathy Xiang, Jad Hamze, David Marimekala, Jun Feng, Frank W. Sellke   +7 more
doaj   +1 more source

Non-pharmacological Treatment of Refractory Angina and Microvascular Angina

Biomedicines, 2020
Refractory angina (RA) is defined as debilitating anginal symptoms despite the optimal guideline-directed combination of medical, percutaneous, and surgical therapies.
Kudrat Rakhimov, Tommaso Gori
doaj   +1 more source

Radionuclide imaging methods in the diagnosis of microvascular dysfunction in non-obstructive coronary artery disease

Российский кардиологический журнал, 2022
Non-obstructive coronary artery disease is generally considered as a favorable type of pathology, however, a number of studies indicate that in non-obstructive atherosclerosis, the risk of such cardiovascular events as myocardial infarction, ischemic ...
A. N. Maltseva, A. V. Mochula, K. V. Kopyeva, E. V. Grakova, K. V. Zavadovsky   +4 more
doaj   +1 more source

Pharmacotherapy for coronary microvascular dysfunction [PDF]

European Heart Journal - Cardiovascular Pharmacotherapy, 2015
Coronary microvascular dysfunction (CMD) has been increasingly recognized as an important cardiac condition that can cause signs and symptoms of myocardial ischaemia in various clinical settings. The dysfunction is located on the level of the coronary microcirculation with a vessel diameter of
Peter, Ong, Anastasios, Athanasiadis, Udo, Sechtem   +2 more
openaire   +2 more sources