Results 161 to 170 of about 15,195 (308)

A novel role for peptidylarginine deiminases in microvesicle release reveals therapeutic potential of PAD inhibition in sensitizing prostate cancer cells to chemotherapy

open access: yesJournal of Extracellular Vesicles, 2015
Introduction Protein deimination, defined as the post-translational conversion of protein-bound arginine to citrulline, is carried out by a family of 5 calcium-dependent enzymes, the peptidylarginine deiminases (PADs) and has been linked to various ...
Sharad Kholia   +6 more
semanticscholar   +1 more source

Exosome‐Based Theranostic for Gastrointestinal Cancer: Advances in Biomarker Discovery and Therapeutic Engineering

open access: yesSmall Methods, EarlyView.
This review explores the dual roles of exosomes in gastrointestinal (GI) cancers as diagnostic biomarkers and therapeutic agents. It highlights advancements in exosomal miRNAs, lncRNAs, circRNAs, and proteins for cancer detection and prognosis. The study also examines engineering strategies for exosome‐based drug delivery systems, their potential to ...
Mohit J. Mehta   +7 more
wiley   +1 more source

Follicular Dendritic Cells Carry MHC Class II-Expressing Microvesicles at Their Surface [PDF]

open access: bronze, 2000
Kristin Denzer   +5 more
openalex   +1 more source

Glycopattern comparison of sperm and exosomes from conventional in vitro fertilization and rescue intracytoplasmic sperm injection: Enhancing sperm motility through exosome‐mediated glycan modulation

open access: yesVIEW, EarlyView.
Infertility is a global concern, with male factors contributing to nearly half of cases. This study compared glycopatterns of sperm and sperm‐derived exosomes from conventional IVF and rescue ICSI (RICSI) patients, revealing key differences in glycan expression.
Muhammad Anas Ramzan   +10 more
wiley   +1 more source

Rab4 Regulates Formation of Synaptic-like Microvesicles from Early Endosomes in PC12 Cells [PDF]

open access: green, 2001
Heidi de Wit   +5 more
openalex   +1 more source

Microvesicles in platelet concentrates for transfusion [PDF]

open access: yes, 2000
The key objective of this study was to examine whether leucocyte depletion generated or removed platelet-derived microvesicles in platelet concentrates for transfusion. Three in-process leucocyte removal filters for pooled buffy coat derived platelet concentrates, i. e.
openaire   +2 more sources

Detection of KRAS Mutations Using Extracellular Vesicle DNA in Colorectal Cancer Patients

open access: yesCancer Science, EarlyView.
DNA in the circulating extracellular vesicle (evDNA) has superior potential for detecting KRAS mutations compared with circulating tumor DNA, possibly because evDNA comprises very long, undamaged DNA strands. The analysis using evDNA demonstrated that heterogeneity related to KRAS exists at a higher frequency than we had anticipated.
Sho Kuriyama   +15 more
wiley   +1 more source

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