Mesenchymal Stem Cell‐Derived Exosomes: A Promising Therapeutic Strategy for Age‐Related Diseases
Cell Proliferation, EarlyView.Mechanisms of MSC‐Exos in the treatment of age‐related diseases. A Immunomodulatory and anti‐inflammatory, MSC‐Exos mediate immunomodulatory and anti‐inflammatory effects by regulating the polarisation of T cells and macrophages, promoting an anti‐inflammatory state while inhibiting pro‐inflammatory responses; B Suppression of oxidative stress, MSC ...
Bohua Wei +5 more
wiley +1 more source
Human Colorectal Cancer Cells Induce T-Cell Death Through Release of Proapoptotic Microvesicles: Role in Immune Escape [PDF]
, 2005 Veronica Huber +16 more
openalex +1 more source
A review of the equine suspensory ligament: Injury prone yet understudied
Equine Veterinary Journal, EarlyView.Abstract The suspensory ligament (SL) is a key component of the elaborate and highly adapted suspensory apparatus in the horse. In addition to contributing to stabilisation of the metacarpophalangeal joint, the SL has a spring like function to reduce the energetic cost of locomotion.
Deborah J. Guest +2 more
wiley +1 more source
Human Tumor-Released Microvesicles Promote the Differentiation of Myeloid Cells with Transforming Growth Factor-β–Mediated Suppressive Activity on T Lymphocytes [PDF]
, 2006 Roberta Valenti +9 more
openalex +1 more source
Snakebites and microvesicles: Popping bubbles [PDF]
Research and Practice in Thrombosis and Haemostasis, 2019 Bos, M.H.A., Versteeg, H.H.
openaire +4 more sources
The FEBS Journal, EarlyView.The mammary microenvironment has been shown to suppress tumor progression by redirecting cancer cells to adopt a normal mammary epithelial progenitor fate in vivo. Here, we test the hypothesis that mitochondrial transfer from mammary epithelial cells to breast cancer cells plays a role in this redirection process.
Julie Sofie Bjerring +4 more
wiley +1 more source
Cholesterol Enrichment of Human Monocyte/Macrophages Induces Surface Exposure of Phosphatidylserine and the Release of Biologically-Active Tissue Factor–Positive Microvesicles [PDF]
, 2006 Ming‐Lin Liu +4 more
openalex +1 more source
WNT5a export onto extracellular vesicles studied at single‐molecule and single‐vesicle resolution
The FEBS Journal, EarlyView.WNT signaling, which orchestrates tissue development and homeostasis, is mediated by hydrophobic WNT proteins traveling from secreting to receiving cells on various carriers. Here, fusion constructs of fluorescent proteins with WNT5a were developed and functionally validated.
Antonia Schubert +16 more
wiley +1 more source
Extracellular vesicles in multiple myeloma: pathogenesis and therapeutic application
The FEBS Journal, EarlyView.Multiple myeloma is characterised by the clonal proliferation of plasma cells in the bone marrow. Extracellular vesicles (EVs) are a key component of cell‐to‐cell communication within the bone marrow microenvironment, promoting tumour growth, bone remodelling, immune modulation, angiogenesis and therapeutic resistance.
Chloe Wylie +3 more
wiley +1 more source
Alteration of Marrow Cell Gene Expression, Protein Production, and Engraftment into Lung by Lung-Derived Microvesicles: A Novel Mechanism for Phenotype Modulation [PDF]
, 2007 Jason M. Aliotta +16 more
openalex +1 more source