Results 221 to 230 of about 15,195 (308)

Small Extracellular Vesicle‐Derived Nicotinamide Phosphoribosyltransferase (NAMPT) Induces Acyl‐Coenzyme A Synthetase SLC27A4‐Mediated Glycolysis to Promote Hepatocellular Carcinoma

Journal of Extracellular Vesicles, Volume 14, Issue 4, April 2025.
NAMPT delivered by metastatic HCC cells‐derived sEV upregulates SLC27A4 expression via TLR4/NF‐кB dependent pathway. SLC27A4 acts as an acyl‐CoA synthetase and increases the level of intracellular TG, leading to DHAP‐mediated transition between lipogenesis and glycolysis.
Cherlie Lot Sum Yeung, Tung Him Ng, Charlotte Jiaqi Lai, Tingmao Xue, Xiaowen Mao, Sze Keong Tey, Regina Cheuk Lam Lo, Chun‐Fung Sin, Kwan Ming Ng, Danny Ka Ho Wong, Lung‐Yi Mak, Man‐Fung Yuen, Irene Oi‐Lin Ng, Peihua Cao, Yi Gao, Jing Ping Yun, Judy Wai Ping Yam   +16 more
wiley   +1 more source

Circulating extracellular vesicles as potential biomarkers and mediators of acute respiratory distress syndrome in sepsis. [PDF]

Sci Rep
do Nascimento MF, Ferreira LRP, Vieira Junior JM, Deheinzelin D, Aparecida Santos Nussbaum AC, Toshihiro Sakamoto LH, Vasconcelos RO, Salomao R, Waisberg J, Azevedo LCP, Chammas R, Real JM.   +11 more
europepmc   +1 more source

The influence of membrane physical properties on microvesicle release in human erythrocytes

, 2009
Laurie J. Gonzalez, Elizabeth Gibbons, Elizabeth G. Bailey, Jeremy L. Fairbourn, Thaothanh Nguyen, Samantha K. Smith, Katrina B. Best, Jennifer Nelson, Allan M. Judd, John D. Bell   +9 more
openalex   +2 more sources

Yersinia pestis Actively Inhibits the Production of Extracellular Vesicles by Human Neutrophils

Journal of Extracellular Vesicles, Volume 14, Issue 4, April 2025.
Typically, neutrophils respond to invading pathogens by altering the cargo packaged into EVs and increasing EV release, which enhances antimicrobial responses. However, we show here that the bacterial pathogen Yersinia pestis injects Yop effector proteins into neutrophils to actively inhibit EV biogenesis, resulting in limited EV release and ...
Katelyn R. Sheneman, Timothy D. Cummins, Michael L. Merchant, Joshua L. Hood, Silvia M. Uriarte, Matthew B. Lawrenz   +5 more
wiley   +1 more source

Plasma‐Derived Exosomal i‐tRF‐LeuCAA as Biomarker for Glioma Diagnosis and Promoter of Epithelial‐Mesenchymal Transition via TPM4 Regulation

CNS Neuroscience &Therapeutics, Volume 31, Issue 4, April 2025.
i‐tRF‐LeuCAA could be served as a non‐invasive biomarker in the diagnosis and prognosis of glioma. i‐tRF‐LeuCAA may indirectly regulate TPM4 expression and influence epithelial–mesenchymal transition, which may promote glioma progression. ABSTRACT Aims This study aimed to discover plasma‐derived exosomal tsRNAs that serve as novel diagnostic biomarkers
Hongyu Liu, Wentao Hu, Lijun Zhang, Ze Li, Jialin Liu, Ling Chen   +5 more
wiley   +1 more source

A Low-Modulus Phosphatidylserine-Exposing Microvesicle Alleviates Skin Inflammation via Persistent Blockade of M1 Macrophage Polarization. [PDF]

Int J Mol Sci
Zhang Z, Mo Y, Xu S, Jiang L, Peng Y, ZhuGe Y, Su Z, Xiang Q, Zeng R, Zhang G.   +9 more
europepmc   +1 more source

Microvesicles from Mesenchymal Stromal Cells Protect against Acute Kidney Injury

, 2009
Joseph V. Bonventre
openalex   +1 more source

Cell therapy based on stem cells or their extracellular vesicles during kidney graft preservation: Current state of the art and novelties

Clinical and Translational Discovery, Volume 5, Issue 2, April 2025.
Nessma Chenaf‐Benabdelmoumene, Thierry Hauet, Clara Steichen   +2 more
wiley   +1 more source

Relevance of anti-platelet factor 4/heparin antibodies and platelet activation in systemic inflammatory diseases and thrombosis disorders: insight from the COVID-19 pandemic. [PDF]

Res Pract Thromb Haemost
Gendron N, Helley D, Thaler J, Faille D, Le Beller C, Gruest M, Hadjadj J, Philippe A, Zeco F, Courbebaisse M, Darnige L, Amara W, Calmette L, Parfait B, Auditeau C, Chocron R, Khider L, Mauge L, Espitia O, Friedlander G, Ajzenberg N, Lebeaux D, Planquette B, Sanchez O, Diehl JL, COVID-HOP Study Group, Lillo-Le Louet A, Terrier B, Smadja DM.   +28 more
europepmc   +1 more source

Tumor-Derived Microvesicles Promote Regulatory T Cell Expansion and Induce Apoptosis in Tumor-Reactive Activated CD8+ T Lymphocytes

, 2009
Eva Wieckowski, Carmen Visús, Marta Szajnik, Mirosław J. Szczepański, Walter J. Storkus, Theresa L. Whiteside   +5 more
openalex   +1 more source