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Microvascular and Endothelial Dysfunction in Prediabetes
Prediabetes is a significant metabolic status since there is high potential for future progression of diabetes mellitus (DM). People with prediabetes are at increased risk of cardiovascular disease (CVD) and mortality.
Stamatina Lamprou +7 more
doaj +3 more sources
Coronary microvascular dysfunction [PDF]
Patients with coronary microvascular dysfunction (CMVD) represent a widespread population and despite the good prognosis, many of them have a poor quality of life with strong limitations in their daily activities because of the angina symptoms.
Sucato V. +4 more
+8 more sources
Coronary Microvascular Dysfunction [PDF]
Over the past couple of decades, accumulating evidence has shown that structural and functional abnormalities of coronary microvasculature are highly prevalent, associated with adverse clinical outcomes in patients with various cardiovascular diseases. The term coronary microvascular dysfunction (CMD) has been coined to refer to this clinical condition
Shigeo Godo +4 more
openaire +3 more sources
Inflammation in Coronary Microvascular Dysfunction [PDF]
Chronic low-grade inflammation is involved in coronary atherosclerosis, presenting multiple clinical manifestations ranging from asymptomatic to stable angina, acute coronary syndrome, heart failure and sudden cardiac death. Coronary microvasculature consists of vessels with a diameter less than 500 μm, whose potential structural and functional ...
Marios Sagris +7 more
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Microvascular Dysfunction in Hypertrophic Cardiomyopathy
Myocardial ischemia is an established pathophysiological feature of hypertrophic cardiomyopathy (HCM) that impacts various clinical features, including heart failure (HF) and sudden cardiac death (SCD). The major determinant of myocardial ischemia in HCM is coronary microvascular dysfunction (CMD) in the absence of epicardial coronary artery ...
Francesco Pelliccia +3 more
openaire +2 more sources
Coronary microvascular dysfunction: an update [PDF]
Many patients undergoing coronary angiography because of chest pain syndromes, believed to be indicative of obstructive atherosclerosis of the epicardial coronary arteries, are found to have normal angiograms. In the past two decades, a number of studies have reported that abnormalities in the function and structure of the coronary microcirculation may
Crea, Filippo +2 more
openaire +4 more sources
Coronary Microvascular Dysfunction, Microvascular Angina, and Management [PDF]
Recent analyses have found that coronary microvascular dysfunction (CMD) portends a poor prognosis in patients with and without obstructive epicardial coronary artery disease (CAD). Chest pain in the absence of epicardial CAD is a common entity. Angina caused by CMD, microvascular angina (MVA), is often indistinguishable from that caused by obstructive
Adrián I, Löffler, Jamieson M, Bourque
openaire +2 more sources
Role of coronary microvascular dysfunction in heart failure with preserved ejection fraction [PDF]
Heart failure with preserved ejection fraction (HFpEF) is one of the greatest unmet needs in modern medicine. The lack of an appropriate therapy may reflect the lack of an accurate comprehension of its pathophysiology.
Francesco Tona +3 more
doaj +1 more source
THE METABOLIC-MICROVASCULAR DYSREGULATION SYNDROME
Microvascular and metabolic physiology are inextricably linked. Thus, metabolic dysfunction impairs microvascular function and microvascular dysfunction impairs normal metabolism.
Coen D.A. Stehouwer
doaj +1 more source
Heart failure with preserved ejection fraction (HFpEF) has been recognized as the greatest single unmet need in cardiovascular medicine. Indeed, the morbi-mortality of HFpEF is high and as the population ages and the comorbidities increase, so ...
Lauriane Cornuault +4 more
doaj +1 more source

