Results 191 to 200 of about 15,195 (308)

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

open access: yesMass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy

open access: yesMedComm, Volume 6, Issue 5, May 2025.
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes   +4 more
wiley   +1 more source

Membrane Microvesicles as Actors in the Establishment of a Favorable Prostatic Tumoral Niche: A Role for Activated Fibroblasts and CX3CL1-CX3CR1 Axis [PDF]

open access: bronze, 2009
Donatello Castellana   +6 more
openalex   +1 more source

α‐Synuclein in Parkinson's Disease: From Bench to Bedside

open access: yesMedicinal Research Reviews, Volume 45, Issue 3, Page 909-946, May 2025.
ABSTRACT α‐Synuclein (α‐syn), a pathological hallmark of PD, is emerging as a bridging element at the crossroads between neuro/immune‐inflammatory responses and neurodegeneration in PD. Several evidence show that pathological α‐syn accumulates in neuronal and non‐neuronal cells (i.e., neurons, microglia, macrophages, skin cells, and intestinal cells ...
Gabriele Bellini   +8 more
wiley   +1 more source

Induction of Lymphocyte Apoptosis by Tumor Cell Secretion of FasL-bearing Microvesicles

open access: bronze, 2002
Giovanna Andreola   +15 more
openalex   +1 more source

Improving Bovine Embryo Development and Quality Using Bovine Oviductal Epithelial Cell‐Derived Conditioned Medium (bOEC‐CM)

open access: yesVeterinary Medicine and Science, Volume 11, Issue 3, May 2025.
The study investigated the effects of bOEC‐CM on bovine in vitro embryo development. CM from Day 3 enhances blastocyst rate and positively affects the ICM and TE in blastocysts and increases the expression of development‐specific genes. bOEC‐CM may serve as a superior supplement during the final five embryo culture days.
Saeed Kazemi Hosseinabadi   +6 more
wiley   +1 more source

Engineered nanoparticles potentials in male reproduction

open access: yesAndrology, Volume 13, Issue 4, Page 694-705, May 2025.
Abstract Background The escalating prevalence of fertility problems in the aging population necessitates a comprehensive exploration of contributing factors, extending beyond environmental concerns, work‐related stress, and unhealthy lifestyles. Among these, the rising incidence of testicular disorders emerges as a pivotal determinant of fertility ...
Feifei Zhao   +8 more
wiley   +1 more source

MetALD: New Perspectives on an Old Overlooked Disease

open access: yesLiver International, Volume 45, Issue 5, May 2025.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) and alcohol‐associated liver disease (ALD) are the major contributors to the liver disease burden globally. The rise in these conditions is linked to obesity, type 2 diabetes, metabolic syndrome and increased alcohol consumption.
Gustavo Ayares   +8 more
wiley   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, Volume 599, Issue 7, Page 1055-1074, April 2025.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

Microvesicles: mediators of extracellular communication during cancer progression [PDF]

open access: green, 2010
Vandhana Muralidharan-Chari   +3 more
openalex   +1 more source

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