Results 171 to 180 of about 18,155 (253)

Immunomodulatory Mechanisms of Chronic Wound Healing: Translational and Clinical Relevance

open access: yesMedComm, Volume 6, Issue 11, November 2025.
This graphical abstract illustrates the immunomodulation of chronic wounds through various therapeutic approaches aimed at regulating the immune response to promote healing. ABSTRACT Chronic wounds—such as diabetic foot ulcers (DFUs), pressure ulcers (PUs), and venous leg ulcers (VLUs)—pose a serious clinical challenge due to their prolonged ...
Mahrukh Riaz   +3 more
wiley   +1 more source

Molecular Encoding of Ischemic Stroke and its Resolution after Human Neural Stem Cell Therapy by Extracellular Vesicles

open access: yesMedComm, Volume 6, Issue 11, November 2025.
EVs can cross the blood–brain barrier and enter systemic circulation. By analyzing EV RNA cargoes before and after stroke, and following hNSC transplantation, our study shows that EV RNAs accurately reflect stroke pathology and provide insights into how hNSCs promote stroke recovery. These findings suggest that EV RNA profiles could serve as diagnostic
Chuheng Chang   +4 more
wiley   +1 more source

Bioengineered Extracellular Vesicles in Emerging Cancer Vaccine Platforms

open access: yesSmall Science, Volume 5, Issue 11, November 2025.
This review highlights recent advances in engineering extracellular vesicles (EVs) as next‐generation cancer vaccines. It outlines their biological roles and antigen‐presenting capacity, explores key strategies for antigen loading and delivery optimization, and summarizes preclinical and clinical applications using EVs from diverse immune and tumor ...
Wonkyung Ahn   +4 more
wiley   +1 more source

Microvesicle release from inner segments of healthy photoreceptors is a conserved phenomenon in mammalian species

open access: yesDisease Models & Mechanisms, 2022
Tylor R. Lewis   +9 more
doaj   +1 more source

Inter‐Organ Crosstalk and Regulatory Mechanisms of Skeletal Muscle‐Derived Extracellular Vesicles in Systemic Metabolic Homeostasis

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Extracellular vesicles (EVs), including exosomes, play a pivotal role in intercellular communication by facilitating the transfer of bioactive molecules between cells. These vesicles, which encompass a variety of subtypes such as exosomes, microvesicles and apoptotic bodies, carry functional proteins, mRNAs, miRNAs and other molecular cargo ...
Zhuoying Wu   +3 more
wiley   +1 more source

Extracellular vesicles mediate intercellular communication: Transfer of functionally active microRNAs by microvesicles into phagocytes [PDF]

open access: bronze, 2017
Laura Claßen   +10 more
openalex   +1 more source

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