Results 41 to 50 of about 131,858 (288)

Coronary microvascular dysfunction as a chronic inflammatory state: Is there a role for omega-3 fatty acid treatment?

American Heart Journal Plus, 2022
Coronary microvascular dysfunction is a ubiquitous pathologic process that is operational in ischemia with no obstructive coronary artery disease and other cardiovascular disorders including heart failure with preserved ejection fraction. It may, in fact,
Ellen C. Keeley, Eileen M. Handberg, Janet Wei, C. Noel Bairey Merz, Carl J. Pepine   +4 more
doaj   +1 more source

Neutrophil extracellular traps drive intestinal microvascular endothelial ferroptosis by impairing Fundc1-dependent mitophagy

Redox Biology, 2023
Microvascular endothelial damage caused by intestinal ischemia‒reperfusion (II/R) is a primary catalyst for microcirculation dysfunction and enterogenous infection.
Chengnan Chu, Xinyu Wang, Chao Yang, Fang Chen, Lin Shi, Weiqi Xu, Kai Wang, Baochen Liu, Chenyang Wang, Dongping Sun, Weiwei Ding   +10 more
doaj   +1 more source

Pathophysiology of Coronary Microvascular Dysfunction

Circulation Journal, 2022
Ischemic heart disease (IHD) is commonly recognized as the consequence of coronary atherosclerosis and obstructive coronary artery disease (CAD). However, a significant number of patients may present angina or myocardial infarction even in the absence of any significant coronary artery stenosis and impairment of the coronary microcirculation has been ...
Crea, Filippo, Montone, Rocco A., Rinaldi, Riccardo   +2 more
openaire   +3 more sources

Degree of adiposity and obesity severity is associated with cutaneous microvascular dysfunction in type 2 diabetes

, 2021
Backgrounds and aims: Obesity and diabetes independently contribute to cutaneous microvascular dysfunction via pathological processes that are not fully understood.
Baker, Michael K., Johnson, Nathan A., Sabag, Angelo (R19940), Way, Kimberley L., Gerofi, James, Caterson, Ian D., Sultana, Rachelle N., Twigg, Stephen M., Chuter, Vivienne H., Lanting, Sean M. (R20950)   +9 more
core   +1 more source

Coronary endothelial dysfunction appears to be a manifestation of a systemic process: A report from the Women's Ischemia Syndrome Evaluation - Coronary Vascular Dysfunction (WISE-CVD) study.

PLoS ONE, 2021
BackgroundCoronary microvascular dysfunction (CMD) is prevalent in symptomatic women with ischemia but no obstructive coronary artery disease (INOCA). Urine albumin-creatinine ratio (UACR) is a measure of renal microvascular endothelial dysfunction. Both
Sawan Jalnapurkar, Sofy Landes, Janet Wei, Puja K Mehta, Chrisandra Shufelt, Margo Minissian, Carl J Pepine, Eileen Handberg, Galen Cook-Wiens, George Sopko, C Noel Bairey Merz   +10 more
doaj   +1 more source

Treatment of coronary microvascular dysfunction [PDF]

Cardiovascular Research, 2020
Abstract Contemporary data indicate that patients with signs and symptoms of ischaemia and non-obstructive coronary artery disease (INOCA) often have coronary microvascular dysfunction (CMD) with elevated risk for adverse outcomes. Coronary endothelial (constriction with acetylcholine) and/or microvascular (limited coronary flow reserve ...
Colin Berry, Hiroki Shimokawa, Carl J Pepine, C Noel Bairey Merz   +3 more
openaire   +2 more sources

Progression of coronary microvascular dysfunction to heart failure with preserved ejection fraction: a case report

Journal of Medical Case Reports, 2019
Background In women with evidence of ischemia and no obstructive coronary artery disease the underlying mechanism is most often attributed to coronary microvascular dysfunction.
Sandy Joung, Janet Wei, Michael D. Nelson, Haider Aldiwani, Chrisandra Shufelt, Balaji Tamarappoo, Daniel Berman, Louise E. J. Thomson, C. Noel Bairey Merz   +8 more
doaj   +1 more source

Microvascular dysfunction following cardiopulmonary bypass plays a central role in postoperative organ dysfunction

Frontiers in Medicine, 2023
Despite significant advances in surgical technique and strategies for tissue/organ protection, cardiac surgery involving cardiopulmonary bypass is a profound stressor on the human body and is associated with numerous intraoperative and postoperative ...
Shawn Kant, Debolina Banerjee, Sharif A. Sabe, Frank Sellke, Jun Feng   +4 more
doaj   +1 more source

Application of a novel method for subsequent evaluation of sinusoids and postsinusoidal venules after ischemia-reperfusion injury of rat liver [PDF]

, 1998
Although several intravital fluorescence microscopic studies demonstrated that microcirculatory derangement is induced during liver ischemia-reperfusion, these data were obtained from randomly selected microvascular areas and microvessels, Repeated ...
Todoroki, T., Schildberg, Friedrich Wilhelm, Kondo, Tadashi, Okamoto, S., Messmer, K., Hirano, T.   +5 more
core   +1 more source

Microvascular Dysfunction and Cognitive Impairment [PDF]

Cellular and Molecular Neurobiology, 2016
The impact of vascular risk factors on cognitive function has garnered much interest in recent years. The appropriate distribution of oxygen, glucose, and other nutrients by the cerebral vasculature is critical for proper cognitive performance. The cerebral microvasculature is a key site of vascular resistance and a preferential target for small vessel
T Michael, De Silva, Frank M, Faraci
openaire   +2 more sources