Results 31 to 40 of about 131,858 (288)

THE METABOLIC-MICROVASCULAR DYSREGULATION SYNDROME

Artery Research, 2017
Microvascular and metabolic physiology are inextricably linked. Thus, metabolic dysfunction impairs microvascular function and microvascular dysfunction impairs normal metabolism.
Coen D.A. Stehouwer
doaj   +1 more source

MiR-30 promotes fatty acid beta-oxidation and endothelial cell dysfunction and is a circulating biomarker of coronary microvascular dysfunction in pre-clinical models of diabetes

Cardiovascular Diabetology, 2022
Background Type 2 diabetes (T2D) is associated with coronary microvascular dysfunction, which is thought to contribute to compromised diastolic function, ultimately culminating in heart failure with preserved ejection fraction (HFpEF).
Shawn Veitch, Makon-Sébastien Njock, Mark Chandy, M. Ahsan Siraj, Lijun Chi, HaoQi Mak, Kai Yu, Kumaragurubaran Rathnakumar, Carmina Anjelica Perez-Romero, Zhiqi Chen, Faisal J. Alibhai, Dakota Gustafson, Sneha Raju, Ruilin Wu, Dorrin Zarrin Khat, Yaxu Wang, Amalia Caballero, Patrick Meagher, Edward Lau, Lejla Pepic, Henry S. Cheng, Natalie J. Galant, Kathryn L. Howe, Ren-Ke Li, Kim A. Connelly, Mansoor Husain, Paul Delgado-Olguin, Jason E. Fish   +27 more
doaj   +1 more source

Coronary Microvascular Dysfunction

Journal of the Society for Cardiovascular Angiography & Interventions
Coronary microvascular dysfunction (CMD) is a key mechanism underlying ischemic heart disease (IHD), yet its diagnosis and treatment remain challenging. This article presents a comprehensive overview of CMD research, covering its pathogenesis, diagnostic criteria, assessment techniques, risk factors, and therapeutic strategies.
Yader Sandoval, Joaquin E. Cigarroa, George D. Dangas, Alexandra J. Lansky, Srihari S. Naidu, Sunil V. Rao, Arnold H. Seto, Samit Shah, Adhir R. Shroff, Olga Toleva, Jennifer A. Tremmel, Robert F. Riley, Timothy D. Henry, Connie S. Baumgard, Ilka Bijoux, Lisa Cavaliere, Casey Culbertson, Regina Deible, Maya El-Sabban, Jeremy Jackson, Melissa Jackson, Bethany Kalich, Vanessa Long, Amy Newell, Daya Perkins, Krish Ramakrishnan, Karen Russell, Vinod Sharma, Nick E.J. West, Chrissy Whalen-Morton, Paul Underwood, Kristi Winterfeldt, Cezary Wojcik, Steve Zizzo   +33 more
  +6 more sources

Skin microvascular vasodilatory capacity in offspring of two parents with Type 2 diabetes [PDF]

, 2001
Aims<br/> Microvascular dysfunction occurs in Type 2 diabetes and in subjects with fasting hyperglycaemia. It is unclear whether this dysfunction relates to dysglycaemia.
Shore, A.C., Lowe, G.D., Lee, B.C., B. C. Lee, Clark, P.M., A. Rumley, J. E. Tooke, A. T. Hattersley, Rumley, A., Tooke, J.E., G. D. Lowe, A. C. Shore, J. M. Humphreys, Humphreys, J.M., P. M. Clark, Hattersley, A.T.   +15 more
core   +1 more source

Microvascular Dysfunction as a Possible Link Between Heart Failure and Cognitive Dysfunction.

, 2023
BACKGROUND Microvascular function in the brain and heart may play an important role in the course of patients with heart failure (HF), but its relationship with ventricular and cognitive function is not well understood.
Chen, Hao Yu, Hillier, Elizabeth, Hafyane, Tarik, Friedrich, Matthias G, Fischer, Kady, Covone, Jason   +5 more
core   +1 more source

Fluoroscopic methods of assessment of coronary microvascular dysfunction – a review of literature [PDF]

Българска кардиология
A large proportion of patients with angina and evidence of myocardial ischemia do not have obstructive coronary disease. One of the main mechanisms of ischemia/angina with non-obstructive coronary arteries is coronary microvascular dysfunction, which is ...
R. Grigorov, S. Yambolov
doaj   +3 more sources

Nailfold capillaroscopy: A sensitive method for evaluating microvascular involvement in children with SARS-CoV-2 infection.

, 2021
Objectives: The hyperinflammatory state and the viral invasion may result in endothelial dysfunction in SARS-CoV-2 infection. Although a method foreseeing microvascular dysfunction has not been defined yet, studies conducted in patients diagnosed with ...
Uysalol, Metin, Kayaalp, Gülşah Kavrul, Somer, Ayper, Ömeroglu, Rukiye Eker, Demirbuga, Asuman, Gümüş, Süheyla, Yıldız, Raif, Çakmak, Figen, Ayaz, Nuray, Demirkol, Demet, Torun, Selda   +10 more
core   +1 more source

Capillary function progressively deteriorates in prodromal Alzheimer’s disease: A longitudinal MRI perfusion study

Aging Brain, 2022
Cardiovascular risk factors are associated with the development of Alzheimer’s disease (AD), and increasing evidence suggests that cerebral microvascular dysfunction plays a vital role in the disease progression.
Lasse S. Madsen, Rune B. Nielsen, Peter Parbo, Rola Ismail, Irene K. Mikkelsen, Hanne Gottrup, Leif Østergaard, David J. Brooks, Simon F. Eskildsen   +8 more
doaj   +1 more source

International prospective cohort study of microvascular angina – Rationale and design

International Journal of Cardiology: Heart & Vasculature, 2020
Background: Patients with signs and symptoms of myocardial ischemia and non-obstructive coronary artery disease (CAD) frequently have coronary functional abnormalities, including coronary microvascular dysfunction. Those with the latter are grouped under
Akira Suda, Jun Takahashi, John F. Beltrame, Colin Berry, Paolo G. Camici, Filippo Crea, Javier Escaned, Tom Ford, Juan Carlos Kaski, Takahiko Kiyooka, Puja K. Metha, Peter Ong, Yukio Ozaki, Carl Pepine, Ornella Rimoldi, Basmah Safdar, Udo Sechtem, Kenichi Tsujita, Eric Yii, C. Noel Bairey Merz, Hiroaki Shimokawa   +20 more
doaj   +1 more source

Microvascular dysfunction: Determinants and treatment, with a focus on hyperglycemia

Endocrine and Metabolic Science, 2021
Individuals with prediabetes or type 2 diabetes have an increased risk of diseases that are partly or entirely of microvascular origin (e.g. (lacunar) stroke, depression, cognitive decline, retinopathy, heart failure, chronic kidney disease, and neuropathy). These diseases are expressions of advanced microvascular dysfunction (MVD).
Alfons J.H.M. Houben, Coen D.A. Stehouwer   +1 more
openaire   +2 more sources